{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2021:ITTIQ2WWNQVIFQVAXQ2FE2ARDH","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"280747dcb75dcec295e747bd75fa2d52801f4e78d253e03b8c6f9e1607946ae1","cross_cats_sorted":[],"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"stat.AP","submitted_at":"2021-07-29T06:17:35Z","title_canon_sha256":"2332ccdb861f066288f22a2b3936673372e568f2d2fc638bd58321dc841ad46c"},"schema_version":"1.0","source":{"id":"2107.13763","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2107.13763","created_at":"2026-07-05T03:01:39Z"},{"alias_kind":"arxiv_version","alias_value":"2107.13763v1","created_at":"2026-07-05T03:01:39Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2107.13763","created_at":"2026-07-05T03:01:39Z"},{"alias_kind":"pith_short_12","alias_value":"ITTIQ2WWNQVI","created_at":"2026-07-05T03:01:39Z"},{"alias_kind":"pith_short_16","alias_value":"ITTIQ2WWNQVIFQVA","created_at":"2026-07-05T03:01:39Z"},{"alias_kind":"pith_short_8","alias_value":"ITTIQ2WW","created_at":"2026-07-05T03:01:39Z"}],"graph_snapshots":[{"event_id":"sha256:d25829f2ec274ce6695846bd5200a498383a2711d0269a71da549f95342ad295","target":"graph","created_at":"2026-07-05T03:01:39Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2107.13763/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"Microbiome data analyses require statistical tools that can simultaneously decode microbes' reactions to the environment and interactions among microbes. We introduce CARlasso, the first user-friendly open-source and publicly available R package to fit a chain graph model for the inference of sparse microbial networks that represent both interactions among nodes and effects of a set of predictors. Unlike in standard regression approaches, the edges represent the correct conditional structure among responses and predictors that allows the incorporation of prior knowledge from controlled experim","authors_text":"Claudia Solis-Lemus, Yunyi Shen","cross_cats":[],"headline":"","license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"stat.AP","submitted_at":"2021-07-29T06:17:35Z","title":"CARlasso: An R package for the estimation of sparse microbial networks with predictors"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2107.13763","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:635cb114051e6f9c6c3344c53bf0d56e2f81d6b256605b45f6771258d6157cc2","target":"record","created_at":"2026-07-05T03:01:39Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"280747dcb75dcec295e747bd75fa2d52801f4e78d253e03b8c6f9e1607946ae1","cross_cats_sorted":[],"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"stat.AP","submitted_at":"2021-07-29T06:17:35Z","title_canon_sha256":"2332ccdb861f066288f22a2b3936673372e568f2d2fc638bd58321dc841ad46c"},"schema_version":"1.0","source":{"id":"2107.13763","kind":"arxiv","version":1}},"canonical_sha256":"44e6886ad66c2a82c2a0bc3452681119cd2a4c52d9ba22d2da46a452ebcdae13","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"44e6886ad66c2a82c2a0bc3452681119cd2a4c52d9ba22d2da46a452ebcdae13","first_computed_at":"2026-07-05T03:01:39.997681Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-05T03:01:39.997681Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"KYYERiGMTr74dofPXH9uRSZi8Izf0dGBUSZ6r3AYECPUjEI8iGXSuWGaeATsukQwPT9TC6n4PQv3NxiCcK7gDA==","signature_status":"signed_v1","signed_at":"2026-07-05T03:01:39.998025Z","signed_message":"canonical_sha256_bytes"},"source_id":"2107.13763","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:635cb114051e6f9c6c3344c53bf0d56e2f81d6b256605b45f6771258d6157cc2","sha256:d25829f2ec274ce6695846bd5200a498383a2711d0269a71da549f95342ad295"],"state_sha256":"2031231cb9476ee0af35333ff5468109eb15166724b9469f4248c6b5b77ebfe2"}