{"record_type":"pith_number_record","schema_url":"https://pith.science/schemas/pith-number/v1.json","pith_number":"pith:2022:JA4JYCKEJOKEE2CHF4D7DWUIZ3","short_pith_number":"pith:JA4JYCKE","schema_version":"1.0","canonical_sha256":"48389c09444b944268472f07f1da88ceffcc5d14155f6c9e16fa473bab29c00f","source":{"kind":"arxiv","id":"2208.07500","version":1},"attestation_state":"computed","paper":{"title":"The dynamics of viruslike capsid assembly and disassembly","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"physics.bio-ph","authors_text":"Alireza Ramezani, Jan C. M. van Hest, Mark Nguyen, Paul van der Schoot, Roya Zandi, Suzanne B. P. E. Timmermans, Toni Montalvo","submitted_at":"2022-08-16T02:17:52Z","abstract_excerpt":"Cowpea chlorotic mottle virus (CCMV) is a widely used model for virus replication studies. A major challenge lies in distinguishing between the roles of the interaction between coat proteins and that between the coat proteins and the viral RNA in assembly and disassembly processes. Here, we report on the spontaneous and reversible size conversion of the empty capsids of a CCMV capsid protein functionalized with a hydrophobic elastin-like polypeptide which occurs following a pH jump. We monitor the concentration of T = 3 and T = 1 capsids as a function of time and show that the time evolution o"},"verification_status":{"content_addressed":true,"pith_receipt":true,"author_attested":false,"weak_author_claims":0,"strong_author_claims":0,"externally_anchored":false,"storage_verified":false,"citation_signatures":0,"replication_records":0,"graph_snapshot":true,"references_resolved":false,"formal_links_present":false},"canonical_record":{"source":{"id":"2208.07500","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2022-08-16T02:17:52Z","cross_cats_sorted":[],"title_canon_sha256":"2a6dac8f6d46f42b7054c8fcb2877fb0e408b0df95a4236ddc8a56d4e37bec24","abstract_canon_sha256":"1b3eec3a5dd6ac1d76b0c73db0e4f94b055e4c22ec872b652a1ce49599d96448"},"schema_version":"1.0"},"receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-07-05T04:49:05.474393Z","signature_b64":"Ir1qYwJjxA19I0IEMkvwW5lhGXnduhK1mWGgG63H96STAGUXFsooAbzmB47UvgosX78/gRl4qhzf2n1lSLkaBA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"48389c09444b944268472f07f1da88ceffcc5d14155f6c9e16fa473bab29c00f","last_reissued_at":"2026-07-05T04:49:05.474027Z","signature_status":"signed_v1","first_computed_at":"2026-07-05T04:49:05.474027Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"graph_snapshot":{"paper":{"title":"The dynamics of viruslike capsid assembly and disassembly","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"physics.bio-ph","authors_text":"Alireza Ramezani, Jan C. M. van Hest, Mark Nguyen, Paul van der Schoot, Roya Zandi, Suzanne B. P. E. Timmermans, Toni Montalvo","submitted_at":"2022-08-16T02:17:52Z","abstract_excerpt":"Cowpea chlorotic mottle virus (CCMV) is a widely used model for virus replication studies. A major challenge lies in distinguishing between the roles of the interaction between coat proteins and that between the coat proteins and the viral RNA in assembly and disassembly processes. Here, we report on the spontaneous and reversible size conversion of the empty capsids of a CCMV capsid protein functionalized with a hydrophobic elastin-like polypeptide which occurs following a pH jump. We monitor the concentration of T = 3 and T = 1 capsids as a function of time and show that the time evolution o"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2208.07500","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2208.07500/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"aliases":[{"alias_kind":"arxiv","alias_value":"2208.07500","created_at":"2026-07-05T04:49:05.474089+00:00"},{"alias_kind":"arxiv_version","alias_value":"2208.07500v1","created_at":"2026-07-05T04:49:05.474089+00:00"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2208.07500","created_at":"2026-07-05T04:49:05.474089+00:00"},{"alias_kind":"pith_short_12","alias_value":"JA4JYCKEJOKE","created_at":"2026-07-05T04:49:05.474089+00:00"},{"alias_kind":"pith_short_16","alias_value":"JA4JYCKEJOKEE2CH","created_at":"2026-07-05T04:49:05.474089+00:00"},{"alias_kind":"pith_short_8","alias_value":"JA4JYCKE","created_at":"2026-07-05T04:49:05.474089+00:00"}],"events":[],"event_summary":{},"paper_claims":[],"inbound_citations":{"count":0,"internal_anchor_count":0,"sample":[]},"formal_canon":{"evidence_count":0,"sample":[],"anchors":[]},"links":{"html":"https://pith.science/pith/JA4JYCKEJOKEE2CHF4D7DWUIZ3","json":"https://pith.science/pith/JA4JYCKEJOKEE2CHF4D7DWUIZ3.json","graph_json":"https://pith.science/api/pith-number/JA4JYCKEJOKEE2CHF4D7DWUIZ3/graph.json","events_json":"https://pith.science/api/pith-number/JA4JYCKEJOKEE2CHF4D7DWUIZ3/events.json","paper":"https://pith.science/paper/JA4JYCKE"},"agent_actions":{"view_html":"https://pith.science/pith/JA4JYCKEJOKEE2CHF4D7DWUIZ3","download_json":"https://pith.science/pith/JA4JYCKEJOKEE2CHF4D7DWUIZ3.json","view_paper":"https://pith.science/paper/JA4JYCKE","resolve_alias":"https://pith.science/api/pith-number/resolve?arxiv=2208.07500&json=true","fetch_graph":"https://pith.science/api/pith-number/JA4JYCKEJOKEE2CHF4D7DWUIZ3/graph.json","fetch_events":"https://pith.science/api/pith-number/JA4JYCKEJOKEE2CHF4D7DWUIZ3/events.json","actions":{"anchor_timestamp":"https://pith.science/pith/JA4JYCKEJOKEE2CHF4D7DWUIZ3/action/timestamp_anchor","attest_storage":"https://pith.science/pith/JA4JYCKEJOKEE2CHF4D7DWUIZ3/action/storage_attestation","attest_author":"https://pith.science/pith/JA4JYCKEJOKEE2CHF4D7DWUIZ3/action/author_attestation","sign_citation":"https://pith.science/pith/JA4JYCKEJOKEE2CHF4D7DWUIZ3/action/citation_signature","submit_replication":"https://pith.science/pith/JA4JYCKEJOKEE2CHF4D7DWUIZ3/action/replication_record"}},"created_at":"2026-07-05T04:49:05.474089+00:00","updated_at":"2026-07-05T04:49:05.474089+00:00"}