{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2018:JDLHVC7WWTO5O26RPW3AHOU7WK","short_pith_number":"pith:JDLHVC7W","canonical_record":{"source":{"id":"1806.00502","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2018-06-01T18:32:27Z","cross_cats_sorted":["cond-mat.stat-mech","q-bio.CB"],"title_canon_sha256":"cf7af6c2ecff2366488f0da3276ae000135ddad05f94393a69c351b5d1bdb9d9","abstract_canon_sha256":"510e69868400c59a4ba07bdcc817206a39166b72b7eb56766adb5f8ef46df4a2"},"schema_version":"1.0"},"canonical_sha256":"48d67a8bf6b4ddd76bd17db603ba9fb29c663837644876f0a97c773ef0d7c152","source":{"kind":"arxiv","id":"1806.00502","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1806.00502","created_at":"2026-05-17T23:57:07Z"},{"alias_kind":"arxiv_version","alias_value":"1806.00502v1","created_at":"2026-05-17T23:57:07Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1806.00502","created_at":"2026-05-17T23:57:07Z"},{"alias_kind":"pith_short_12","alias_value":"JDLHVC7WWTO5","created_at":"2026-05-18T12:32:31Z"},{"alias_kind":"pith_short_16","alias_value":"JDLHVC7WWTO5O26R","created_at":"2026-05-18T12:32:31Z"},{"alias_kind":"pith_short_8","alias_value":"JDLHVC7W","created_at":"2026-05-18T12:32:31Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2018:JDLHVC7WWTO5O26RPW3AHOU7WK","target":"record","payload":{"canonical_record":{"source":{"id":"1806.00502","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2018-06-01T18:32:27Z","cross_cats_sorted":["cond-mat.stat-mech","q-bio.CB"],"title_canon_sha256":"cf7af6c2ecff2366488f0da3276ae000135ddad05f94393a69c351b5d1bdb9d9","abstract_canon_sha256":"510e69868400c59a4ba07bdcc817206a39166b72b7eb56766adb5f8ef46df4a2"},"schema_version":"1.0"},"canonical_sha256":"48d67a8bf6b4ddd76bd17db603ba9fb29c663837644876f0a97c773ef0d7c152","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-17T23:57:07.525917Z","signature_b64":"qWLsTUU4fHzvbIIwZNjcKjxCj43aDKOHvNykBS7oBieguT3+W3zhUjeyunnPHB8+x77sRRLYle1ZhyZd8903Bg==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"48d67a8bf6b4ddd76bd17db603ba9fb29c663837644876f0a97c773ef0d7c152","last_reissued_at":"2026-05-17T23:57:07.525381Z","signature_status":"signed_v1","first_computed_at":"2026-05-17T23:57:07.525381Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1806.00502","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-17T23:57:07Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"7JEJgz9iBcYqMAoaPDus0YstGolVcMUzoqWRT93lsjvxVNYxfTGUpZ3l6X/Z337YQbKzIDf5O31yLA0rVEAcAA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-27T05:36:21.857006Z"},"content_sha256":"897c72f98318ccd4440df051a90ef3c8e2e57bd3130cf0a31b26a113501a7911","schema_version":"1.0","event_id":"sha256:897c72f98318ccd4440df051a90ef3c8e2e57bd3130cf0a31b26a113501a7911"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2018:JDLHVC7WWTO5O26RPW3AHOU7WK","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Random Walker Models for Durotaxis","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["cond-mat.stat-mech","q-bio.CB"],"primary_cat":"physics.bio-ph","authors_text":"Charles R. Doering, Leonard M. Sander, Xiaoming Mao","submitted_at":"2018-06-01T18:32:27Z","abstract_excerpt":"Motile biological cells in tissue often display the phenomenon of durotaxis, i.e. they tend to move towards stiffer parts of substrate tissue. The mechanism for this behavior is not completely understood. We consider simplified models for durotaxis based on the classic persistent random walker scheme. We show that even a one-dimensional model of this type sheds interesting light on the classes of behavior cells might exhibit. Our results strongly indicate that cells must be able to sense the gradient of stiffness in order to show the effects observed in experiment. This is in contrast to the c"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1806.00502","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-17T23:57:07Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"Y8o+JWWUUaOsQ9E/RbSiQARIPo3+roLXliehvpo2xyltnOsOKHyx16A0JRDthZz+oySn/89GMJLDcIGttV3hAQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-27T05:36:21.857373Z"},"content_sha256":"2a6815627d4b323951eccbfa935a2e004198538b608ba70b8d914571a3ddebb6","schema_version":"1.0","event_id":"sha256:2a6815627d4b323951eccbfa935a2e004198538b608ba70b8d914571a3ddebb6"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/JDLHVC7WWTO5O26RPW3AHOU7WK/bundle.json","state_url":"https://pith.science/pith/JDLHVC7WWTO5O26RPW3AHOU7WK/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/JDLHVC7WWTO5O26RPW3AHOU7WK/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-05-27T05:36:21Z","links":{"resolver":"https://pith.science/pith/JDLHVC7WWTO5O26RPW3AHOU7WK","bundle":"https://pith.science/pith/JDLHVC7WWTO5O26RPW3AHOU7WK/bundle.json","state":"https://pith.science/pith/JDLHVC7WWTO5O26RPW3AHOU7WK/state.json","well_known_bundle":"https://pith.science/.well-known/pith/JDLHVC7WWTO5O26RPW3AHOU7WK/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2018:JDLHVC7WWTO5O26RPW3AHOU7WK","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"510e69868400c59a4ba07bdcc817206a39166b72b7eb56766adb5f8ef46df4a2","cross_cats_sorted":["cond-mat.stat-mech","q-bio.CB"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2018-06-01T18:32:27Z","title_canon_sha256":"cf7af6c2ecff2366488f0da3276ae000135ddad05f94393a69c351b5d1bdb9d9"},"schema_version":"1.0","source":{"id":"1806.00502","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1806.00502","created_at":"2026-05-17T23:57:07Z"},{"alias_kind":"arxiv_version","alias_value":"1806.00502v1","created_at":"2026-05-17T23:57:07Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1806.00502","created_at":"2026-05-17T23:57:07Z"},{"alias_kind":"pith_short_12","alias_value":"JDLHVC7WWTO5","created_at":"2026-05-18T12:32:31Z"},{"alias_kind":"pith_short_16","alias_value":"JDLHVC7WWTO5O26R","created_at":"2026-05-18T12:32:31Z"},{"alias_kind":"pith_short_8","alias_value":"JDLHVC7W","created_at":"2026-05-18T12:32:31Z"}],"graph_snapshots":[{"event_id":"sha256:2a6815627d4b323951eccbfa935a2e004198538b608ba70b8d914571a3ddebb6","target":"graph","created_at":"2026-05-17T23:57:07Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"Motile biological cells in tissue often display the phenomenon of durotaxis, i.e. they tend to move towards stiffer parts of substrate tissue. The mechanism for this behavior is not completely understood. We consider simplified models for durotaxis based on the classic persistent random walker scheme. We show that even a one-dimensional model of this type sheds interesting light on the classes of behavior cells might exhibit. Our results strongly indicate that cells must be able to sense the gradient of stiffness in order to show the effects observed in experiment. This is in contrast to the c","authors_text":"Charles R. Doering, Leonard M. Sander, Xiaoming Mao","cross_cats":["cond-mat.stat-mech","q-bio.CB"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2018-06-01T18:32:27Z","title":"Random Walker Models for Durotaxis"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1806.00502","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:897c72f98318ccd4440df051a90ef3c8e2e57bd3130cf0a31b26a113501a7911","target":"record","created_at":"2026-05-17T23:57:07Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"510e69868400c59a4ba07bdcc817206a39166b72b7eb56766adb5f8ef46df4a2","cross_cats_sorted":["cond-mat.stat-mech","q-bio.CB"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2018-06-01T18:32:27Z","title_canon_sha256":"cf7af6c2ecff2366488f0da3276ae000135ddad05f94393a69c351b5d1bdb9d9"},"schema_version":"1.0","source":{"id":"1806.00502","kind":"arxiv","version":1}},"canonical_sha256":"48d67a8bf6b4ddd76bd17db603ba9fb29c663837644876f0a97c773ef0d7c152","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"48d67a8bf6b4ddd76bd17db603ba9fb29c663837644876f0a97c773ef0d7c152","first_computed_at":"2026-05-17T23:57:07.525381Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-17T23:57:07.525381Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"qWLsTUU4fHzvbIIwZNjcKjxCj43aDKOHvNykBS7oBieguT3+W3zhUjeyunnPHB8+x77sRRLYle1ZhyZd8903Bg==","signature_status":"signed_v1","signed_at":"2026-05-17T23:57:07.525917Z","signed_message":"canonical_sha256_bytes"},"source_id":"1806.00502","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:897c72f98318ccd4440df051a90ef3c8e2e57bd3130cf0a31b26a113501a7911","sha256:2a6815627d4b323951eccbfa935a2e004198538b608ba70b8d914571a3ddebb6"],"state_sha256":"e6e33a58d0fd38c830948c70629c29bae57512940fc2d9c910fe70100f4bd6f8"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"w+oLVLNELzcXJja9+QQL2ZTI0O5lN5TrpNL9gH8/pNJ1n3/NNIdjRC5poMtycHA+eo05qdlhg9eGRtVS+q0hDw==","signed_message":"bundle_sha256_bytes","signed_at":"2026-05-27T05:36:21.859745Z","bundle_sha256":"51284b76fd2e2d9ae8f80319b8aad7bd2a6005190cf6f8d82275caee3ef2b4bf"}}