{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2022:JEUQLHIQSDJEFDWLMASQSR5VHZ","short_pith_number":"pith:JEUQLHIQ","canonical_record":{"source":{"id":"2204.10286","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"q-bio.QM","submitted_at":"2022-04-20T03:55:32Z","cross_cats_sorted":[],"title_canon_sha256":"7bbbacbdd2e79ea4362fb7df0803045a30a0311ad1c0077112fc815286a673cf","abstract_canon_sha256":"ee7413e4d5162f6efb559e66594d2e656b38627ae95fd5f13840ac689f3e1e37"},"schema_version":"1.0"},"canonical_sha256":"4929059d1090d2428ecb60250947b53e5de39c55d5e9510d22892d257c71ca11","source":{"kind":"arxiv","id":"2204.10286","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2204.10286","created_at":"2026-07-05T04:16:48Z"},{"alias_kind":"arxiv_version","alias_value":"2204.10286v1","created_at":"2026-07-05T04:16:48Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2204.10286","created_at":"2026-07-05T04:16:48Z"},{"alias_kind":"pith_short_12","alias_value":"JEUQLHIQSDJE","created_at":"2026-07-05T04:16:48Z"},{"alias_kind":"pith_short_16","alias_value":"JEUQLHIQSDJEFDWL","created_at":"2026-07-05T04:16:48Z"},{"alias_kind":"pith_short_8","alias_value":"JEUQLHIQ","created_at":"2026-07-05T04:16:48Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2022:JEUQLHIQSDJEFDWLMASQSR5VHZ","target":"record","payload":{"canonical_record":{"source":{"id":"2204.10286","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"q-bio.QM","submitted_at":"2022-04-20T03:55:32Z","cross_cats_sorted":[],"title_canon_sha256":"7bbbacbdd2e79ea4362fb7df0803045a30a0311ad1c0077112fc815286a673cf","abstract_canon_sha256":"ee7413e4d5162f6efb559e66594d2e656b38627ae95fd5f13840ac689f3e1e37"},"schema_version":"1.0"},"canonical_sha256":"4929059d1090d2428ecb60250947b53e5de39c55d5e9510d22892d257c71ca11","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-07-05T04:16:48.621372Z","signature_b64":"LkNiDuzX4ysOIzTRIVZ/GN45jPfDRVIyTJMexKJsmqYyTMTetzzAofP99DyYWSgrxB1rPXjfMmaoUvpJmXxsDw==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"4929059d1090d2428ecb60250947b53e5de39c55d5e9510d22892d257c71ca11","last_reissued_at":"2026-07-05T04:16:48.620962Z","signature_status":"signed_v1","first_computed_at":"2026-07-05T04:16:48.620962Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"2204.10286","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T04:16:48Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"qvQ9wvqBD+5BqhOlDREbA2ckGw7HyH00WnSZm1eai+Y2tub9466qyWox5/mDZP4rHzGbpEXSEBLPfaRpRqK7CA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-08T21:42:44.462536Z"},"content_sha256":"783125dccefd6ec4d3b7393dff56bb82e1c63b995cc41320917f3fd1bbb6b5ad","schema_version":"1.0","event_id":"sha256:783125dccefd6ec4d3b7393dff56bb82e1c63b995cc41320917f3fd1bbb6b5ad"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2022:JEUQLHIQSDJEFDWLMASQSR5VHZ","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"ProTranslator: zero-shot protein function prediction using textual description","license":"http://creativecommons.org/licenses/by/4.0/","headline":"","cross_cats":[],"primary_cat":"q-bio.QM","authors_text":"Hanwen Xu, Sheng Wang","submitted_at":"2022-04-20T03:55:32Z","abstract_excerpt":"Accurately finding proteins and genes that have a certain function is the prerequisite for a broad range of biomedical applications. Despite the encouraging progress of existing computational approaches in protein function prediction, it remains challenging to annotate proteins to a novel function that is not collected in the Gene Ontology and does not have any annotated proteins. This limitation, a side effect from the widely-used multi-label classification problem setting of protein function prediction, hampers the progress of studying new pathways and biological processes, and further slows"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2204.10286","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2204.10286/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T04:16:48Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"NVNzZZvGDUpbbOyxvyEzaTWOlLP1cC1MiNbEdqzmjoP33kMHeWPfHZ/rP2UlCcPb0MqGb45kQmEKVjtGYghaCw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-08T21:42:44.463068Z"},"content_sha256":"e9f55f32f4457db497280c37dda477ea7be28f8e51c12e2b76f58a71adfb75f8","schema_version":"1.0","event_id":"sha256:e9f55f32f4457db497280c37dda477ea7be28f8e51c12e2b76f58a71adfb75f8"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/JEUQLHIQSDJEFDWLMASQSR5VHZ/bundle.json","state_url":"https://pith.science/pith/JEUQLHIQSDJEFDWLMASQSR5VHZ/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/JEUQLHIQSDJEFDWLMASQSR5VHZ/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-08-08T21:42:44Z","links":{"resolver":"https://pith.science/pith/JEUQLHIQSDJEFDWLMASQSR5VHZ","bundle":"https://pith.science/pith/JEUQLHIQSDJEFDWLMASQSR5VHZ/bundle.json","state":"https://pith.science/pith/JEUQLHIQSDJEFDWLMASQSR5VHZ/state.json","well_known_bundle":"https://pith.science/.well-known/pith/JEUQLHIQSDJEFDWLMASQSR5VHZ/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2022:JEUQLHIQSDJEFDWLMASQSR5VHZ","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"ee7413e4d5162f6efb559e66594d2e656b38627ae95fd5f13840ac689f3e1e37","cross_cats_sorted":[],"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"q-bio.QM","submitted_at":"2022-04-20T03:55:32Z","title_canon_sha256":"7bbbacbdd2e79ea4362fb7df0803045a30a0311ad1c0077112fc815286a673cf"},"schema_version":"1.0","source":{"id":"2204.10286","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2204.10286","created_at":"2026-07-05T04:16:48Z"},{"alias_kind":"arxiv_version","alias_value":"2204.10286v1","created_at":"2026-07-05T04:16:48Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2204.10286","created_at":"2026-07-05T04:16:48Z"},{"alias_kind":"pith_short_12","alias_value":"JEUQLHIQSDJE","created_at":"2026-07-05T04:16:48Z"},{"alias_kind":"pith_short_16","alias_value":"JEUQLHIQSDJEFDWL","created_at":"2026-07-05T04:16:48Z"},{"alias_kind":"pith_short_8","alias_value":"JEUQLHIQ","created_at":"2026-07-05T04:16:48Z"}],"graph_snapshots":[{"event_id":"sha256:e9f55f32f4457db497280c37dda477ea7be28f8e51c12e2b76f58a71adfb75f8","target":"graph","created_at":"2026-07-05T04:16:48Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2204.10286/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"Accurately finding proteins and genes that have a certain function is the prerequisite for a broad range of biomedical applications. Despite the encouraging progress of existing computational approaches in protein function prediction, it remains challenging to annotate proteins to a novel function that is not collected in the Gene Ontology and does not have any annotated proteins. This limitation, a side effect from the widely-used multi-label classification problem setting of protein function prediction, hampers the progress of studying new pathways and biological processes, and further slows","authors_text":"Hanwen Xu, Sheng Wang","cross_cats":[],"headline":"","license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"q-bio.QM","submitted_at":"2022-04-20T03:55:32Z","title":"ProTranslator: zero-shot protein function prediction using textual description"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2204.10286","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:783125dccefd6ec4d3b7393dff56bb82e1c63b995cc41320917f3fd1bbb6b5ad","target":"record","created_at":"2026-07-05T04:16:48Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"ee7413e4d5162f6efb559e66594d2e656b38627ae95fd5f13840ac689f3e1e37","cross_cats_sorted":[],"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"q-bio.QM","submitted_at":"2022-04-20T03:55:32Z","title_canon_sha256":"7bbbacbdd2e79ea4362fb7df0803045a30a0311ad1c0077112fc815286a673cf"},"schema_version":"1.0","source":{"id":"2204.10286","kind":"arxiv","version":1}},"canonical_sha256":"4929059d1090d2428ecb60250947b53e5de39c55d5e9510d22892d257c71ca11","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"4929059d1090d2428ecb60250947b53e5de39c55d5e9510d22892d257c71ca11","first_computed_at":"2026-07-05T04:16:48.620962Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-05T04:16:48.620962Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"LkNiDuzX4ysOIzTRIVZ/GN45jPfDRVIyTJMexKJsmqYyTMTetzzAofP99DyYWSgrxB1rPXjfMmaoUvpJmXxsDw==","signature_status":"signed_v1","signed_at":"2026-07-05T04:16:48.621372Z","signed_message":"canonical_sha256_bytes"},"source_id":"2204.10286","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:783125dccefd6ec4d3b7393dff56bb82e1c63b995cc41320917f3fd1bbb6b5ad","sha256:e9f55f32f4457db497280c37dda477ea7be28f8e51c12e2b76f58a71adfb75f8"],"state_sha256":"80bfd0f01cbc706a84ecb5dbe63058e306093f3d7af4bd88979dc1f8b13fc4e5"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"RD1D4AIeNBD2M3tOZkt2tzBK94eE3Ox4o4GMpCQf7ew4Yi8lf6zkG/zn00ZvLVv6i60bG/B/XtE22jwflmnrAQ==","signed_message":"bundle_sha256_bytes","signed_at":"2026-08-08T21:42:44.468052Z","bundle_sha256":"b1e91254e7dd9771c7f6647541891468d07f6e2c05649ca2dcbc3f502335a27a"}}