{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2016:JH4QHSHKJS2FTEWTANRJLOL3TN","short_pith_number":"pith:JH4QHSHK","canonical_record":{"source":{"id":"1604.00087","kind":"arxiv","version":2},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.NC","submitted_at":"2016-04-01T00:30:01Z","cross_cats_sorted":[],"title_canon_sha256":"fd638f8b5c008707ae56a06b65d8861f476b4d833ceae4fadcae5221f8524756","abstract_canon_sha256":"aad60d86fe5644eec47c83bd0bb4598b857cecbdd6a46f44117c4dff89b4e113"},"schema_version":"1.0"},"canonical_sha256":"49f903c8ea4cb45992d3036295b97b9b43ca051e0bf150393cbba2be00c4c253","source":{"kind":"arxiv","id":"1604.00087","version":2},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1604.00087","created_at":"2026-05-18T00:47:37Z"},{"alias_kind":"arxiv_version","alias_value":"1604.00087v2","created_at":"2026-05-18T00:47:37Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1604.00087","created_at":"2026-05-18T00:47:37Z"},{"alias_kind":"pith_short_12","alias_value":"JH4QHSHKJS2F","created_at":"2026-05-18T12:30:25Z"},{"alias_kind":"pith_short_16","alias_value":"JH4QHSHKJS2FTEWT","created_at":"2026-05-18T12:30:25Z"},{"alias_kind":"pith_short_8","alias_value":"JH4QHSHK","created_at":"2026-05-18T12:30:25Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2016:JH4QHSHKJS2FTEWTANRJLOL3TN","target":"record","payload":{"canonical_record":{"source":{"id":"1604.00087","kind":"arxiv","version":2},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.NC","submitted_at":"2016-04-01T00:30:01Z","cross_cats_sorted":[],"title_canon_sha256":"fd638f8b5c008707ae56a06b65d8861f476b4d833ceae4fadcae5221f8524756","abstract_canon_sha256":"aad60d86fe5644eec47c83bd0bb4598b857cecbdd6a46f44117c4dff89b4e113"},"schema_version":"1.0"},"canonical_sha256":"49f903c8ea4cb45992d3036295b97b9b43ca051e0bf150393cbba2be00c4c253","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T00:47:37.020364Z","signature_b64":"aa2CkORAUAIlp1pesWOjYv7As6qoYmT4BK+yXVYVUMe2GTGAPex3gH3Q4pRuQDMYmKQl26Pdl2LeYNdHrxyTCA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"49f903c8ea4cb45992d3036295b97b9b43ca051e0bf150393cbba2be00c4c253","last_reissued_at":"2026-05-18T00:47:37.019881Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T00:47:37.019881Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1604.00087","source_version":2,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T00:47:37Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"Su6oXTiDU/W1Bxmc6I0+d/rld5uw986PjA6LRTEbrpjaQVZl+tJ2kkL3R1v7QU1ZDwYofV0Atxf2iHWWS73UDQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-25T10:22:49.768676Z"},"content_sha256":"07fe00f561d8ee7c7486431f89a31cd7dff4df5729e9a80f95bdb3e6094f01b6","schema_version":"1.0","event_id":"sha256:07fe00f561d8ee7c7486431f89a31cd7dff4df5729e9a80f95bdb3e6094f01b6"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2016:JH4QHSHKJS2FTEWTANRJLOL3TN","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Automated point-neuron simplification of data-driven microcircuit models","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"q-bio.NC","authors_text":"Andrew P. Davison, Christian Pozzorini, Christian R\\\"ossert, Csaba Eroe, Eilif Muller, Giuseppe Chindemi, Henry Markram, Idan Segev, James King, Marc-Oliver Gewaltig, Max Nolte, Michael W. Reimann, Srikanth Ramaswamy, Taylor H. Newton, Willem Wybo, Wulfram Gerstner","submitted_at":"2016-04-01T00:30:01Z","abstract_excerpt":"A method is presented for the reduction of morphologically detailed microcircuit models to a point-neuron representation without human intervention. The simplification occurs in a modular workflow, in the neighborhood of a user specified network activity state for the reference model, the \"operating point\". First, synapses are moved to the soma, correcting for dendritic filtering by low-pass filtering the delivered synaptic current. Filter parameters are computed numerically and independently for inhibitory and excitatory input using a Green's function approach. Next, point-neuron models for e"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1604.00087","kind":"arxiv","version":2},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T00:47:37Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"B+gVkCEOB+LjjRK1EqfRBhTaQfg8FLafa7uHTl+1WOcpj0p8nYrGRi/pu4wz8dzFXQNmpCmTA0Maie7ytif+DQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-25T10:22:49.769361Z"},"content_sha256":"ef4730f65c219ab5535879458a92025b9ce694eb3569d69eeb9d4b87f04c4021","schema_version":"1.0","event_id":"sha256:ef4730f65c219ab5535879458a92025b9ce694eb3569d69eeb9d4b87f04c4021"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/JH4QHSHKJS2FTEWTANRJLOL3TN/bundle.json","state_url":"https://pith.science/pith/JH4QHSHKJS2FTEWTANRJLOL3TN/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/JH4QHSHKJS2FTEWTANRJLOL3TN/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-05-25T10:22:49Z","links":{"resolver":"https://pith.science/pith/JH4QHSHKJS2FTEWTANRJLOL3TN","bundle":"https://pith.science/pith/JH4QHSHKJS2FTEWTANRJLOL3TN/bundle.json","state":"https://pith.science/pith/JH4QHSHKJS2FTEWTANRJLOL3TN/state.json","well_known_bundle":"https://pith.science/.well-known/pith/JH4QHSHKJS2FTEWTANRJLOL3TN/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2016:JH4QHSHKJS2FTEWTANRJLOL3TN","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"aad60d86fe5644eec47c83bd0bb4598b857cecbdd6a46f44117c4dff89b4e113","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.NC","submitted_at":"2016-04-01T00:30:01Z","title_canon_sha256":"fd638f8b5c008707ae56a06b65d8861f476b4d833ceae4fadcae5221f8524756"},"schema_version":"1.0","source":{"id":"1604.00087","kind":"arxiv","version":2}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1604.00087","created_at":"2026-05-18T00:47:37Z"},{"alias_kind":"arxiv_version","alias_value":"1604.00087v2","created_at":"2026-05-18T00:47:37Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1604.00087","created_at":"2026-05-18T00:47:37Z"},{"alias_kind":"pith_short_12","alias_value":"JH4QHSHKJS2F","created_at":"2026-05-18T12:30:25Z"},{"alias_kind":"pith_short_16","alias_value":"JH4QHSHKJS2FTEWT","created_at":"2026-05-18T12:30:25Z"},{"alias_kind":"pith_short_8","alias_value":"JH4QHSHK","created_at":"2026-05-18T12:30:25Z"}],"graph_snapshots":[{"event_id":"sha256:ef4730f65c219ab5535879458a92025b9ce694eb3569d69eeb9d4b87f04c4021","target":"graph","created_at":"2026-05-18T00:47:37Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"A method is presented for the reduction of morphologically detailed microcircuit models to a point-neuron representation without human intervention. The simplification occurs in a modular workflow, in the neighborhood of a user specified network activity state for the reference model, the \"operating point\". First, synapses are moved to the soma, correcting for dendritic filtering by low-pass filtering the delivered synaptic current. Filter parameters are computed numerically and independently for inhibitory and excitatory input using a Green's function approach. Next, point-neuron models for e","authors_text":"Andrew P. Davison, Christian Pozzorini, Christian R\\\"ossert, Csaba Eroe, Eilif Muller, Giuseppe Chindemi, Henry Markram, Idan Segev, James King, Marc-Oliver Gewaltig, Max Nolte, Michael W. Reimann, Srikanth Ramaswamy, Taylor H. Newton, Willem Wybo, Wulfram Gerstner","cross_cats":[],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.NC","submitted_at":"2016-04-01T00:30:01Z","title":"Automated point-neuron simplification of data-driven microcircuit models"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1604.00087","kind":"arxiv","version":2},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:07fe00f561d8ee7c7486431f89a31cd7dff4df5729e9a80f95bdb3e6094f01b6","target":"record","created_at":"2026-05-18T00:47:37Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"aad60d86fe5644eec47c83bd0bb4598b857cecbdd6a46f44117c4dff89b4e113","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.NC","submitted_at":"2016-04-01T00:30:01Z","title_canon_sha256":"fd638f8b5c008707ae56a06b65d8861f476b4d833ceae4fadcae5221f8524756"},"schema_version":"1.0","source":{"id":"1604.00087","kind":"arxiv","version":2}},"canonical_sha256":"49f903c8ea4cb45992d3036295b97b9b43ca051e0bf150393cbba2be00c4c253","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"49f903c8ea4cb45992d3036295b97b9b43ca051e0bf150393cbba2be00c4c253","first_computed_at":"2026-05-18T00:47:37.019881Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T00:47:37.019881Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"aa2CkORAUAIlp1pesWOjYv7As6qoYmT4BK+yXVYVUMe2GTGAPex3gH3Q4pRuQDMYmKQl26Pdl2LeYNdHrxyTCA==","signature_status":"signed_v1","signed_at":"2026-05-18T00:47:37.020364Z","signed_message":"canonical_sha256_bytes"},"source_id":"1604.00087","source_kind":"arxiv","source_version":2}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:07fe00f561d8ee7c7486431f89a31cd7dff4df5729e9a80f95bdb3e6094f01b6","sha256:ef4730f65c219ab5535879458a92025b9ce694eb3569d69eeb9d4b87f04c4021"],"state_sha256":"53f96cee882ca56c3effc9a7f34c3ad7c63357e79eacb2d720e2fabbe475f537"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"tZTOD4b9scdkc2yNNvCaGDJQBK1bjeQj+JId4TtOtvPQMmHS5I5+AqQaHdd9xMu71rkS0i9DZGR9YAJmCnwFAw==","signed_message":"bundle_sha256_bytes","signed_at":"2026-05-25T10:22:49.772663Z","bundle_sha256":"88d825239dc1be30ebac667d6ff2275a09015e6d9b809d3f280f355929135eac"}}