{"record_type":"pith_number_record","schema_url":"https://pith.science/schemas/pith-number/v1.json","pith_number":"pith:2015:JUY4PSMBA46QAK743BHHLJMCOO","short_pith_number":"pith:JUY4PSMB","schema_version":"1.0","canonical_sha256":"4d31c7c981073d002bfcd84e75a58273937a07a3b32622fdb85484c1e1daad0c","source":{"kind":"arxiv","id":"1506.01089","version":2},"attestation_state":"computed","paper":{"title":"Confinement-induced glassy dynamics in a model for chromosome organization","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["physics.bio-ph","q-bio.BM"],"primary_cat":"cond-mat.soft","authors_text":"Changbong Hyeon, D. Thirumalai, Hongsuk Kang, Young-Gui Yoon","submitted_at":"2015-06-03T00:18:55Z","abstract_excerpt":"Recent experiments showing scaling of the intrachromosomal contact probability, $P(s)\\sim s^{-1}$ with the genomic distance $s$, are interpreted to mean a self-similar fractal-like chromosome organization. However, scaling of $P(s)$ varies across organisms, requiring an explanation. We illustrate dynamical arrest in a highly confined space as a discriminating marker for genome organization, by modeling chromosome inside a nucleus as a homopolymer confined to a sphere of varying sizes. Brownian dynamics simulations show that the chain dynamics slows down as the polymer volume fraction ($\\phi$) "},"verification_status":{"content_addressed":true,"pith_receipt":true,"author_attested":false,"weak_author_claims":0,"strong_author_claims":0,"externally_anchored":false,"storage_verified":false,"citation_signatures":0,"replication_records":0,"graph_snapshot":true,"references_resolved":false,"formal_links_present":false},"canonical_record":{"source":{"id":"1506.01089","kind":"arxiv","version":2},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cond-mat.soft","submitted_at":"2015-06-03T00:18:55Z","cross_cats_sorted":["physics.bio-ph","q-bio.BM"],"title_canon_sha256":"f144f85fd9f7f5791485f10ddda373d361db6a577376919e97465daa699b4d08","abstract_canon_sha256":"fde89097577e20faf4a9d233c5f66fb5f7924491d58355f0ad2723538dd3d41a"},"schema_version":"1.0"},"receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T00:54:03.856227Z","signature_b64":"OEmhZ2XJtrD537uCbBlyb582S4i9hLCZQ3LMY0Q9zqslojRUZqMtFvNGkkH73Bea2qHsJwNuxk+w00O9nd58CQ==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"4d31c7c981073d002bfcd84e75a58273937a07a3b32622fdb85484c1e1daad0c","last_reissued_at":"2026-05-18T00:54:03.855874Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T00:54:03.855874Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"graph_snapshot":{"paper":{"title":"Confinement-induced glassy dynamics in a model for chromosome organization","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["physics.bio-ph","q-bio.BM"],"primary_cat":"cond-mat.soft","authors_text":"Changbong Hyeon, D. Thirumalai, Hongsuk Kang, Young-Gui Yoon","submitted_at":"2015-06-03T00:18:55Z","abstract_excerpt":"Recent experiments showing scaling of the intrachromosomal contact probability, $P(s)\\sim s^{-1}$ with the genomic distance $s$, are interpreted to mean a self-similar fractal-like chromosome organization. However, scaling of $P(s)$ varies across organisms, requiring an explanation. We illustrate dynamical arrest in a highly confined space as a discriminating marker for genome organization, by modeling chromosome inside a nucleus as a homopolymer confined to a sphere of varying sizes. Brownian dynamics simulations show that the chain dynamics slows down as the polymer volume fraction ($\\phi$) "},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1506.01089","kind":"arxiv","version":2},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"aliases":[{"alias_kind":"arxiv","alias_value":"1506.01089","created_at":"2026-05-18T00:54:03.855929+00:00"},{"alias_kind":"arxiv_version","alias_value":"1506.01089v2","created_at":"2026-05-18T00:54:03.855929+00:00"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1506.01089","created_at":"2026-05-18T00:54:03.855929+00:00"},{"alias_kind":"pith_short_12","alias_value":"JUY4PSMBA46Q","created_at":"2026-05-18T12:29:27.538025+00:00"},{"alias_kind":"pith_short_16","alias_value":"JUY4PSMBA46QAK74","created_at":"2026-05-18T12:29:27.538025+00:00"},{"alias_kind":"pith_short_8","alias_value":"JUY4PSMB","created_at":"2026-05-18T12:29:27.538025+00:00"}],"events":[],"event_summary":{},"paper_claims":[],"inbound_citations":{"count":0,"internal_anchor_count":0,"sample":[]},"formal_canon":{"evidence_count":0,"sample":[],"anchors":[]},"links":{"html":"https://pith.science/pith/JUY4PSMBA46QAK743BHHLJMCOO","json":"https://pith.science/pith/JUY4PSMBA46QAK743BHHLJMCOO.json","graph_json":"https://pith.science/api/pith-number/JUY4PSMBA46QAK743BHHLJMCOO/graph.json","events_json":"https://pith.science/api/pith-number/JUY4PSMBA46QAK743BHHLJMCOO/events.json","paper":"https://pith.science/paper/JUY4PSMB"},"agent_actions":{"view_html":"https://pith.science/pith/JUY4PSMBA46QAK743BHHLJMCOO","download_json":"https://pith.science/pith/JUY4PSMBA46QAK743BHHLJMCOO.json","view_paper":"https://pith.science/paper/JUY4PSMB","resolve_alias":"https://pith.science/api/pith-number/resolve?arxiv=1506.01089&json=true","fetch_graph":"https://pith.science/api/pith-number/JUY4PSMBA46QAK743BHHLJMCOO/graph.json","fetch_events":"https://pith.science/api/pith-number/JUY4PSMBA46QAK743BHHLJMCOO/events.json","actions":{"anchor_timestamp":"https://pith.science/pith/JUY4PSMBA46QAK743BHHLJMCOO/action/timestamp_anchor","attest_storage":"https://pith.science/pith/JUY4PSMBA46QAK743BHHLJMCOO/action/storage_attestation","attest_author":"https://pith.science/pith/JUY4PSMBA46QAK743BHHLJMCOO/action/author_attestation","sign_citation":"https://pith.science/pith/JUY4PSMBA46QAK743BHHLJMCOO/action/citation_signature","submit_replication":"https://pith.science/pith/JUY4PSMBA46QAK743BHHLJMCOO/action/replication_record"}},"created_at":"2026-05-18T00:54:03.855929+00:00","updated_at":"2026-05-18T00:54:03.855929+00:00"}