{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2023:KAZH76TNXUQGQHSNEVONDNIUQO","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"b2f40d1dbd351e3aedd931a1db1dc10be4d81e5fb382fd25188f9f6051feca54","cross_cats_sorted":["physics.bio-ph"],"license":"http://creativecommons.org/licenses/by-nc-nd/4.0/","primary_cat":"q-bio.CB","submitted_at":"2023-09-28T15:06:36Z","title_canon_sha256":"a8b1fb08e16f1de94286fb54789abf784c921fe8875bb41996b25e152c618e6a"},"schema_version":"1.0","source":{"id":"2309.16498","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2309.16498","created_at":"2026-07-05T06:55:17Z"},{"alias_kind":"arxiv_version","alias_value":"2309.16498v1","created_at":"2026-07-05T06:55:17Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2309.16498","created_at":"2026-07-05T06:55:17Z"},{"alias_kind":"pith_short_12","alias_value":"KAZH76TNXUQG","created_at":"2026-07-05T06:55:17Z"},{"alias_kind":"pith_short_16","alias_value":"KAZH76TNXUQGQHSN","created_at":"2026-07-05T06:55:17Z"},{"alias_kind":"pith_short_8","alias_value":"KAZH76TN","created_at":"2026-07-05T06:55:17Z"}],"graph_snapshots":[{"event_id":"sha256:8199e69bee1087e8c4ba303344d8ddfa5d4b453a8df00b47eb6e2d2279fb8a3b","target":"graph","created_at":"2026-07-05T06:55:17Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2309.16498/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"Cell shape has long been used to discern cell phenotypes and states, but the underlying premise has not been quantitatively tested. Here, we show that a single cell image can be used to discriminate its migration behavior by analyzing a large number of cell migration data in vitro. We analyzed a large number of two-dimensional cell migration images over time and found that the cell shape variation space has only six dimensions, and migration behavior can be determined by the coordinates of a single cell image in this 6-dimensional shape-space. We further show that this is possible because pers","authors_text":"Kuangcai Chen, Ning Fang, Xiuxiu He, Yi Jiang","cross_cats":["physics.bio-ph"],"headline":"","license":"http://creativecommons.org/licenses/by-nc-nd/4.0/","primary_cat":"q-bio.CB","submitted_at":"2023-09-28T15:06:36Z","title":"Coordinates in low-dimensional cell shape-space discriminate migration dynamics from single static cell images"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2309.16498","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:3167d34d851ef1b72afba1fa70b3304f6ba0bdb160fc5c239e1eb61a065be8de","target":"record","created_at":"2026-07-05T06:55:17Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"b2f40d1dbd351e3aedd931a1db1dc10be4d81e5fb382fd25188f9f6051feca54","cross_cats_sorted":["physics.bio-ph"],"license":"http://creativecommons.org/licenses/by-nc-nd/4.0/","primary_cat":"q-bio.CB","submitted_at":"2023-09-28T15:06:36Z","title_canon_sha256":"a8b1fb08e16f1de94286fb54789abf784c921fe8875bb41996b25e152c618e6a"},"schema_version":"1.0","source":{"id":"2309.16498","kind":"arxiv","version":1}},"canonical_sha256":"50327ffa6dbd20681e4d255cd1b51483856dedfbf0b74d0563de00420763ee43","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"50327ffa6dbd20681e4d255cd1b51483856dedfbf0b74d0563de00420763ee43","first_computed_at":"2026-07-05T06:55:17.575350Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-05T06:55:17.575350Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"injn0C5yrBP3G36lBwpDg6NT1Ie4XocMyZaBLe3WlFSrDSUd+35R2VNvo9u4o7nhud0UQaPsV5X475rCgW6JCA==","signature_status":"signed_v1","signed_at":"2026-07-05T06:55:17.575893Z","signed_message":"canonical_sha256_bytes"},"source_id":"2309.16498","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:3167d34d851ef1b72afba1fa70b3304f6ba0bdb160fc5c239e1eb61a065be8de","sha256:8199e69bee1087e8c4ba303344d8ddfa5d4b453a8df00b47eb6e2d2279fb8a3b"],"state_sha256":"4aeac05744884ace044b578d516c90029b271eae256b0ce65cd8e434ef9bb269"}