{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2023:KWID4YGHZFMYFIZ7NX55GSEGWC","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"640617aadd5d8322c6ce1f03e6f5305487c341ca6b429860bfbcfa894c992256","cross_cats_sorted":["cs.CV","cs.LG","q-bio.GN"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2023-06-15T16:13:52Z","title_canon_sha256":"24598f99c7fc3a03e2e3aed32f66285125e5caa583142555da35b5e9f2fa1c2c"},"schema_version":"1.0","source":{"id":"2306.09391","kind":"arxiv","version":3}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2306.09391","created_at":"2026-07-05T08:21:05Z"},{"alias_kind":"arxiv_version","alias_value":"2306.09391v3","created_at":"2026-07-05T08:21:05Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2306.09391","created_at":"2026-07-05T08:21:05Z"},{"alias_kind":"pith_short_12","alias_value":"KWID4YGHZFMY","created_at":"2026-07-05T08:21:05Z"},{"alias_kind":"pith_short_16","alias_value":"KWID4YGHZFMYFIZ7","created_at":"2026-07-05T08:21:05Z"},{"alias_kind":"pith_short_8","alias_value":"KWID4YGH","created_at":"2026-07-05T08:21:05Z"}],"graph_snapshots":[{"event_id":"sha256:f9a8d88e3720107a7b8a9eb2bc719e6c234323c93ce1f121fd63fc38a8b6ff4e","target":"graph","created_at":"2026-07-05T08:21:05Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2306.09391/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"High-content cellular imaging, transcriptomics, and proteomics data provide rich and complementary views on the molecular layers of biology that influence cellular states and function. However, the biological determinants through which changes in multi-omics measurements influence cellular morphology have not yet been systematically explored, and the degree to which cell imaging could potentially enable the prediction of multi-omics directly from cell imaging data is therefore currently unclear. Here, we address the question of whether it is possible to predict bulk multi-omics measurements di","authors_text":"Arash Mehrjou, Benedetta Carbone, Carl Fishwick, Cuong Nguyen, Hakan Keles, Jing Bi, Johanna Vappiani, Marcus Bantscheff, Maryana Alegro, Patrick Schwab, Rahil Mehrizi, Siobhan Sanford, Yi Zhao","cross_cats":["cs.CV","cs.LG","q-bio.GN"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2023-06-15T16:13:52Z","title":"Multi-omics Prediction from High-content Cellular Imaging with Deep Learning"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2306.09391","kind":"arxiv","version":3},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:187516d5d5225479ba02dfcd4522698d041069081765d528cb6477ce7e490448","target":"record","created_at":"2026-07-05T08:21:05Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"640617aadd5d8322c6ce1f03e6f5305487c341ca6b429860bfbcfa894c992256","cross_cats_sorted":["cs.CV","cs.LG","q-bio.GN"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2023-06-15T16:13:52Z","title_canon_sha256":"24598f99c7fc3a03e2e3aed32f66285125e5caa583142555da35b5e9f2fa1c2c"},"schema_version":"1.0","source":{"id":"2306.09391","kind":"arxiv","version":3}},"canonical_sha256":"55903e60c7c95982a33f6dfbd34886b089e2d81f806640b1b7f0858c3cacd97f","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"55903e60c7c95982a33f6dfbd34886b089e2d81f806640b1b7f0858c3cacd97f","first_computed_at":"2026-07-05T08:21:05.347992Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-05T08:21:05.347992Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"Vwi9DsdKI5twyiTfiT0klZxgAP9YGR2cwQ+xEa4ZteB6dB4nq6n9fLzcZFIL+po0ZgBnHXR26mcKcTxTISVwDg==","signature_status":"signed_v1","signed_at":"2026-07-05T08:21:05.348515Z","signed_message":"canonical_sha256_bytes"},"source_id":"2306.09391","source_kind":"arxiv","source_version":3}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:187516d5d5225479ba02dfcd4522698d041069081765d528cb6477ce7e490448","sha256:f9a8d88e3720107a7b8a9eb2bc719e6c234323c93ce1f121fd63fc38a8b6ff4e"],"state_sha256":"4f686b3c56b84a99aa33af91cd95913cd4534cc28803f914ec9c0809e339c4c3"}