{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2019:L2AHXWOUTILQCMLHE4VWIOXCNO","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"17980455d12ec84a497086711a6ad860d181673d0b4b2b9739ad041cd7e779ef","cross_cats_sorted":["cond-mat.soft","q-bio.CB"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2019-08-10T10:45:15Z","title_canon_sha256":"1d0901faccc3042dd239e17aa5caac2b31187b4a5c77bf0c1d069a051f67a7a5"},"schema_version":"1.0","source":{"id":"1908.03725","kind":"arxiv","version":2}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1908.03725","created_at":"2026-07-05T01:23:09Z"},{"alias_kind":"arxiv_version","alias_value":"1908.03725v2","created_at":"2026-07-05T01:23:09Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1908.03725","created_at":"2026-07-05T01:23:09Z"},{"alias_kind":"pith_short_12","alias_value":"L2AHXWOUTILQ","created_at":"2026-07-05T01:23:09Z"},{"alias_kind":"pith_short_16","alias_value":"L2AHXWOUTILQCMLH","created_at":"2026-07-05T01:23:09Z"},{"alias_kind":"pith_short_8","alias_value":"L2AHXWOU","created_at":"2026-07-05T01:23:09Z"}],"graph_snapshots":[{"event_id":"sha256:2c0bc6ecd1b10849b9b72a6476a95813a3e71df1382ffbe021c878a097c8ac0f","target":"graph","created_at":"2026-07-05T01:23:09Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/1908.03725/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"Both animal and plant tissue exhibit a nonlinear rheological phenomenon known as compression stiffening, or an increase in moduli with increasing uniaxial compressive strain. Does such a phenomenon exist in single cells, which are the building blocks of tissues? One expects an individual cell to compression soften since the semiflexible biopolymer-based cytoskeletal network maintains the mechanical integrity of the cell and in vitro semiflexible biopolymer networks typically compression soften. To the contrary, we find that mouse embryonic fibroblasts (mEFs) compression stiffen under uniaxial ","authors_text":"A. E. Patteson, Anne van Oosten, J. M. Schwarz, Katarzyna Pogoda, M. C. Gandikota, P. A. Janmey, T. A. Engstrom","cross_cats":["cond-mat.soft","q-bio.CB"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2019-08-10T10:45:15Z","title":"Loops versus lines and the compression stiffening of cells"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1908.03725","kind":"arxiv","version":2},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:74c7ab4646174e78ef3c199dbc8f7a5d2f50c259eb7cb062886352a2abc04648","target":"record","created_at":"2026-07-05T01:23:09Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"17980455d12ec84a497086711a6ad860d181673d0b4b2b9739ad041cd7e779ef","cross_cats_sorted":["cond-mat.soft","q-bio.CB"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2019-08-10T10:45:15Z","title_canon_sha256":"1d0901faccc3042dd239e17aa5caac2b31187b4a5c77bf0c1d069a051f67a7a5"},"schema_version":"1.0","source":{"id":"1908.03725","kind":"arxiv","version":2}},"canonical_sha256":"5e807bd9d49a17013167272b643ae26b9635c1d32d7d4242191d1a248143d40c","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"5e807bd9d49a17013167272b643ae26b9635c1d32d7d4242191d1a248143d40c","first_computed_at":"2026-07-05T01:23:09.088555Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-05T01:23:09.088555Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"draoc7879GtZHZwzxbGGD1RQGmKPx3i9JPV4u4q009HD9KIL/MlTn7z7jvT1xmZs6zm/7ELjJkiH2BsACkWlCg==","signature_status":"signed_v1","signed_at":"2026-07-05T01:23:09.089005Z","signed_message":"canonical_sha256_bytes"},"source_id":"1908.03725","source_kind":"arxiv","source_version":2}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:74c7ab4646174e78ef3c199dbc8f7a5d2f50c259eb7cb062886352a2abc04648","sha256:2c0bc6ecd1b10849b9b72a6476a95813a3e71df1382ffbe021c878a097c8ac0f"],"state_sha256":"ce6230f1561e8f5c9844c620db4065c35e00552ae0ec9501435eaf406fd36ad3"}