{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2016:LGMT3374Z3FK5DJPJGSLYKXZN7","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"d6daf1d255c4b426f40f42d36d885528e5c31675872656859128ec9b4af8513b","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.NC","submitted_at":"2016-03-07T08:11:19Z","title_canon_sha256":"6830d8366d90fd611585b3905a6f66e383cf55fa076efd85c14c67e5f7791329"},"schema_version":"1.0","source":{"id":"1603.01970","kind":"arxiv","version":2}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1603.01970","created_at":"2026-05-18T01:10:42Z"},{"alias_kind":"arxiv_version","alias_value":"1603.01970v2","created_at":"2026-05-18T01:10:42Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1603.01970","created_at":"2026-05-18T01:10:42Z"},{"alias_kind":"pith_short_12","alias_value":"LGMT3374Z3FK","created_at":"2026-05-18T12:30:29Z"},{"alias_kind":"pith_short_16","alias_value":"LGMT3374Z3FK5DJP","created_at":"2026-05-18T12:30:29Z"},{"alias_kind":"pith_short_8","alias_value":"LGMT3374","created_at":"2026-05-18T12:30:29Z"}],"graph_snapshots":[{"event_id":"sha256:f1a4abe91447236b4af2bec8e0afe57f2e40224f5bfe7fffc860b091dbcc3fe6","target":"graph","created_at":"2026-05-18T01:10:42Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"Emergence and maintenance of excitability is often phrased in terms of arriving at and remaining about a manifold of 'solutions' embedded in a high dimensional parameter space. Alongside studies that extend traditional focus on control-based regulation of structural parameters (channel densities), there is a budding interest in self-organization of kinetic parameters. In this picture, ionic channels are continually forced by activity in-and-out of a large pool of states not available for the mechanism of excitability. The process, acting on expressed structure, provides a bed for generation of","authors_text":"Shimon Marom","cross_cats":[],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.NC","submitted_at":"2016-03-07T08:11:19Z","title":"Emergence and Maintenance of Excitability: Kinetics over Structure"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1603.01970","kind":"arxiv","version":2},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:cacb51ca05ae225dd1193289b3375a55b55cd177f1aa8280cd879dd653c447f5","target":"record","created_at":"2026-05-18T01:10:42Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"d6daf1d255c4b426f40f42d36d885528e5c31675872656859128ec9b4af8513b","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.NC","submitted_at":"2016-03-07T08:11:19Z","title_canon_sha256":"6830d8366d90fd611585b3905a6f66e383cf55fa076efd85c14c67e5f7791329"},"schema_version":"1.0","source":{"id":"1603.01970","kind":"arxiv","version":2}},"canonical_sha256":"59993deffccecaae8d2f49a4bc2af96ff4c23f661d1bc2d734916bce1eeb34bd","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"59993deffccecaae8d2f49a4bc2af96ff4c23f661d1bc2d734916bce1eeb34bd","first_computed_at":"2026-05-18T01:10:42.754268Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T01:10:42.754268Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"ZoLPwOUrjRfGLNxVKHX8raayRLnpqEyrlJjBSyIifJdxEyQ2WJgfckyKtvugsLuLnalOxjItFgLOZ0evkaToCQ==","signature_status":"signed_v1","signed_at":"2026-05-18T01:10:42.754688Z","signed_message":"canonical_sha256_bytes"},"source_id":"1603.01970","source_kind":"arxiv","source_version":2}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:cacb51ca05ae225dd1193289b3375a55b55cd177f1aa8280cd879dd653c447f5","sha256:f1a4abe91447236b4af2bec8e0afe57f2e40224f5bfe7fffc860b091dbcc3fe6"],"state_sha256":"37421a3b61b86925b61c404d1e5f10992b74ce7107080f1fd0fdfc928628f8fd"}