{"record_type":"pith_number_record","schema_url":"https://pith.science/schemas/pith-number/v1.json","pith_number":"pith:2014:LTAJAWBGKDBTFARDTF3DRBLUD7","short_pith_number":"pith:LTAJAWBG","schema_version":"1.0","canonical_sha256":"5cc090582650c332822399763885741fcfe96e5cf40291995a6cbec6a69e2f3c","source":{"kind":"arxiv","id":"1403.4086","version":3},"attestation_state":"computed","paper":{"title":"Gaussian process test for high-throughput sequencing time series: application to experimental evolution","license":"http://creativecommons.org/licenses/by/3.0/","headline":"","cross_cats":["q-bio.GN","q-bio.QM","stat.AP"],"primary_cat":"q-bio.PE","authors_text":"\\'Agnes J\\'on\\'as, Antti Honkela, Carolin Kosiol, Hande Topa, Robert Kofler","submitted_at":"2014-03-17T13:08:06Z","abstract_excerpt":"Motivation: Recent advances in high-throughput sequencing (HTS) have made it possible to monitor genomes in great detail. New experiments not only use HTS to measure genomic features at one time point but to monitor them changing over time with the aim of identifying significant changes in their abundance. In population genetics, for example, allele frequencies are monitored over time to detect significant frequency changes that indicate selection pressures. Previous attempts at analysing data from HTS experiments have been limited as they could not simultaneously include data at intermediate "},"verification_status":{"content_addressed":true,"pith_receipt":true,"author_attested":false,"weak_author_claims":0,"strong_author_claims":0,"externally_anchored":false,"storage_verified":false,"citation_signatures":0,"replication_records":0,"graph_snapshot":true,"references_resolved":false,"formal_links_present":false},"canonical_record":{"source":{"id":"1403.4086","kind":"arxiv","version":3},"metadata":{"license":"http://creativecommons.org/licenses/by/3.0/","primary_cat":"q-bio.PE","submitted_at":"2014-03-17T13:08:06Z","cross_cats_sorted":["q-bio.GN","q-bio.QM","stat.AP"],"title_canon_sha256":"aebbd05392ecbf7a12637c99f58f104833696b015ed9bf6b81b00b8f6bafd2f5","abstract_canon_sha256":"30998f13700f175eb9ea06cbf51cee2a4d6fdde35943c15f9d9fcfd94e3148e4"},"schema_version":"1.0"},"receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T02:42:37.163513Z","signature_b64":"Z+uLNrC2ASK1HBfn4dTuolEd5+l0bnCsZ5/xbvV5rab/rrWOl7kpPt/ZTZOVMytxQy2lq9EQfzqgcV+mVFjZBA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"5cc090582650c332822399763885741fcfe96e5cf40291995a6cbec6a69e2f3c","last_reissued_at":"2026-05-18T02:42:37.162874Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T02:42:37.162874Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"graph_snapshot":{"paper":{"title":"Gaussian process test for high-throughput sequencing time series: application to experimental evolution","license":"http://creativecommons.org/licenses/by/3.0/","headline":"","cross_cats":["q-bio.GN","q-bio.QM","stat.AP"],"primary_cat":"q-bio.PE","authors_text":"\\'Agnes J\\'on\\'as, Antti Honkela, Carolin Kosiol, Hande Topa, Robert Kofler","submitted_at":"2014-03-17T13:08:06Z","abstract_excerpt":"Motivation: Recent advances in high-throughput sequencing (HTS) have made it possible to monitor genomes in great detail. New experiments not only use HTS to measure genomic features at one time point but to monitor them changing over time with the aim of identifying significant changes in their abundance. In population genetics, for example, allele frequencies are monitored over time to detect significant frequency changes that indicate selection pressures. Previous attempts at analysing data from HTS experiments have been limited as they could not simultaneously include data at intermediate "},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1403.4086","kind":"arxiv","version":3},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"aliases":[{"alias_kind":"arxiv","alias_value":"1403.4086","created_at":"2026-05-18T02:42:37.162978+00:00"},{"alias_kind":"arxiv_version","alias_value":"1403.4086v3","created_at":"2026-05-18T02:42:37.162978+00:00"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1403.4086","created_at":"2026-05-18T02:42:37.162978+00:00"},{"alias_kind":"pith_short_12","alias_value":"LTAJAWBGKDBT","created_at":"2026-05-18T12:28:38.356838+00:00"},{"alias_kind":"pith_short_16","alias_value":"LTAJAWBGKDBTFARD","created_at":"2026-05-18T12:28:38.356838+00:00"},{"alias_kind":"pith_short_8","alias_value":"LTAJAWBG","created_at":"2026-05-18T12:28:38.356838+00:00"}],"events":[],"event_summary":{},"paper_claims":[],"inbound_citations":{"count":0,"internal_anchor_count":0,"sample":[]},"formal_canon":{"evidence_count":0,"sample":[],"anchors":[]},"links":{"html":"https://pith.science/pith/LTAJAWBGKDBTFARDTF3DRBLUD7","json":"https://pith.science/pith/LTAJAWBGKDBTFARDTF3DRBLUD7.json","graph_json":"https://pith.science/api/pith-number/LTAJAWBGKDBTFARDTF3DRBLUD7/graph.json","events_json":"https://pith.science/api/pith-number/LTAJAWBGKDBTFARDTF3DRBLUD7/events.json","paper":"https://pith.science/paper/LTAJAWBG"},"agent_actions":{"view_html":"https://pith.science/pith/LTAJAWBGKDBTFARDTF3DRBLUD7","download_json":"https://pith.science/pith/LTAJAWBGKDBTFARDTF3DRBLUD7.json","view_paper":"https://pith.science/paper/LTAJAWBG","resolve_alias":"https://pith.science/api/pith-number/resolve?arxiv=1403.4086&json=true","fetch_graph":"https://pith.science/api/pith-number/LTAJAWBGKDBTFARDTF3DRBLUD7/graph.json","fetch_events":"https://pith.science/api/pith-number/LTAJAWBGKDBTFARDTF3DRBLUD7/events.json","actions":{"anchor_timestamp":"https://pith.science/pith/LTAJAWBGKDBTFARDTF3DRBLUD7/action/timestamp_anchor","attest_storage":"https://pith.science/pith/LTAJAWBGKDBTFARDTF3DRBLUD7/action/storage_attestation","attest_author":"https://pith.science/pith/LTAJAWBGKDBTFARDTF3DRBLUD7/action/author_attestation","sign_citation":"https://pith.science/pith/LTAJAWBGKDBTFARDTF3DRBLUD7/action/citation_signature","submit_replication":"https://pith.science/pith/LTAJAWBGKDBTFARDTF3DRBLUD7/action/replication_record"}},"created_at":"2026-05-18T02:42:37.162978+00:00","updated_at":"2026-05-18T02:42:37.162978+00:00"}