{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2013:ML2YWHUG7II6AAJCR4XXHI6ZZA","short_pith_number":"pith:ML2YWHUG","canonical_record":{"source":{"id":"1301.3077","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.GN","submitted_at":"2013-01-14T17:52:37Z","cross_cats_sorted":[],"title_canon_sha256":"d449a3b55620b6965b1bbf33c4a514c8d3c37d1c1eba378f40ac55f128edc068","abstract_canon_sha256":"d7b42f07b5451c44f6fda3fa349f2c5dc057b81716017fa2d9c97b03b8957c16"},"schema_version":"1.0"},"canonical_sha256":"62f58b1e86fa11e001228f2f73a3d9c80baf161ab0cc8ba3b572b81d9ce6e6e7","source":{"kind":"arxiv","id":"1301.3077","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1301.3077","created_at":"2026-05-18T03:36:27Z"},{"alias_kind":"arxiv_version","alias_value":"1301.3077v1","created_at":"2026-05-18T03:36:27Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1301.3077","created_at":"2026-05-18T03:36:27Z"},{"alias_kind":"pith_short_12","alias_value":"ML2YWHUG7II6","created_at":"2026-05-18T12:27:52Z"},{"alias_kind":"pith_short_16","alias_value":"ML2YWHUG7II6AAJC","created_at":"2026-05-18T12:27:52Z"},{"alias_kind":"pith_short_8","alias_value":"ML2YWHUG","created_at":"2026-05-18T12:27:52Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2013:ML2YWHUG7II6AAJCR4XXHI6ZZA","target":"record","payload":{"canonical_record":{"source":{"id":"1301.3077","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.GN","submitted_at":"2013-01-14T17:52:37Z","cross_cats_sorted":[],"title_canon_sha256":"d449a3b55620b6965b1bbf33c4a514c8d3c37d1c1eba378f40ac55f128edc068","abstract_canon_sha256":"d7b42f07b5451c44f6fda3fa349f2c5dc057b81716017fa2d9c97b03b8957c16"},"schema_version":"1.0"},"canonical_sha256":"62f58b1e86fa11e001228f2f73a3d9c80baf161ab0cc8ba3b572b81d9ce6e6e7","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T03:36:27.527573Z","signature_b64":"lhbqmzS2cwG04AbtYymkKYaiQUbip9FACqcV3BGLv59TKyPiTcOZDJy7D97LX+2UpRF4IY0FFNtMNoytG0iTCQ==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"62f58b1e86fa11e001228f2f73a3d9c80baf161ab0cc8ba3b572b81d9ce6e6e7","last_reissued_at":"2026-05-18T03:36:27.526982Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T03:36:27.526982Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1301.3077","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T03:36:27Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"iMx1SmluqKe4vtNaWPbuOM7zXPzM5tIHrjF14aLp0GSSXfG5m/4gqnmRLS7zg/erMdXqQvdNM0nWu+rvlBDACg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-27T07:40:01.372608Z"},"content_sha256":"cbb29fe3c2be80689b79f8781656170d4e2f906759501a126969e2d1b31204f8","schema_version":"1.0","event_id":"sha256:cbb29fe3c2be80689b79f8781656170d4e2f906759501a126969e2d1b31204f8"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2013:ML2YWHUG7II6AAJCR4XXHI6ZZA","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Kerfuffle: a web tool for multi-species gene colocalization analysis","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"q-bio.GN","authors_text":"Bernard Fendler, Gurinder S. Atwal, Robert Aboukhalil","submitted_at":"2013-01-14T17:52:37Z","abstract_excerpt":"The evolutionary pressures that underlie the large-scale functional organization of the genome are not well understood in eukaryotes. Recent evidence suggests that functionally similar genes may colocalize (cluster) in the eukaryotic genome, suggesting the role of chromatin-level gene regulation in shaping the physical distribution of coordinated genes. However, few of the bioinformatic tools currently available allow for a systematic study of gene colocalization across several, evolutionarily distant species. Kerfuffle is a web tool designed to help discover, visualize, and quantify the physi"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1301.3077","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T03:36:27Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"G3WlkeA80HMDCHiBK4H06rsaCFATybnVgGNlRtGe3iZ32RggM7Qven/o/l7eSeVpJBZfBaNIhqWLNnkVZLgrDw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-27T07:40:01.373272Z"},"content_sha256":"a28e711b700fe6541255d31dde5c3b2a67e06f667249bfc8ae7d0fb8dae31993","schema_version":"1.0","event_id":"sha256:a28e711b700fe6541255d31dde5c3b2a67e06f667249bfc8ae7d0fb8dae31993"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/ML2YWHUG7II6AAJCR4XXHI6ZZA/bundle.json","state_url":"https://pith.science/pith/ML2YWHUG7II6AAJCR4XXHI6ZZA/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/ML2YWHUG7II6AAJCR4XXHI6ZZA/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-05-27T07:40:01Z","links":{"resolver":"https://pith.science/pith/ML2YWHUG7II6AAJCR4XXHI6ZZA","bundle":"https://pith.science/pith/ML2YWHUG7II6AAJCR4XXHI6ZZA/bundle.json","state":"https://pith.science/pith/ML2YWHUG7II6AAJCR4XXHI6ZZA/state.json","well_known_bundle":"https://pith.science/.well-known/pith/ML2YWHUG7II6AAJCR4XXHI6ZZA/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2013:ML2YWHUG7II6AAJCR4XXHI6ZZA","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"d7b42f07b5451c44f6fda3fa349f2c5dc057b81716017fa2d9c97b03b8957c16","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.GN","submitted_at":"2013-01-14T17:52:37Z","title_canon_sha256":"d449a3b55620b6965b1bbf33c4a514c8d3c37d1c1eba378f40ac55f128edc068"},"schema_version":"1.0","source":{"id":"1301.3077","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1301.3077","created_at":"2026-05-18T03:36:27Z"},{"alias_kind":"arxiv_version","alias_value":"1301.3077v1","created_at":"2026-05-18T03:36:27Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1301.3077","created_at":"2026-05-18T03:36:27Z"},{"alias_kind":"pith_short_12","alias_value":"ML2YWHUG7II6","created_at":"2026-05-18T12:27:52Z"},{"alias_kind":"pith_short_16","alias_value":"ML2YWHUG7II6AAJC","created_at":"2026-05-18T12:27:52Z"},{"alias_kind":"pith_short_8","alias_value":"ML2YWHUG","created_at":"2026-05-18T12:27:52Z"}],"graph_snapshots":[{"event_id":"sha256:a28e711b700fe6541255d31dde5c3b2a67e06f667249bfc8ae7d0fb8dae31993","target":"graph","created_at":"2026-05-18T03:36:27Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"The evolutionary pressures that underlie the large-scale functional organization of the genome are not well understood in eukaryotes. Recent evidence suggests that functionally similar genes may colocalize (cluster) in the eukaryotic genome, suggesting the role of chromatin-level gene regulation in shaping the physical distribution of coordinated genes. However, few of the bioinformatic tools currently available allow for a systematic study of gene colocalization across several, evolutionarily distant species. Kerfuffle is a web tool designed to help discover, visualize, and quantify the physi","authors_text":"Bernard Fendler, Gurinder S. Atwal, Robert Aboukhalil","cross_cats":[],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.GN","submitted_at":"2013-01-14T17:52:37Z","title":"Kerfuffle: a web tool for multi-species gene colocalization analysis"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1301.3077","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:cbb29fe3c2be80689b79f8781656170d4e2f906759501a126969e2d1b31204f8","target":"record","created_at":"2026-05-18T03:36:27Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"d7b42f07b5451c44f6fda3fa349f2c5dc057b81716017fa2d9c97b03b8957c16","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.GN","submitted_at":"2013-01-14T17:52:37Z","title_canon_sha256":"d449a3b55620b6965b1bbf33c4a514c8d3c37d1c1eba378f40ac55f128edc068"},"schema_version":"1.0","source":{"id":"1301.3077","kind":"arxiv","version":1}},"canonical_sha256":"62f58b1e86fa11e001228f2f73a3d9c80baf161ab0cc8ba3b572b81d9ce6e6e7","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"62f58b1e86fa11e001228f2f73a3d9c80baf161ab0cc8ba3b572b81d9ce6e6e7","first_computed_at":"2026-05-18T03:36:27.526982Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T03:36:27.526982Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"lhbqmzS2cwG04AbtYymkKYaiQUbip9FACqcV3BGLv59TKyPiTcOZDJy7D97LX+2UpRF4IY0FFNtMNoytG0iTCQ==","signature_status":"signed_v1","signed_at":"2026-05-18T03:36:27.527573Z","signed_message":"canonical_sha256_bytes"},"source_id":"1301.3077","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:cbb29fe3c2be80689b79f8781656170d4e2f906759501a126969e2d1b31204f8","sha256:a28e711b700fe6541255d31dde5c3b2a67e06f667249bfc8ae7d0fb8dae31993"],"state_sha256":"4556f885565d74e9752847da84b2ace10e290d35f02e97dc6dc2598878195bc1"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"CttgI00ei6kFCHndCcqFs2dezHwyxF+X9hmt9h1SVlYNgBGSw54vFI/qQ/lDydIz+S67qnYARrbDvXm4XSSmCQ==","signed_message":"bundle_sha256_bytes","signed_at":"2026-05-27T07:40:01.376896Z","bundle_sha256":"5be03c3adc8794b92ab96527d1cd547dda2abf186e2efd0b0266a85d3fd8e0b0"}}