{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2019:MVEEY7K3IMPUK3TDCPVVVPESWX","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"bd666b2924d878e423ae97d10b7fc32abac9ccc36f6436b11e1487c19039dec7","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.CB","submitted_at":"2019-08-08T00:46:18Z","title_canon_sha256":"24275f9286fefb3a69ebb9356ec6f51d39a9ba82f68124c94c6089a6b9fdd9ba"},"schema_version":"1.0","source":{"id":"1908.02889","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1908.02889","created_at":"2026-07-04T23:52:24Z"},{"alias_kind":"arxiv_version","alias_value":"1908.02889v1","created_at":"2026-07-04T23:52:24Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1908.02889","created_at":"2026-07-04T23:52:24Z"},{"alias_kind":"pith_short_12","alias_value":"MVEEY7K3IMPU","created_at":"2026-07-04T23:52:24Z"},{"alias_kind":"pith_short_16","alias_value":"MVEEY7K3IMPUK3TD","created_at":"2026-07-04T23:52:24Z"},{"alias_kind":"pith_short_8","alias_value":"MVEEY7K3","created_at":"2026-07-04T23:52:24Z"}],"graph_snapshots":[{"event_id":"sha256:71430504401858dcc499e3d76b3acf57c9f535d59d8c11f441124cf0fd3d1962","target":"graph","created_at":"2026-07-04T23:52:24Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/1908.02889/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"Atherosclerosis is characterised by the growth of fatty plaques in the inner (intimal) layer of the artery wall. In mature plaques, vascular smooth muscle cells (SMCs) are recruited from the adjacent medial layer to deposit a cap of fibrous collagen over the fatty plaque core. The fibrous cap isolates the thrombogenic content of the plaque from the bloodstream and prevents the formation of blood clots that cause myocardial infarction or stroke. Despite the important protective role of the cap, the mechanisms that regulate cap formation and maintenance are not well understood. It remains unclea","authors_text":"Charlie Macaskill, Helen M. Byrne, Mary R. Myerscough, Michael G. Watson","cross_cats":[],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.CB","submitted_at":"2019-08-08T00:46:18Z","title":"A Multiphase Model of Growth Factor-Regulated Atherosclerotic Cap Formation"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1908.02889","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:e130184a26704e32d5faf5df4871568ecd590e372688005d4e75d0ef83472ab9","target":"record","created_at":"2026-07-04T23:52:24Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"bd666b2924d878e423ae97d10b7fc32abac9ccc36f6436b11e1487c19039dec7","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.CB","submitted_at":"2019-08-08T00:46:18Z","title_canon_sha256":"24275f9286fefb3a69ebb9356ec6f51d39a9ba82f68124c94c6089a6b9fdd9ba"},"schema_version":"1.0","source":{"id":"1908.02889","kind":"arxiv","version":1}},"canonical_sha256":"65484c7d5b431f456e6313eb5abc92b5dfdd74d683159320a1fbb09462a18da3","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"65484c7d5b431f456e6313eb5abc92b5dfdd74d683159320a1fbb09462a18da3","first_computed_at":"2026-07-04T23:52:24.503338Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-04T23:52:24.503338Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"jbERQPkpAG1YEWx7fuO+6nKekAyvR7//OGKlyIsnajMdvEvnVuWsi3I6FYQdfTB2Pnhg4URgYT6sAxMzava8Bg==","signature_status":"signed_v1","signed_at":"2026-07-04T23:52:24.503714Z","signed_message":"canonical_sha256_bytes"},"source_id":"1908.02889","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:e130184a26704e32d5faf5df4871568ecd590e372688005d4e75d0ef83472ab9","sha256:71430504401858dcc499e3d76b3acf57c9f535d59d8c11f441124cf0fd3d1962"],"state_sha256":"1a34992851b47048d38944d52a267ba4402bffd8dd14dd2d21146834e6299c41"}