{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2018:MWJXZ2LDPEJ76T72PHJYLU47KL","short_pith_number":"pith:MWJXZ2LD","canonical_record":{"source":{"id":"1810.00226","kind":"arxiv","version":3},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cs.IT","submitted_at":"2018-09-29T15:59:43Z","cross_cats_sorted":["math.IT"],"title_canon_sha256":"8370da1dffebbb7ba5261afe19ebfc83d47e9dae6db38358f1088584b6b1ef15","abstract_canon_sha256":"47ace49920309853ac26df3bd0b5d9e46aaaafe927e91ce7a3a17ac0d6a09954"},"schema_version":"1.0"},"canonical_sha256":"65937ce9637913ff4ffa79d385d39f52fff5f9b281f107d57e8a8dd5c78ef2e1","source":{"kind":"arxiv","id":"1810.00226","version":3},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1810.00226","created_at":"2026-07-05T05:10:51Z"},{"alias_kind":"arxiv_version","alias_value":"1810.00226v3","created_at":"2026-07-05T05:10:51Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1810.00226","created_at":"2026-07-05T05:10:51Z"},{"alias_kind":"pith_short_12","alias_value":"MWJXZ2LDPEJ7","created_at":"2026-07-05T05:10:51Z"},{"alias_kind":"pith_short_16","alias_value":"MWJXZ2LDPEJ76T72","created_at":"2026-07-05T05:10:51Z"},{"alias_kind":"pith_short_8","alias_value":"MWJXZ2LD","created_at":"2026-07-05T05:10:51Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2018:MWJXZ2LDPEJ76T72PHJYLU47KL","target":"record","payload":{"canonical_record":{"source":{"id":"1810.00226","kind":"arxiv","version":3},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cs.IT","submitted_at":"2018-09-29T15:59:43Z","cross_cats_sorted":["math.IT"],"title_canon_sha256":"8370da1dffebbb7ba5261afe19ebfc83d47e9dae6db38358f1088584b6b1ef15","abstract_canon_sha256":"47ace49920309853ac26df3bd0b5d9e46aaaafe927e91ce7a3a17ac0d6a09954"},"schema_version":"1.0"},"canonical_sha256":"65937ce9637913ff4ffa79d385d39f52fff5f9b281f107d57e8a8dd5c78ef2e1","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-07-05T05:10:51.102802Z","signature_b64":"MHcvMNLcS00UMASMOlC3YOC8S+fFZ+X+vAsukFhWu4cvoOFTsaoHYTThD/1KvlPWwl7ZU5+cmnfaP+o/wkYTCA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"65937ce9637913ff4ffa79d385d39f52fff5f9b281f107d57e8a8dd5c78ef2e1","last_reissued_at":"2026-07-05T05:10:51.102348Z","signature_status":"signed_v1","first_computed_at":"2026-07-05T05:10:51.102348Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1810.00226","source_version":3,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T05:10:51Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"9gZPe/PKx6GAA+qdE0Dl/sviOLpg9biEBvPvxYVbjDeLBX6T86OExWWzV+M5cVM2KnHuSnef4dUHNHd+IFjICg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-17T19:07:19.425619Z"},"content_sha256":"48c14f16c0fb5a0b6120151f6cf85f13677005b283c1338788d76717b32321a1","schema_version":"1.0","event_id":"sha256:48c14f16c0fb5a0b6120151f6cf85f13677005b283c1338788d76717b32321a1"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2018:MWJXZ2LDPEJ76T72PHJYLU47KL","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Toward single particle reconstruction without particle picking: Breaking the detection limit","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["math.IT"],"primary_cat":"cs.IT","authors_text":"Amit Singer, Eitan Levin, Nicolas Boumal, Tamir Bendory, William Leeb","submitted_at":"2018-09-29T15:59:43Z","abstract_excerpt":"Single-particle cryo-electron microscopy (cryo-EM) has recently joined X-ray crystallography and NMR spectroscopy as a high-resolution structural method to resolve biological macromolecules. In a cryo-EM experiment, the microscope produces images called micrographs. Projections of the molecule of interest are embedded in the micrographs at unknown locations, and under unknown viewing directions. Standard imaging techniques first locate these projections (detection) and then reconstruct the 3-D structure from them. Unfortunately, high noise levels hinder detection. When reliable detection is re"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1810.00226","kind":"arxiv","version":3},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/1810.00226/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T05:10:51Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"UUVOzy/VwyVLLnaNNLrfTvnLGfRiQptFrvl4UfrN3NhFUszNB6gB6HLaPaTNWGvKbc/r2gTIHJ6VLIb1tPCwBQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-17T19:07:19.426538Z"},"content_sha256":"c737bfe1f7395598e6e525cc2664fab0fedd3bde05fee21bc154f1bdb832cb45","schema_version":"1.0","event_id":"sha256:c737bfe1f7395598e6e525cc2664fab0fedd3bde05fee21bc154f1bdb832cb45"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/MWJXZ2LDPEJ76T72PHJYLU47KL/bundle.json","state_url":"https://pith.science/pith/MWJXZ2LDPEJ76T72PHJYLU47KL/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/MWJXZ2LDPEJ76T72PHJYLU47KL/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-08-17T19:07:19Z","links":{"resolver":"https://pith.science/pith/MWJXZ2LDPEJ76T72PHJYLU47KL","bundle":"https://pith.science/pith/MWJXZ2LDPEJ76T72PHJYLU47KL/bundle.json","state":"https://pith.science/pith/MWJXZ2LDPEJ76T72PHJYLU47KL/state.json","well_known_bundle":"https://pith.science/.well-known/pith/MWJXZ2LDPEJ76T72PHJYLU47KL/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2018:MWJXZ2LDPEJ76T72PHJYLU47KL","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"47ace49920309853ac26df3bd0b5d9e46aaaafe927e91ce7a3a17ac0d6a09954","cross_cats_sorted":["math.IT"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cs.IT","submitted_at":"2018-09-29T15:59:43Z","title_canon_sha256":"8370da1dffebbb7ba5261afe19ebfc83d47e9dae6db38358f1088584b6b1ef15"},"schema_version":"1.0","source":{"id":"1810.00226","kind":"arxiv","version":3}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1810.00226","created_at":"2026-07-05T05:10:51Z"},{"alias_kind":"arxiv_version","alias_value":"1810.00226v3","created_at":"2026-07-05T05:10:51Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1810.00226","created_at":"2026-07-05T05:10:51Z"},{"alias_kind":"pith_short_12","alias_value":"MWJXZ2LDPEJ7","created_at":"2026-07-05T05:10:51Z"},{"alias_kind":"pith_short_16","alias_value":"MWJXZ2LDPEJ76T72","created_at":"2026-07-05T05:10:51Z"},{"alias_kind":"pith_short_8","alias_value":"MWJXZ2LD","created_at":"2026-07-05T05:10:51Z"}],"graph_snapshots":[{"event_id":"sha256:c737bfe1f7395598e6e525cc2664fab0fedd3bde05fee21bc154f1bdb832cb45","target":"graph","created_at":"2026-07-05T05:10:51Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/1810.00226/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"Single-particle cryo-electron microscopy (cryo-EM) has recently joined X-ray crystallography and NMR spectroscopy as a high-resolution structural method to resolve biological macromolecules. In a cryo-EM experiment, the microscope produces images called micrographs. Projections of the molecule of interest are embedded in the micrographs at unknown locations, and under unknown viewing directions. Standard imaging techniques first locate these projections (detection) and then reconstruct the 3-D structure from them. Unfortunately, high noise levels hinder detection. When reliable detection is re","authors_text":"Amit Singer, Eitan Levin, Nicolas Boumal, Tamir Bendory, William Leeb","cross_cats":["math.IT"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cs.IT","submitted_at":"2018-09-29T15:59:43Z","title":"Toward single particle reconstruction without particle picking: Breaking the detection limit"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1810.00226","kind":"arxiv","version":3},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:48c14f16c0fb5a0b6120151f6cf85f13677005b283c1338788d76717b32321a1","target":"record","created_at":"2026-07-05T05:10:51Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"47ace49920309853ac26df3bd0b5d9e46aaaafe927e91ce7a3a17ac0d6a09954","cross_cats_sorted":["math.IT"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cs.IT","submitted_at":"2018-09-29T15:59:43Z","title_canon_sha256":"8370da1dffebbb7ba5261afe19ebfc83d47e9dae6db38358f1088584b6b1ef15"},"schema_version":"1.0","source":{"id":"1810.00226","kind":"arxiv","version":3}},"canonical_sha256":"65937ce9637913ff4ffa79d385d39f52fff5f9b281f107d57e8a8dd5c78ef2e1","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"65937ce9637913ff4ffa79d385d39f52fff5f9b281f107d57e8a8dd5c78ef2e1","first_computed_at":"2026-07-05T05:10:51.102348Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-05T05:10:51.102348Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"MHcvMNLcS00UMASMOlC3YOC8S+fFZ+X+vAsukFhWu4cvoOFTsaoHYTThD/1KvlPWwl7ZU5+cmnfaP+o/wkYTCA==","signature_status":"signed_v1","signed_at":"2026-07-05T05:10:51.102802Z","signed_message":"canonical_sha256_bytes"},"source_id":"1810.00226","source_kind":"arxiv","source_version":3}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:48c14f16c0fb5a0b6120151f6cf85f13677005b283c1338788d76717b32321a1","sha256:c737bfe1f7395598e6e525cc2664fab0fedd3bde05fee21bc154f1bdb832cb45"],"state_sha256":"014dbb7a7824af34b53512eb303381b337f72f1503c2bb59b810e8d97ebb8740"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"Vwg3KauUVZ6/rvH27mBeDxey0bQSa3XWpon64A8X4Ara/ieIgJRrcJewUX1szq0lLCZSS24R6d3Sd4/Jv8EhAA==","signed_message":"bundle_sha256_bytes","signed_at":"2026-08-17T19:07:19.461995Z","bundle_sha256":"c3b388fde425ace83459a602cc28c27674fb50dcf65c085130d67def8f793f73"}}