{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2018:MZ5IMN4U7LJF7CDIIDL5D4IF2K","short_pith_number":"pith:MZ5IMN4U","canonical_record":{"source":{"id":"1810.08284","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.PE","submitted_at":"2018-10-18T21:57:42Z","cross_cats_sorted":["physics.soc-ph"],"title_canon_sha256":"df62aef073c5e2a489a794909e6993f0976d9226b3ec99d37a3ed148140e4a90","abstract_canon_sha256":"3c6144364ece4176f2d195de6c9a1f81fd6a67184197bfed70983fc1f8738b11"},"schema_version":"1.0"},"canonical_sha256":"667a863794fad25f886840d7d1f105d285ed27c4cc371d95258c8c874b46d003","source":{"kind":"arxiv","id":"1810.08284","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1810.08284","created_at":"2026-05-18T00:02:44Z"},{"alias_kind":"arxiv_version","alias_value":"1810.08284v1","created_at":"2026-05-18T00:02:44Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1810.08284","created_at":"2026-05-18T00:02:44Z"},{"alias_kind":"pith_short_12","alias_value":"MZ5IMN4U7LJF","created_at":"2026-05-18T12:32:40Z"},{"alias_kind":"pith_short_16","alias_value":"MZ5IMN4U7LJF7CDI","created_at":"2026-05-18T12:32:40Z"},{"alias_kind":"pith_short_8","alias_value":"MZ5IMN4U","created_at":"2026-05-18T12:32:40Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2018:MZ5IMN4U7LJF7CDIIDL5D4IF2K","target":"record","payload":{"canonical_record":{"source":{"id":"1810.08284","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.PE","submitted_at":"2018-10-18T21:57:42Z","cross_cats_sorted":["physics.soc-ph"],"title_canon_sha256":"df62aef073c5e2a489a794909e6993f0976d9226b3ec99d37a3ed148140e4a90","abstract_canon_sha256":"3c6144364ece4176f2d195de6c9a1f81fd6a67184197bfed70983fc1f8738b11"},"schema_version":"1.0"},"canonical_sha256":"667a863794fad25f886840d7d1f105d285ed27c4cc371d95258c8c874b46d003","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T00:02:44.057166Z","signature_b64":"4k6pECVdz8buKyq17HWAOhsiWnf6QJ1bEXKsDUcJuRJ3vFmFy9BJd1H+VHBGKSjP4zJn+8qo1lHzrFCzuUxdAA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"667a863794fad25f886840d7d1f105d285ed27c4cc371d95258c8c874b46d003","last_reissued_at":"2026-05-18T00:02:44.056616Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T00:02:44.056616Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1810.08284","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T00:02:44Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"xk0/wGo8O1vbQZcS7YqOLHhe/39BeBe52GaeY9FSXWy/WSNLk3N+Jw7GZPdAJjEJAVC5v+iQ5xPZQSkDjuwyBA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-07-03T12:18:33.776864Z"},"content_sha256":"d2393c0ac1cbb1e579dc4bd041b82cc3f0db1ded8587f2843d5f58c36b4a49d3","schema_version":"1.0","event_id":"sha256:d2393c0ac1cbb1e579dc4bd041b82cc3f0db1ded8587f2843d5f58c36b4a49d3"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2018:MZ5IMN4U7LJF7CDIIDL5D4IF2K","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Social learning of prescribing behavior can promote population optimum of antibiotic use","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["physics.soc-ph"],"primary_cat":"q-bio.PE","authors_text":"Feng Fu, Xingru Chen","submitted_at":"2018-10-18T21:57:42Z","abstract_excerpt":"The rise and spread of antibiotic resistance causes worsening medical cost and mortality especially for life-threatening bacteria infections, thereby posing a major threat to global health. Prescribing behavior of physicians is one of the important factors impacting the underlying dynamics of resistance evolution. It remains unclear when individual prescribing decisions can lead to the overuse of antibiotics on the population level, and whether population optimum of antibiotic use can be reached through an adaptive social learning process that governs the evolution of prescribing norm. Here we"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1810.08284","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T00:02:44Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"xOL+g3KIvSzb5nSuLS9UluQBiaOM8X4x7NvTT174nCkClu9Y4QMfXiMm8vKn3Th7UBZbwquQSFyTIhKUp0TrAw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-07-03T12:18:33.777199Z"},"content_sha256":"32ec0109bdbc9dde626af4a75e0b5964b7815cfd4b5249d4fdd5b9047bce4b47","schema_version":"1.0","event_id":"sha256:32ec0109bdbc9dde626af4a75e0b5964b7815cfd4b5249d4fdd5b9047bce4b47"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/MZ5IMN4U7LJF7CDIIDL5D4IF2K/bundle.json","state_url":"https://pith.science/pith/MZ5IMN4U7LJF7CDIIDL5D4IF2K/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/MZ5IMN4U7LJF7CDIIDL5D4IF2K/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-07-03T12:18:33Z","links":{"resolver":"https://pith.science/pith/MZ5IMN4U7LJF7CDIIDL5D4IF2K","bundle":"https://pith.science/pith/MZ5IMN4U7LJF7CDIIDL5D4IF2K/bundle.json","state":"https://pith.science/pith/MZ5IMN4U7LJF7CDIIDL5D4IF2K/state.json","well_known_bundle":"https://pith.science/.well-known/pith/MZ5IMN4U7LJF7CDIIDL5D4IF2K/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2018:MZ5IMN4U7LJF7CDIIDL5D4IF2K","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"3c6144364ece4176f2d195de6c9a1f81fd6a67184197bfed70983fc1f8738b11","cross_cats_sorted":["physics.soc-ph"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.PE","submitted_at":"2018-10-18T21:57:42Z","title_canon_sha256":"df62aef073c5e2a489a794909e6993f0976d9226b3ec99d37a3ed148140e4a90"},"schema_version":"1.0","source":{"id":"1810.08284","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1810.08284","created_at":"2026-05-18T00:02:44Z"},{"alias_kind":"arxiv_version","alias_value":"1810.08284v1","created_at":"2026-05-18T00:02:44Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1810.08284","created_at":"2026-05-18T00:02:44Z"},{"alias_kind":"pith_short_12","alias_value":"MZ5IMN4U7LJF","created_at":"2026-05-18T12:32:40Z"},{"alias_kind":"pith_short_16","alias_value":"MZ5IMN4U7LJF7CDI","created_at":"2026-05-18T12:32:40Z"},{"alias_kind":"pith_short_8","alias_value":"MZ5IMN4U","created_at":"2026-05-18T12:32:40Z"}],"graph_snapshots":[{"event_id":"sha256:32ec0109bdbc9dde626af4a75e0b5964b7815cfd4b5249d4fdd5b9047bce4b47","target":"graph","created_at":"2026-05-18T00:02:44Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"The rise and spread of antibiotic resistance causes worsening medical cost and mortality especially for life-threatening bacteria infections, thereby posing a major threat to global health. Prescribing behavior of physicians is one of the important factors impacting the underlying dynamics of resistance evolution. It remains unclear when individual prescribing decisions can lead to the overuse of antibiotics on the population level, and whether population optimum of antibiotic use can be reached through an adaptive social learning process that governs the evolution of prescribing norm. Here we","authors_text":"Feng Fu, Xingru Chen","cross_cats":["physics.soc-ph"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.PE","submitted_at":"2018-10-18T21:57:42Z","title":"Social learning of prescribing behavior can promote population optimum of antibiotic use"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1810.08284","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:d2393c0ac1cbb1e579dc4bd041b82cc3f0db1ded8587f2843d5f58c36b4a49d3","target":"record","created_at":"2026-05-18T00:02:44Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"3c6144364ece4176f2d195de6c9a1f81fd6a67184197bfed70983fc1f8738b11","cross_cats_sorted":["physics.soc-ph"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.PE","submitted_at":"2018-10-18T21:57:42Z","title_canon_sha256":"df62aef073c5e2a489a794909e6993f0976d9226b3ec99d37a3ed148140e4a90"},"schema_version":"1.0","source":{"id":"1810.08284","kind":"arxiv","version":1}},"canonical_sha256":"667a863794fad25f886840d7d1f105d285ed27c4cc371d95258c8c874b46d003","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"667a863794fad25f886840d7d1f105d285ed27c4cc371d95258c8c874b46d003","first_computed_at":"2026-05-18T00:02:44.056616Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T00:02:44.056616Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"4k6pECVdz8buKyq17HWAOhsiWnf6QJ1bEXKsDUcJuRJ3vFmFy9BJd1H+VHBGKSjP4zJn+8qo1lHzrFCzuUxdAA==","signature_status":"signed_v1","signed_at":"2026-05-18T00:02:44.057166Z","signed_message":"canonical_sha256_bytes"},"source_id":"1810.08284","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:d2393c0ac1cbb1e579dc4bd041b82cc3f0db1ded8587f2843d5f58c36b4a49d3","sha256:32ec0109bdbc9dde626af4a75e0b5964b7815cfd4b5249d4fdd5b9047bce4b47"],"state_sha256":"ee0fc5af73bee06bbb33317d7f67871c234eeadf0299b6a06a594942947d2590"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"hjoQIKKewY8cCIXY+dFps5yNQP/ZZHG2K7tpHMK+1FJvuiH0Ohvqz+LEmwAA7QRHENr8sMlXR6aCRd0wBolICw==","signed_message":"bundle_sha256_bytes","signed_at":"2026-07-03T12:18:33.779119Z","bundle_sha256":"abd6e7da45d4808ff12bed3f526652c4d09e309bb032e23d647af739b0270461"}}