{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2021:NDCKULL3LE5UAST6ACW3MG6H7Y","short_pith_number":"pith:NDCKULL3","canonical_record":{"source":{"id":"2103.07520","kind":"arxiv","version":2},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.optics","submitted_at":"2021-03-12T20:50:01Z","cross_cats_sorted":["cond-mat.mes-hall","cond-mat.soft","physics.ins-det"],"title_canon_sha256":"d028caa4d0da24c86b74cf18882e7c17f3a96377a54c8521b35bc6950cfb2eb4","abstract_canon_sha256":"6879d48dec3446153634714c950b9cbfc7dd6627ae8b09d0e7aa588a09ffd394"},"schema_version":"1.0"},"canonical_sha256":"68c4aa2d7b593b404a7e00adb61bc7fe01c665d3ef7105f10901831d888ef8c1","source":{"kind":"arxiv","id":"2103.07520","version":2},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2103.07520","created_at":"2026-07-05T03:12:47Z"},{"alias_kind":"arxiv_version","alias_value":"2103.07520v2","created_at":"2026-07-05T03:12:47Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2103.07520","created_at":"2026-07-05T03:12:47Z"},{"alias_kind":"pith_short_12","alias_value":"NDCKULL3LE5U","created_at":"2026-07-05T03:12:47Z"},{"alias_kind":"pith_short_16","alias_value":"NDCKULL3LE5UAST6","created_at":"2026-07-05T03:12:47Z"},{"alias_kind":"pith_short_8","alias_value":"NDCKULL3","created_at":"2026-07-05T03:12:47Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2021:NDCKULL3LE5UAST6ACW3MG6H7Y","target":"record","payload":{"canonical_record":{"source":{"id":"2103.07520","kind":"arxiv","version":2},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.optics","submitted_at":"2021-03-12T20:50:01Z","cross_cats_sorted":["cond-mat.mes-hall","cond-mat.soft","physics.ins-det"],"title_canon_sha256":"d028caa4d0da24c86b74cf18882e7c17f3a96377a54c8521b35bc6950cfb2eb4","abstract_canon_sha256":"6879d48dec3446153634714c950b9cbfc7dd6627ae8b09d0e7aa588a09ffd394"},"schema_version":"1.0"},"canonical_sha256":"68c4aa2d7b593b404a7e00adb61bc7fe01c665d3ef7105f10901831d888ef8c1","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-07-05T03:12:47.215101Z","signature_b64":"jBV7TCNvGrkxF3SUJYruAYK5xN5LqVGNE+ZLUE4UZMkHKQ06MCpEkFMZmLzsY1LUGJifXMhgrt1bSxHWyN9tCA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"68c4aa2d7b593b404a7e00adb61bc7fe01c665d3ef7105f10901831d888ef8c1","last_reissued_at":"2026-07-05T03:12:47.214511Z","signature_status":"signed_v1","first_computed_at":"2026-07-05T03:12:47.214511Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"2103.07520","source_version":2,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T03:12:47Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"6Ar40/1SCEK2EiSZgCX5p3an9VNksERfLLiIyaYuJKXICBs541VxUbyN6djRDFaHRLnztnq97g3h/CFOFCiFAw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-07-07T04:14:02.445234Z"},"content_sha256":"ce551a7083ad24eed9d466a8450db7e865218cf08a261e5ef421910fbd244ecb","schema_version":"1.0","event_id":"sha256:ce551a7083ad24eed9d466a8450db7e865218cf08a261e5ef421910fbd244ecb"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2021:NDCKULL3LE5UAST6ACW3MG6H7Y","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Comparing transient oligonucleotide hybridization kinetics using DNA-PAINT and optoplasmonic single-molecule sensing on gold nanorods","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["cond-mat.mes-hall","cond-mat.soft","physics.ins-det"],"primary_cat":"physics.optics","authors_text":"Christian Soeller, Frank Vollmer, Hsin-Yu Wu, Janet Anders, Jes\\'us Rubio, Narima Eerqing, Sivaraman Subramanian, Tobias Lutz","submitted_at":"2021-03-12T20:50:01Z","abstract_excerpt":"We report a comparison of two photonic techniques for single-molecule sensing: fluorescence nanoscopy and optoplasmonic sensing. As the test system, oligonucleotides with and without fluorescent labels are transiently hybridized to complementary docking strands attached to gold nanorods. Comparing the measured single-molecule kinetics helps to examine the influence of fluorescent labels as well as factors arising from different sensing geometries. Our results demonstrate that DNA dissociation is not significantly altered by the fluorescent label, while DNA association is affected by geometric "},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2103.07520","kind":"arxiv","version":2},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2103.07520/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T03:12:47Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"MzXkvLaBl7byykW7CCzq4awE1zh1fINkmo2NxJdPgYOdbQ437w+t8Nci3ZsimTyIDqTLQ7eRGryr2dsUMN/vAw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-07-07T04:14:02.445703Z"},"content_sha256":"ca90bdac93df982cf60b1d03f141e34a5c2afa3257d01859841400a3fbfdceee","schema_version":"1.0","event_id":"sha256:ca90bdac93df982cf60b1d03f141e34a5c2afa3257d01859841400a3fbfdceee"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/NDCKULL3LE5UAST6ACW3MG6H7Y/bundle.json","state_url":"https://pith.science/pith/NDCKULL3LE5UAST6ACW3MG6H7Y/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/NDCKULL3LE5UAST6ACW3MG6H7Y/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-07-07T04:14:02Z","links":{"resolver":"https://pith.science/pith/NDCKULL3LE5UAST6ACW3MG6H7Y","bundle":"https://pith.science/pith/NDCKULL3LE5UAST6ACW3MG6H7Y/bundle.json","state":"https://pith.science/pith/NDCKULL3LE5UAST6ACW3MG6H7Y/state.json","well_known_bundle":"https://pith.science/.well-known/pith/NDCKULL3LE5UAST6ACW3MG6H7Y/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2021:NDCKULL3LE5UAST6ACW3MG6H7Y","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"6879d48dec3446153634714c950b9cbfc7dd6627ae8b09d0e7aa588a09ffd394","cross_cats_sorted":["cond-mat.mes-hall","cond-mat.soft","physics.ins-det"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.optics","submitted_at":"2021-03-12T20:50:01Z","title_canon_sha256":"d028caa4d0da24c86b74cf18882e7c17f3a96377a54c8521b35bc6950cfb2eb4"},"schema_version":"1.0","source":{"id":"2103.07520","kind":"arxiv","version":2}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2103.07520","created_at":"2026-07-05T03:12:47Z"},{"alias_kind":"arxiv_version","alias_value":"2103.07520v2","created_at":"2026-07-05T03:12:47Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2103.07520","created_at":"2026-07-05T03:12:47Z"},{"alias_kind":"pith_short_12","alias_value":"NDCKULL3LE5U","created_at":"2026-07-05T03:12:47Z"},{"alias_kind":"pith_short_16","alias_value":"NDCKULL3LE5UAST6","created_at":"2026-07-05T03:12:47Z"},{"alias_kind":"pith_short_8","alias_value":"NDCKULL3","created_at":"2026-07-05T03:12:47Z"}],"graph_snapshots":[{"event_id":"sha256:ca90bdac93df982cf60b1d03f141e34a5c2afa3257d01859841400a3fbfdceee","target":"graph","created_at":"2026-07-05T03:12:47Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2103.07520/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"We report a comparison of two photonic techniques for single-molecule sensing: fluorescence nanoscopy and optoplasmonic sensing. As the test system, oligonucleotides with and without fluorescent labels are transiently hybridized to complementary docking strands attached to gold nanorods. Comparing the measured single-molecule kinetics helps to examine the influence of fluorescent labels as well as factors arising from different sensing geometries. Our results demonstrate that DNA dissociation is not significantly altered by the fluorescent label, while DNA association is affected by geometric ","authors_text":"Christian Soeller, Frank Vollmer, Hsin-Yu Wu, Janet Anders, Jes\\'us Rubio, Narima Eerqing, Sivaraman Subramanian, Tobias Lutz","cross_cats":["cond-mat.mes-hall","cond-mat.soft","physics.ins-det"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.optics","submitted_at":"2021-03-12T20:50:01Z","title":"Comparing transient oligonucleotide hybridization kinetics using DNA-PAINT and optoplasmonic single-molecule sensing on gold nanorods"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2103.07520","kind":"arxiv","version":2},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:ce551a7083ad24eed9d466a8450db7e865218cf08a261e5ef421910fbd244ecb","target":"record","created_at":"2026-07-05T03:12:47Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"6879d48dec3446153634714c950b9cbfc7dd6627ae8b09d0e7aa588a09ffd394","cross_cats_sorted":["cond-mat.mes-hall","cond-mat.soft","physics.ins-det"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.optics","submitted_at":"2021-03-12T20:50:01Z","title_canon_sha256":"d028caa4d0da24c86b74cf18882e7c17f3a96377a54c8521b35bc6950cfb2eb4"},"schema_version":"1.0","source":{"id":"2103.07520","kind":"arxiv","version":2}},"canonical_sha256":"68c4aa2d7b593b404a7e00adb61bc7fe01c665d3ef7105f10901831d888ef8c1","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"68c4aa2d7b593b404a7e00adb61bc7fe01c665d3ef7105f10901831d888ef8c1","first_computed_at":"2026-07-05T03:12:47.214511Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-05T03:12:47.214511Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"jBV7TCNvGrkxF3SUJYruAYK5xN5LqVGNE+ZLUE4UZMkHKQ06MCpEkFMZmLzsY1LUGJifXMhgrt1bSxHWyN9tCA==","signature_status":"signed_v1","signed_at":"2026-07-05T03:12:47.215101Z","signed_message":"canonical_sha256_bytes"},"source_id":"2103.07520","source_kind":"arxiv","source_version":2}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:ce551a7083ad24eed9d466a8450db7e865218cf08a261e5ef421910fbd244ecb","sha256:ca90bdac93df982cf60b1d03f141e34a5c2afa3257d01859841400a3fbfdceee"],"state_sha256":"3857032e8efc1ddeab04c76b79c572b1812e61b7e3e4c0724efe7af1b5bce5ab"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"Bj2o7QTJte+i7I6L0IwaTkU0tSUq8FIV2oK6yy8BLfm8ccEiK9saUHOxPuDCDPS7helcj+IBr0F2c/0aiBUbAg==","signed_message":"bundle_sha256_bytes","signed_at":"2026-07-07T04:14:02.447780Z","bundle_sha256":"4d55d2be61364264cb319c338ee5bb295dc18d0749d0d5ff4bb690fb8975a732"}}