{"record_type":"pith_number_record","schema_url":"https://pith.science/schemas/pith-number/v1.json","pith_number":"pith:2003:NJXJIVTMOKGYACA23K6UCWO3XX","short_pith_number":"pith:NJXJIVTM","schema_version":"1.0","canonical_sha256":"6a6e94566c728d80081adabd4159dbbde67d2d3b3f55e6cb7ab5923a336b522f","source":{"kind":"arxiv","id":"cond-mat/0307557","version":1},"attestation_state":"computed","paper":{"title":"Far Infrared Sensing Of The Oxidation State Of Heme Proteins","license":"","headline":"","cross_cats":["cond-mat.mtrl-sci","q-bio"],"primary_cat":"cond-mat.soft","authors_text":"A. G. Markelz, J. Cerne, J.-Y. Chen","submitted_at":"2003-07-23T04:22:24Z","abstract_excerpt":"We propose a biosensor based on the change of terahertz (THz) dielectric response when a biotarget binds to a probe. The feasibility of this biosensor is examined by studying the change of THz transmission for thin films of heme proteins myoglobin (Mb) and cytochrome C (CytC) as a function oxygen binding. We measure a strong increase in both the index and absorbance with oxygen binding for both Mb and CytC. The measured changes occur for both dried and samples hydrated at 80% r.h. suggesting that using terahertz time domain spectroscopy (TTDS) to monitor the transmitted terahertz pulse through"},"verification_status":{"content_addressed":true,"pith_receipt":true,"author_attested":false,"weak_author_claims":0,"strong_author_claims":0,"externally_anchored":false,"storage_verified":false,"citation_signatures":0,"replication_records":0,"graph_snapshot":true,"references_resolved":false,"formal_links_present":false},"canonical_record":{"source":{"id":"cond-mat/0307557","kind":"arxiv","version":1},"metadata":{"license":"","primary_cat":"cond-mat.soft","submitted_at":"2003-07-23T04:22:24Z","cross_cats_sorted":["cond-mat.mtrl-sci","q-bio"],"title_canon_sha256":"efd5d0e2a5f117ef549c4d546bf6b0d9102f8d5da002e686d373e3b9f5ee7337","abstract_canon_sha256":"48106c0c9a38ac421776d72d6bda2c5b5512f01c46e1253c4387bad06f55c952"},"schema_version":"1.0"},"receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-07-04T14:20:15.765596Z","signature_b64":"0XX7CPN8Peh1FzvlvF4G1ExnP52dTYmVYYsW+Fp3K0ZX3Q7tKIXf2v4L6OEqd+/O1XNy2ss44bamqtIkv9qtCA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"6a6e94566c728d80081adabd4159dbbde67d2d3b3f55e6cb7ab5923a336b522f","last_reissued_at":"2026-07-04T14:20:15.764168Z","signature_status":"signed_v1","first_computed_at":"2026-07-04T14:20:15.764168Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"graph_snapshot":{"paper":{"title":"Far Infrared Sensing Of The Oxidation State Of Heme Proteins","license":"","headline":"","cross_cats":["cond-mat.mtrl-sci","q-bio"],"primary_cat":"cond-mat.soft","authors_text":"A. G. Markelz, J. Cerne, J.-Y. Chen","submitted_at":"2003-07-23T04:22:24Z","abstract_excerpt":"We propose a biosensor based on the change of terahertz (THz) dielectric response when a biotarget binds to a probe. The feasibility of this biosensor is examined by studying the change of THz transmission for thin films of heme proteins myoglobin (Mb) and cytochrome C (CytC) as a function oxygen binding. We measure a strong increase in both the index and absorbance with oxygen binding for both Mb and CytC. The measured changes occur for both dried and samples hydrated at 80% r.h. suggesting that using terahertz time domain spectroscopy (TTDS) to monitor the transmitted terahertz pulse through"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"cond-mat/0307557","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/cond-mat/0307557/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"aliases":[{"alias_kind":"arxiv","alias_value":"cond-mat/0307557","created_at":"2026-07-04T14:20:15.765213+00:00"},{"alias_kind":"arxiv_version","alias_value":"cond-mat/0307557v1","created_at":"2026-07-04T14:20:15.765213+00:00"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.cond-mat/0307557","created_at":"2026-07-04T14:20:15.765213+00:00"},{"alias_kind":"pith_short_12","alias_value":"NJXJIVTMOKGY","created_at":"2026-07-04T14:20:15.765213+00:00"},{"alias_kind":"pith_short_16","alias_value":"NJXJIVTMOKGYACA2","created_at":"2026-07-04T14:20:15.765213+00:00"},{"alias_kind":"pith_short_8","alias_value":"NJXJIVTM","created_at":"2026-07-04T14:20:15.765213+00:00"}],"events":[],"event_summary":{},"paper_claims":[],"inbound_citations":{"count":0,"internal_anchor_count":0,"sample":[]},"formal_canon":{"evidence_count":0,"sample":[],"anchors":[]},"links":{"html":"https://pith.science/pith/NJXJIVTMOKGYACA23K6UCWO3XX","json":"https://pith.science/pith/NJXJIVTMOKGYACA23K6UCWO3XX.json","graph_json":"https://pith.science/api/pith-number/NJXJIVTMOKGYACA23K6UCWO3XX/graph.json","events_json":"https://pith.science/api/pith-number/NJXJIVTMOKGYACA23K6UCWO3XX/events.json","paper":"https://pith.science/paper/NJXJIVTM"},"agent_actions":{"view_html":"https://pith.science/pith/NJXJIVTMOKGYACA23K6UCWO3XX","download_json":"https://pith.science/pith/NJXJIVTMOKGYACA23K6UCWO3XX.json","view_paper":"https://pith.science/paper/NJXJIVTM","resolve_alias":"https://pith.science/api/pith-number/resolve?arxiv=cond-mat/0307557&json=true","fetch_graph":"https://pith.science/api/pith-number/NJXJIVTMOKGYACA23K6UCWO3XX/graph.json","fetch_events":"https://pith.science/api/pith-number/NJXJIVTMOKGYACA23K6UCWO3XX/events.json","actions":{"anchor_timestamp":"https://pith.science/pith/NJXJIVTMOKGYACA23K6UCWO3XX/action/timestamp_anchor","attest_storage":"https://pith.science/pith/NJXJIVTMOKGYACA23K6UCWO3XX/action/storage_attestation","attest_author":"https://pith.science/pith/NJXJIVTMOKGYACA23K6UCWO3XX/action/author_attestation","sign_citation":"https://pith.science/pith/NJXJIVTMOKGYACA23K6UCWO3XX/action/citation_signature","submit_replication":"https://pith.science/pith/NJXJIVTMOKGYACA23K6UCWO3XX/action/replication_record"}},"created_at":"2026-07-04T14:20:15.765213+00:00","updated_at":"2026-07-04T14:20:15.765213+00:00"}