{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2015:NKMHSYCCTCQX2IBH7TKKO4JBO4","short_pith_number":"pith:NKMHSYCC","canonical_record":{"source":{"id":"1508.05562","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2015-08-23T03:14:42Z","cross_cats_sorted":["physics.chem-ph"],"title_canon_sha256":"1b1d85ab7368674d37cbd7e10d00760faeb13ac277373eaeb7369035b7ed9fa3","abstract_canon_sha256":"03ad4f3edbe9d688dcd7c9992e55cc8fea4b66694d5544376191b0d94f2c20a0"},"schema_version":"1.0"},"canonical_sha256":"6a9879604298a17d2027fcd4a771217706a02d50263283fd0486067289947e76","source":{"kind":"arxiv","id":"1508.05562","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1508.05562","created_at":"2026-05-18T01:34:52Z"},{"alias_kind":"arxiv_version","alias_value":"1508.05562v1","created_at":"2026-05-18T01:34:52Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1508.05562","created_at":"2026-05-18T01:34:52Z"},{"alias_kind":"pith_short_12","alias_value":"NKMHSYCCTCQX","created_at":"2026-05-18T12:29:32Z"},{"alias_kind":"pith_short_16","alias_value":"NKMHSYCCTCQX2IBH","created_at":"2026-05-18T12:29:32Z"},{"alias_kind":"pith_short_8","alias_value":"NKMHSYCC","created_at":"2026-05-18T12:29:32Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2015:NKMHSYCCTCQX2IBH7TKKO4JBO4","target":"record","payload":{"canonical_record":{"source":{"id":"1508.05562","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2015-08-23T03:14:42Z","cross_cats_sorted":["physics.chem-ph"],"title_canon_sha256":"1b1d85ab7368674d37cbd7e10d00760faeb13ac277373eaeb7369035b7ed9fa3","abstract_canon_sha256":"03ad4f3edbe9d688dcd7c9992e55cc8fea4b66694d5544376191b0d94f2c20a0"},"schema_version":"1.0"},"canonical_sha256":"6a9879604298a17d2027fcd4a771217706a02d50263283fd0486067289947e76","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T01:34:52.194351Z","signature_b64":"WNvrm5+28OcTNxNZFc5MgWTbntoqOKGKdaI0FlRLL/P+gW94D0GTzt/Nnx2u4JtxN8IrzoJTi5GNwhMghUeVBA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"6a9879604298a17d2027fcd4a771217706a02d50263283fd0486067289947e76","last_reissued_at":"2026-05-18T01:34:52.193801Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T01:34:52.193801Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1508.05562","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T01:34:52Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"vwhMkzwTlncnf3IDt1UZM5Hc5RGeoDG9+96BQbYyRUsub1Y999w1ed3n6LE1dCSLws6KqUaz0vk3NvDd5vESBQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-27T12:58:48.862806Z"},"content_sha256":"96b603226c5866c9d6fa42621decff16124d4df35bf2a298fb22004650bf9f7f","schema_version":"1.0","event_id":"sha256:96b603226c5866c9d6fa42621decff16124d4df35bf2a298fb22004650bf9f7f"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2015:NKMHSYCCTCQX2IBH7TKKO4JBO4","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Role of hydration and intramolecular interactions in the helix-coil transition and helix-helix assembly in a deca-alanine peptide","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["physics.chem-ph"],"primary_cat":"physics.bio-ph","authors_text":"B. M. Pettitt, D. Asthagiri, Dheeraj S. Tomar, Valery Weber","submitted_at":"2015-08-23T03:14:42Z","abstract_excerpt":"For a model deca-alanine peptide the cavity (ideal hydrophobic) contribution to hydration favors the helix state in the coil-to-helix transition and the paired helix bundle in the assembly of two helices. The energetic contributions of attractive protein-solvent interactions are separated into a short-range part arising from interactions with solvent in the first hydration shell and the remaining long-range part. In the helix-coil transition, short-range attractive protein-solvent interactions outweigh hydrophobic hydration and favor the unfolded coil states. Analysis of enthalpic effects show"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1508.05562","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T01:34:52Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"1CbRLX8Nov/MV0ipQHG9E7Pa9A2lExOJHFaFbsCY4/kwVxxDYdiAKHZ4il5u5/odXnUkcb7ityYB/WZh+s/pAg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-27T12:58:48.863430Z"},"content_sha256":"94661209ca36b35248eed60629e559610acbbbfd7c94a3b8646e0431311ff302","schema_version":"1.0","event_id":"sha256:94661209ca36b35248eed60629e559610acbbbfd7c94a3b8646e0431311ff302"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/NKMHSYCCTCQX2IBH7TKKO4JBO4/bundle.json","state_url":"https://pith.science/pith/NKMHSYCCTCQX2IBH7TKKO4JBO4/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/NKMHSYCCTCQX2IBH7TKKO4JBO4/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-05-27T12:58:48Z","links":{"resolver":"https://pith.science/pith/NKMHSYCCTCQX2IBH7TKKO4JBO4","bundle":"https://pith.science/pith/NKMHSYCCTCQX2IBH7TKKO4JBO4/bundle.json","state":"https://pith.science/pith/NKMHSYCCTCQX2IBH7TKKO4JBO4/state.json","well_known_bundle":"https://pith.science/.well-known/pith/NKMHSYCCTCQX2IBH7TKKO4JBO4/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2015:NKMHSYCCTCQX2IBH7TKKO4JBO4","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"03ad4f3edbe9d688dcd7c9992e55cc8fea4b66694d5544376191b0d94f2c20a0","cross_cats_sorted":["physics.chem-ph"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2015-08-23T03:14:42Z","title_canon_sha256":"1b1d85ab7368674d37cbd7e10d00760faeb13ac277373eaeb7369035b7ed9fa3"},"schema_version":"1.0","source":{"id":"1508.05562","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1508.05562","created_at":"2026-05-18T01:34:52Z"},{"alias_kind":"arxiv_version","alias_value":"1508.05562v1","created_at":"2026-05-18T01:34:52Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1508.05562","created_at":"2026-05-18T01:34:52Z"},{"alias_kind":"pith_short_12","alias_value":"NKMHSYCCTCQX","created_at":"2026-05-18T12:29:32Z"},{"alias_kind":"pith_short_16","alias_value":"NKMHSYCCTCQX2IBH","created_at":"2026-05-18T12:29:32Z"},{"alias_kind":"pith_short_8","alias_value":"NKMHSYCC","created_at":"2026-05-18T12:29:32Z"}],"graph_snapshots":[{"event_id":"sha256:94661209ca36b35248eed60629e559610acbbbfd7c94a3b8646e0431311ff302","target":"graph","created_at":"2026-05-18T01:34:52Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"For a model deca-alanine peptide the cavity (ideal hydrophobic) contribution to hydration favors the helix state in the coil-to-helix transition and the paired helix bundle in the assembly of two helices. The energetic contributions of attractive protein-solvent interactions are separated into a short-range part arising from interactions with solvent in the first hydration shell and the remaining long-range part. In the helix-coil transition, short-range attractive protein-solvent interactions outweigh hydrophobic hydration and favor the unfolded coil states. Analysis of enthalpic effects show","authors_text":"B. M. Pettitt, D. Asthagiri, Dheeraj S. Tomar, Valery Weber","cross_cats":["physics.chem-ph"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2015-08-23T03:14:42Z","title":"Role of hydration and intramolecular interactions in the helix-coil transition and helix-helix assembly in a deca-alanine peptide"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1508.05562","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:96b603226c5866c9d6fa42621decff16124d4df35bf2a298fb22004650bf9f7f","target":"record","created_at":"2026-05-18T01:34:52Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"03ad4f3edbe9d688dcd7c9992e55cc8fea4b66694d5544376191b0d94f2c20a0","cross_cats_sorted":["physics.chem-ph"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2015-08-23T03:14:42Z","title_canon_sha256":"1b1d85ab7368674d37cbd7e10d00760faeb13ac277373eaeb7369035b7ed9fa3"},"schema_version":"1.0","source":{"id":"1508.05562","kind":"arxiv","version":1}},"canonical_sha256":"6a9879604298a17d2027fcd4a771217706a02d50263283fd0486067289947e76","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"6a9879604298a17d2027fcd4a771217706a02d50263283fd0486067289947e76","first_computed_at":"2026-05-18T01:34:52.193801Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T01:34:52.193801Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"WNvrm5+28OcTNxNZFc5MgWTbntoqOKGKdaI0FlRLL/P+gW94D0GTzt/Nnx2u4JtxN8IrzoJTi5GNwhMghUeVBA==","signature_status":"signed_v1","signed_at":"2026-05-18T01:34:52.194351Z","signed_message":"canonical_sha256_bytes"},"source_id":"1508.05562","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:96b603226c5866c9d6fa42621decff16124d4df35bf2a298fb22004650bf9f7f","sha256:94661209ca36b35248eed60629e559610acbbbfd7c94a3b8646e0431311ff302"],"state_sha256":"ba892c9c566577963a2f4921daed2b3fd934633285eefd6b37cb5a7cfc0dc809"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"NtdNzVaeEOZQMM53aZxPSOiz+aU4wiH733LkxRHOgaKvE+a+P15lGVB3ZUy9JnEE/HI98eI0zKx/4mXFB1tEDQ==","signed_message":"bundle_sha256_bytes","signed_at":"2026-05-27T12:58:48.866923Z","bundle_sha256":"6fcb5e89b711c6b69788549b6190e02a5a9bb6f8fab24eb2386c43924edff4f5"}}