{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2019:NQH2CNGGJOPAUKS2BFAIEOO5WE","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"3c845c15fbcca277a93cd869c2b4d03c82f9053b18fdcc79140394c67467d2f1","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2019-04-28T17:47:13Z","title_canon_sha256":"133edc14218beb05317ef9a1015e1312c45d01098e7beb55f93a027b9bb47543"},"schema_version":"1.0","source":{"id":"1904.12353","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1904.12353","created_at":"2026-05-17T23:47:35Z"},{"alias_kind":"arxiv_version","alias_value":"1904.12353v1","created_at":"2026-05-17T23:47:35Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1904.12353","created_at":"2026-05-17T23:47:35Z"},{"alias_kind":"pith_short_12","alias_value":"NQH2CNGGJOPA","created_at":"2026-05-18T12:33:24Z"},{"alias_kind":"pith_short_16","alias_value":"NQH2CNGGJOPAUKS2","created_at":"2026-05-18T12:33:24Z"},{"alias_kind":"pith_short_8","alias_value":"NQH2CNGG","created_at":"2026-05-18T12:33:24Z"}],"graph_snapshots":[{"event_id":"sha256:aca99b956d2d7ee047179e3bf4db6ae3e804f7888bf5f065a2d99533be3b80bd","target":"graph","created_at":"2026-05-17T23:47:35Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"Identifying groups of similar objects using clustering approaches is one of the most frequently employed first steps in exploratory biomedical data analysis. Many clustering methods have been developed that pursue different strategies to identify the optimal clustering for a data set.\n  We previously published TiCoNE, an interactive clustering approach coupled with de-novo network enrichment of identified clusters. However, in this first version time-series and network analysis remained two separate steps in that only time-series data was clustered, and identified clusters mapped to and enrich","authors_text":"Christian Wiwie, Jan Baumbach, Richard R\\\"ottger","cross_cats":[],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2019-04-28T17:47:13Z","title":"TiCoNE 2: A Composite Clustering Model for Robust Cluster Analyses on Noisy Data"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1904.12353","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:253e505e085fa69e3f1ada7b898916b11139b0a3cbecc3a09f135a4f71cc4588","target":"record","created_at":"2026-05-17T23:47:35Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"3c845c15fbcca277a93cd869c2b4d03c82f9053b18fdcc79140394c67467d2f1","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2019-04-28T17:47:13Z","title_canon_sha256":"133edc14218beb05317ef9a1015e1312c45d01098e7beb55f93a027b9bb47543"},"schema_version":"1.0","source":{"id":"1904.12353","kind":"arxiv","version":1}},"canonical_sha256":"6c0fa134c64b9e0a2a5a09408239ddb130aee2042827e16e5f24b63264a42de6","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"6c0fa134c64b9e0a2a5a09408239ddb130aee2042827e16e5f24b63264a42de6","first_computed_at":"2026-05-17T23:47:35.374825Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-17T23:47:35.374825Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"3WzkW3VxJDbRoz6dTVFYSrX3eRDhgx3NZsgMCQ7D3F+UQ1UZnFsRpyBfx8+zk4jGeVZ+Mw1dm3B8CTV7ZLYSAQ==","signature_status":"signed_v1","signed_at":"2026-05-17T23:47:35.375430Z","signed_message":"canonical_sha256_bytes"},"source_id":"1904.12353","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:253e505e085fa69e3f1ada7b898916b11139b0a3cbecc3a09f135a4f71cc4588","sha256:aca99b956d2d7ee047179e3bf4db6ae3e804f7888bf5f065a2d99533be3b80bd"],"state_sha256":"ccdf234f8c86357a86950006f58c186073462ee9b6b100b327ccf71b5ce6d3bc"}