{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2016:NRF3HOMRHUYPOYUPIJQYB32JYY","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"509191af85bbc35a7eaeba7cc7973cea476ece9d2c00141cb336afe864a07cd0","cross_cats_sorted":["cond-mat.soft","physics.bio-ph"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.BM","submitted_at":"2016-11-02T23:08:09Z","title_canon_sha256":"44c9ad059ca1752eb2eb275469219b5ced31fbd0c5ba0608ba227636ec0ce2b9"},"schema_version":"1.0","source":{"id":"1611.00836","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1611.00836","created_at":"2026-05-18T01:00:18Z"},{"alias_kind":"arxiv_version","alias_value":"1611.00836v1","created_at":"2026-05-18T01:00:18Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1611.00836","created_at":"2026-05-18T01:00:18Z"},{"alias_kind":"pith_short_12","alias_value":"NRF3HOMRHUYP","created_at":"2026-05-18T12:30:36Z"},{"alias_kind":"pith_short_16","alias_value":"NRF3HOMRHUYPOYUP","created_at":"2026-05-18T12:30:36Z"},{"alias_kind":"pith_short_8","alias_value":"NRF3HOMR","created_at":"2026-05-18T12:30:36Z"}],"graph_snapshots":[{"event_id":"sha256:76a0b594305c2732ef690981ebcc197408f0592c7efbfda260a4430ec81f6b9b","target":"graph","created_at":"2026-05-18T01:00:18Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"Hydrophobic thickness mismatch between integral membrane proteins and the surrounding lipid bilayer can produce lipid bilayer thickness deformations. Experiment and theory have shown that protein-induced lipid bilayer thickness deformations can yield energetically favorable bilayer-mediated interactions between integral membrane proteins, and large-scale organization of integral membrane proteins into protein clusters in cell membranes. Within the continuum elasticity theory of membranes, the energy cost of protein-induced bilayer thickness deformations can be captured by considering compressi","authors_text":"Christoph A. Haselwandter, Osman Kahraman, Peter D. Koch, William S. Klug","cross_cats":["cond-mat.soft","physics.bio-ph"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.BM","submitted_at":"2016-11-02T23:08:09Z","title":"Bilayer-thickness-mediated interactions between integral membrane proteins"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1611.00836","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:14b6c043deb4630505aea26dc8191c22201c4dcf60686961bae8b5941bfa8201","target":"record","created_at":"2026-05-18T01:00:18Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"509191af85bbc35a7eaeba7cc7973cea476ece9d2c00141cb336afe864a07cd0","cross_cats_sorted":["cond-mat.soft","physics.bio-ph"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.BM","submitted_at":"2016-11-02T23:08:09Z","title_canon_sha256":"44c9ad059ca1752eb2eb275469219b5ced31fbd0c5ba0608ba227636ec0ce2b9"},"schema_version":"1.0","source":{"id":"1611.00836","kind":"arxiv","version":1}},"canonical_sha256":"6c4bb3b9913d30f7628f426180ef49c6129b6aabd39ee30b568df4ba232fbebb","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"6c4bb3b9913d30f7628f426180ef49c6129b6aabd39ee30b568df4ba232fbebb","first_computed_at":"2026-05-18T01:00:18.575623Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T01:00:18.575623Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"CNhLv369cJcW77Oon4ljy2I1QH2OdvKM8TZoy3YrGaKEo7U6zTBmTvRY1antiqpz2JnOjawpZs10Q1Q3oAZnDw==","signature_status":"signed_v1","signed_at":"2026-05-18T01:00:18.576269Z","signed_message":"canonical_sha256_bytes"},"source_id":"1611.00836","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:14b6c043deb4630505aea26dc8191c22201c4dcf60686961bae8b5941bfa8201","sha256:76a0b594305c2732ef690981ebcc197408f0592c7efbfda260a4430ec81f6b9b"],"state_sha256":"8df3e7d7eb66e11a7ea0686bd68b93ca5be56902ec494a3ceeb8487892343331"}