{"record_type":"pith_number_record","schema_url":"https://pith.science/schemas/pith-number/v1.json","pith_number":"pith:2013:NUSVVWUERJ6BCZUCBYXP2BQGKL","short_pith_number":"pith:NUSVVWUE","schema_version":"1.0","canonical_sha256":"6d255ada848a7c1166820e2efd060652eda478446886c52f6afb73c7fb16bf59","source":{"kind":"arxiv","id":"1312.5582","version":2},"attestation_state":"computed","paper":{"title":"Tumour Control Probability in Cancer Stem Cells Hypothesis","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["q-bio.TO"],"primary_cat":"q-bio.QM","authors_text":"A. Dhawan, M. Kohandel, R. P. Hill, S. Sivaloganathan","submitted_at":"2013-12-19T15:24:21Z","abstract_excerpt":"The tumour control probability (TCP) is a formalism derived to compare various treatment regimens of radiation therapy, defined as the probability that given a prescribed dose of radiation, a tumour has been eradicated or controlled. In the traditional view of cancer, all cells share the ability to divide without limit and thus have the potential to generate a malignant tumour. However, an emerging notion is that only a sub-population of cells, the so-called cancer stem cells (CSCs), are responsible for the initiation and maintenance of the tumour. A key implication of the CSC hypothesis is th"},"verification_status":{"content_addressed":true,"pith_receipt":true,"author_attested":false,"weak_author_claims":0,"strong_author_claims":0,"externally_anchored":false,"storage_verified":false,"citation_signatures":0,"replication_records":0,"graph_snapshot":true,"references_resolved":false,"formal_links_present":false},"canonical_record":{"source":{"id":"1312.5582","kind":"arxiv","version":2},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2013-12-19T15:24:21Z","cross_cats_sorted":["q-bio.TO"],"title_canon_sha256":"2b8e513d4582560fdd1a47c75893bdcb05e25d94258e2b561017d0b8c936aae8","abstract_canon_sha256":"647a88cb30112204d70cb6f98609e00916f969aecea93e288247ae360beefc2c"},"schema_version":"1.0"},"receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T01:45:43.956459Z","signature_b64":"S254TPbKC2VYYIblbtBpMTmWwGFSiNgXHioygP2wEzyYZ0xA1UexzgmdUPUF/tcsY21ZzwohTQw+xddmmDHlBg==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"6d255ada848a7c1166820e2efd060652eda478446886c52f6afb73c7fb16bf59","last_reissued_at":"2026-05-18T01:45:43.955744Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T01:45:43.955744Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"graph_snapshot":{"paper":{"title":"Tumour Control Probability in Cancer Stem Cells Hypothesis","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["q-bio.TO"],"primary_cat":"q-bio.QM","authors_text":"A. Dhawan, M. Kohandel, R. P. Hill, S. Sivaloganathan","submitted_at":"2013-12-19T15:24:21Z","abstract_excerpt":"The tumour control probability (TCP) is a formalism derived to compare various treatment regimens of radiation therapy, defined as the probability that given a prescribed dose of radiation, a tumour has been eradicated or controlled. In the traditional view of cancer, all cells share the ability to divide without limit and thus have the potential to generate a malignant tumour. However, an emerging notion is that only a sub-population of cells, the so-called cancer stem cells (CSCs), are responsible for the initiation and maintenance of the tumour. A key implication of the CSC hypothesis is th"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1312.5582","kind":"arxiv","version":2},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"aliases":[{"alias_kind":"arxiv","alias_value":"1312.5582","created_at":"2026-05-18T01:45:43.955859+00:00"},{"alias_kind":"arxiv_version","alias_value":"1312.5582v2","created_at":"2026-05-18T01:45:43.955859+00:00"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1312.5582","created_at":"2026-05-18T01:45:43.955859+00:00"},{"alias_kind":"pith_short_12","alias_value":"NUSVVWUERJ6B","created_at":"2026-05-18T12:27:52.871228+00:00"},{"alias_kind":"pith_short_16","alias_value":"NUSVVWUERJ6BCZUC","created_at":"2026-05-18T12:27:52.871228+00:00"},{"alias_kind":"pith_short_8","alias_value":"NUSVVWUE","created_at":"2026-05-18T12:27:52.871228+00:00"}],"events":[],"event_summary":{},"paper_claims":[],"inbound_citations":{"count":0,"internal_anchor_count":0,"sample":[]},"formal_canon":{"evidence_count":0,"sample":[],"anchors":[]},"links":{"html":"https://pith.science/pith/NUSVVWUERJ6BCZUCBYXP2BQGKL","json":"https://pith.science/pith/NUSVVWUERJ6BCZUCBYXP2BQGKL.json","graph_json":"https://pith.science/api/pith-number/NUSVVWUERJ6BCZUCBYXP2BQGKL/graph.json","events_json":"https://pith.science/api/pith-number/NUSVVWUERJ6BCZUCBYXP2BQGKL/events.json","paper":"https://pith.science/paper/NUSVVWUE"},"agent_actions":{"view_html":"https://pith.science/pith/NUSVVWUERJ6BCZUCBYXP2BQGKL","download_json":"https://pith.science/pith/NUSVVWUERJ6BCZUCBYXP2BQGKL.json","view_paper":"https://pith.science/paper/NUSVVWUE","resolve_alias":"https://pith.science/api/pith-number/resolve?arxiv=1312.5582&json=true","fetch_graph":"https://pith.science/api/pith-number/NUSVVWUERJ6BCZUCBYXP2BQGKL/graph.json","fetch_events":"https://pith.science/api/pith-number/NUSVVWUERJ6BCZUCBYXP2BQGKL/events.json","actions":{"anchor_timestamp":"https://pith.science/pith/NUSVVWUERJ6BCZUCBYXP2BQGKL/action/timestamp_anchor","attest_storage":"https://pith.science/pith/NUSVVWUERJ6BCZUCBYXP2BQGKL/action/storage_attestation","attest_author":"https://pith.science/pith/NUSVVWUERJ6BCZUCBYXP2BQGKL/action/author_attestation","sign_citation":"https://pith.science/pith/NUSVVWUERJ6BCZUCBYXP2BQGKL/action/citation_signature","submit_replication":"https://pith.science/pith/NUSVVWUERJ6BCZUCBYXP2BQGKL/action/replication_record"}},"created_at":"2026-05-18T01:45:43.955859+00:00","updated_at":"2026-05-18T01:45:43.955859+00:00"}