{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2023:O6OLGN25FA4ZPQCMPHIOP45V53","short_pith_number":"pith:O6OLGN25","canonical_record":{"source":{"id":"2303.02094","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"eess.IV","submitted_at":"2023-03-03T17:24:39Z","cross_cats_sorted":["cs.CV"],"title_canon_sha256":"0f4444a8adf5d6104061886a1416718fffb2553a555c82bc35ececfa08080770","abstract_canon_sha256":"941c541e087a4245c866faf84cb80d4778903e9c2836487e0d50d5a070f8f04c"},"schema_version":"1.0"},"canonical_sha256":"779cb3375d283997c04c79d0e7f3b5eee0c2de00184f17e16ffc0949ee21af04","source":{"kind":"arxiv","id":"2303.02094","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2303.02094","created_at":"2026-07-05T05:47:52Z"},{"alias_kind":"arxiv_version","alias_value":"2303.02094v1","created_at":"2026-07-05T05:47:52Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2303.02094","created_at":"2026-07-05T05:47:52Z"},{"alias_kind":"pith_short_12","alias_value":"O6OLGN25FA4Z","created_at":"2026-07-05T05:47:52Z"},{"alias_kind":"pith_short_16","alias_value":"O6OLGN25FA4ZPQCM","created_at":"2026-07-05T05:47:52Z"},{"alias_kind":"pith_short_8","alias_value":"O6OLGN25","created_at":"2026-07-05T05:47:52Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2023:O6OLGN25FA4ZPQCMPHIOP45V53","target":"record","payload":{"canonical_record":{"source":{"id":"2303.02094","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"eess.IV","submitted_at":"2023-03-03T17:24:39Z","cross_cats_sorted":["cs.CV"],"title_canon_sha256":"0f4444a8adf5d6104061886a1416718fffb2553a555c82bc35ececfa08080770","abstract_canon_sha256":"941c541e087a4245c866faf84cb80d4778903e9c2836487e0d50d5a070f8f04c"},"schema_version":"1.0"},"canonical_sha256":"779cb3375d283997c04c79d0e7f3b5eee0c2de00184f17e16ffc0949ee21af04","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-07-05T05:47:52.497206Z","signature_b64":"WBcBKtKTuOJMv5roFJqTI7qn7QSylzrBmjq3sBtz3THXHKeQJZQYa/1PTx56omeTxzZ68YfNIU9p35cBXstXCA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"779cb3375d283997c04c79d0e7f3b5eee0c2de00184f17e16ffc0949ee21af04","last_reissued_at":"2026-07-05T05:47:52.496783Z","signature_status":"signed_v1","first_computed_at":"2026-07-05T05:47:52.496783Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"2303.02094","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T05:47:52Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"tHFALIalN61DeqmBWM9brxeqaaLcidqqg7StgXiLXUWst0qDvN7BXTwCEWixb8Q8c2t24ZxQW6m2/VzoFv+xBw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-04T03:06:20.692729Z"},"content_sha256":"04630782669639cc867d30aaa4ff63831edb880b7b5d904000777f402429f07f","schema_version":"1.0","event_id":"sha256:04630782669639cc867d30aaa4ff63831edb880b7b5d904000777f402429f07f"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2023:O6OLGN25FA4ZPQCMPHIOP45V53","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Bi-parametric prostate MR image synthesis using pathology and sequence-conditioned stable diffusion","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["cs.CV"],"primary_cat":"eess.IV","authors_text":"Dean C. Barratt, Mark Emberton, Matthew J. Clarkson, Qianye Yang, Shaheer U. Saeed, Shonit Punwani, Tom Syer, Wen Yan, Yipeng Hu","submitted_at":"2023-03-03T17:24:39Z","abstract_excerpt":"We propose an image synthesis mechanism for multi-sequence prostate MR images conditioned on text, to control lesion presence and sequence, as well as to generate paired bi-parametric images conditioned on images e.g. for generating diffusion-weighted MR from T2-weighted MR for paired data, which are two challenging tasks in pathological image synthesis. Our proposed mechanism utilises and builds upon the recent stable diffusion model by proposing image-based conditioning for paired data generation. We validate our method using 2D image slices from real suspected prostate cancer patients. The "},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2303.02094","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2303.02094/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T05:47:52Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"5e8IwsVInLmWZ2ZupGhzk3qlbYwic8uUA1q97Wo9xn2+ro9jLF9CrQo3MqsKZGE+pmtdQNHP0w89rNykep6xCw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-04T03:06:20.693398Z"},"content_sha256":"47b7e84d92e8ec5052c7bd838ca8e34c51b3da52c4bc5fadf3048e9b132295f5","schema_version":"1.0","event_id":"sha256:47b7e84d92e8ec5052c7bd838ca8e34c51b3da52c4bc5fadf3048e9b132295f5"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/O6OLGN25FA4ZPQCMPHIOP45V53/bundle.json","state_url":"https://pith.science/pith/O6OLGN25FA4ZPQCMPHIOP45V53/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/O6OLGN25FA4ZPQCMPHIOP45V53/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-08-04T03:06:20Z","links":{"resolver":"https://pith.science/pith/O6OLGN25FA4ZPQCMPHIOP45V53","bundle":"https://pith.science/pith/O6OLGN25FA4ZPQCMPHIOP45V53/bundle.json","state":"https://pith.science/pith/O6OLGN25FA4ZPQCMPHIOP45V53/state.json","well_known_bundle":"https://pith.science/.well-known/pith/O6OLGN25FA4ZPQCMPHIOP45V53/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2023:O6OLGN25FA4ZPQCMPHIOP45V53","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"941c541e087a4245c866faf84cb80d4778903e9c2836487e0d50d5a070f8f04c","cross_cats_sorted":["cs.CV"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"eess.IV","submitted_at":"2023-03-03T17:24:39Z","title_canon_sha256":"0f4444a8adf5d6104061886a1416718fffb2553a555c82bc35ececfa08080770"},"schema_version":"1.0","source":{"id":"2303.02094","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2303.02094","created_at":"2026-07-05T05:47:52Z"},{"alias_kind":"arxiv_version","alias_value":"2303.02094v1","created_at":"2026-07-05T05:47:52Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2303.02094","created_at":"2026-07-05T05:47:52Z"},{"alias_kind":"pith_short_12","alias_value":"O6OLGN25FA4Z","created_at":"2026-07-05T05:47:52Z"},{"alias_kind":"pith_short_16","alias_value":"O6OLGN25FA4ZPQCM","created_at":"2026-07-05T05:47:52Z"},{"alias_kind":"pith_short_8","alias_value":"O6OLGN25","created_at":"2026-07-05T05:47:52Z"}],"graph_snapshots":[{"event_id":"sha256:47b7e84d92e8ec5052c7bd838ca8e34c51b3da52c4bc5fadf3048e9b132295f5","target":"graph","created_at":"2026-07-05T05:47:52Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2303.02094/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"We propose an image synthesis mechanism for multi-sequence prostate MR images conditioned on text, to control lesion presence and sequence, as well as to generate paired bi-parametric images conditioned on images e.g. for generating diffusion-weighted MR from T2-weighted MR for paired data, which are two challenging tasks in pathological image synthesis. Our proposed mechanism utilises and builds upon the recent stable diffusion model by proposing image-based conditioning for paired data generation. We validate our method using 2D image slices from real suspected prostate cancer patients. The ","authors_text":"Dean C. Barratt, Mark Emberton, Matthew J. Clarkson, Qianye Yang, Shaheer U. Saeed, Shonit Punwani, Tom Syer, Wen Yan, Yipeng Hu","cross_cats":["cs.CV"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"eess.IV","submitted_at":"2023-03-03T17:24:39Z","title":"Bi-parametric prostate MR image synthesis using pathology and sequence-conditioned stable diffusion"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2303.02094","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:04630782669639cc867d30aaa4ff63831edb880b7b5d904000777f402429f07f","target":"record","created_at":"2026-07-05T05:47:52Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"941c541e087a4245c866faf84cb80d4778903e9c2836487e0d50d5a070f8f04c","cross_cats_sorted":["cs.CV"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"eess.IV","submitted_at":"2023-03-03T17:24:39Z","title_canon_sha256":"0f4444a8adf5d6104061886a1416718fffb2553a555c82bc35ececfa08080770"},"schema_version":"1.0","source":{"id":"2303.02094","kind":"arxiv","version":1}},"canonical_sha256":"779cb3375d283997c04c79d0e7f3b5eee0c2de00184f17e16ffc0949ee21af04","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"779cb3375d283997c04c79d0e7f3b5eee0c2de00184f17e16ffc0949ee21af04","first_computed_at":"2026-07-05T05:47:52.496783Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-05T05:47:52.496783Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"WBcBKtKTuOJMv5roFJqTI7qn7QSylzrBmjq3sBtz3THXHKeQJZQYa/1PTx56omeTxzZ68YfNIU9p35cBXstXCA==","signature_status":"signed_v1","signed_at":"2026-07-05T05:47:52.497206Z","signed_message":"canonical_sha256_bytes"},"source_id":"2303.02094","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:04630782669639cc867d30aaa4ff63831edb880b7b5d904000777f402429f07f","sha256:47b7e84d92e8ec5052c7bd838ca8e34c51b3da52c4bc5fadf3048e9b132295f5"],"state_sha256":"60cb2db5af1db83fd7eb163758b674a54ca28611bfd0d73591d123411a541de8"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"GhJzGwtk21Xj1qObmSQO6IIeHRwsWiFf24Zpt2RIlvnVMC0bWuFeoO5GZxbnlGMvR0XiXBJ+mDiftK24foerBg==","signed_message":"bundle_sha256_bytes","signed_at":"2026-08-04T03:06:20.697704Z","bundle_sha256":"cf214ffe4f000bdf7532ec28cdbc759c53454a220d1e72bb32753e53d0fe7fd3"}}