{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2018:OKQDVIG2MQK76OZECSS3TMWIDH","short_pith_number":"pith:OKQDVIG2","canonical_record":{"source":{"id":"1806.01453","kind":"arxiv","version":3},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"stat.ME","submitted_at":"2018-06-05T01:21:31Z","cross_cats_sorted":[],"title_canon_sha256":"6f1428b370d8dbbf7f1af99b4ba7a6f888ed21749540e342f0ced3a1cb546e01","abstract_canon_sha256":"c2ce15b3d423351db242b87cdaea2edfedd8926b60aff935c0208b4092d13b78"},"schema_version":"1.0"},"canonical_sha256":"72a03aa0da6415ff3b2414a5b9b2c819ecf621c29bc7e27dc912ab969cf6af73","source":{"kind":"arxiv","id":"1806.01453","version":3},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1806.01453","created_at":"2026-05-17T23:50:49Z"},{"alias_kind":"arxiv_version","alias_value":"1806.01453v3","created_at":"2026-05-17T23:50:49Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1806.01453","created_at":"2026-05-17T23:50:49Z"},{"alias_kind":"pith_short_12","alias_value":"OKQDVIG2MQK7","created_at":"2026-05-18T12:32:43Z"},{"alias_kind":"pith_short_16","alias_value":"OKQDVIG2MQK76OZE","created_at":"2026-05-18T12:32:43Z"},{"alias_kind":"pith_short_8","alias_value":"OKQDVIG2","created_at":"2026-05-18T12:32:43Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2018:OKQDVIG2MQK76OZECSS3TMWIDH","target":"record","payload":{"canonical_record":{"source":{"id":"1806.01453","kind":"arxiv","version":3},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"stat.ME","submitted_at":"2018-06-05T01:21:31Z","cross_cats_sorted":[],"title_canon_sha256":"6f1428b370d8dbbf7f1af99b4ba7a6f888ed21749540e342f0ced3a1cb546e01","abstract_canon_sha256":"c2ce15b3d423351db242b87cdaea2edfedd8926b60aff935c0208b4092d13b78"},"schema_version":"1.0"},"canonical_sha256":"72a03aa0da6415ff3b2414a5b9b2c819ecf621c29bc7e27dc912ab969cf6af73","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-17T23:50:49.160161Z","signature_b64":"wEU3zdL3HfEMejd1dHN2lYEtEN6AJqebroxMXNF3Zgj/IuoYx2jkemND6IXr360WKXkPBsLcnN14dchEhvI6Bw==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"72a03aa0da6415ff3b2414a5b9b2c819ecf621c29bc7e27dc912ab969cf6af73","last_reissued_at":"2026-05-17T23:50:49.159524Z","signature_status":"signed_v1","first_computed_at":"2026-05-17T23:50:49.159524Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1806.01453","source_version":3,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-17T23:50:49Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"WAaZHo0yEwq+1LNk1FCj9tVKpwm9dkr9Fss9yvhLUByijgxRLHBYhKC5xXJ4F97fidVNF8/mgbh/SCRgx6kPAg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-07T07:32:37.612247Z"},"content_sha256":"4a6b321aa813359e44ecee1a766ad98ac69487ebbc6f50fef93acfa9154e126b","schema_version":"1.0","event_id":"sha256:4a6b321aa813359e44ecee1a766ad98ac69487ebbc6f50fef93acfa9154e126b"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2018:OKQDVIG2MQK76OZECSS3TMWIDH","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Calibration for computer experiments with binary responses and application to cell adhesion study","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"stat.ME","authors_text":"C. F. Jeff Wu, Cheng Zhu, Chih-Li Sung, William Rittase, Ying Hung","submitted_at":"2018-06-05T01:21:31Z","abstract_excerpt":"Calibration refers to the estimation of unknown parameters which are present in computer experiments but not available in physical experiments. An accurate estimation of these parameters is important because it provides a scientific understanding of the underlying system which is not available in physical experiments. Most of the work in the literature is limited to the analysis of continuous responses. Motivated by a study of cell adhesion experiments, we propose a new calibration framework for binary responses. Its application to the T cell adhesion data provides insight into the unknown val"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1806.01453","kind":"arxiv","version":3},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-17T23:50:49Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"+rbQVOvzp85ha4FAKPkmFXd4QgWvti+zh5fPQOJzXOFhq4obHfZfsh5xh5kdv4BhJ36S0CH1hKJfnmChiKBJAw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-07T07:32:37.612928Z"},"content_sha256":"035a1e2632ea08c94de8f5cb5ab47dcc4ad8686bf3671b01a29cda9ca60fa642","schema_version":"1.0","event_id":"sha256:035a1e2632ea08c94de8f5cb5ab47dcc4ad8686bf3671b01a29cda9ca60fa642"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/OKQDVIG2MQK76OZECSS3TMWIDH/bundle.json","state_url":"https://pith.science/pith/OKQDVIG2MQK76OZECSS3TMWIDH/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/OKQDVIG2MQK76OZECSS3TMWIDH/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-06-07T07:32:37Z","links":{"resolver":"https://pith.science/pith/OKQDVIG2MQK76OZECSS3TMWIDH","bundle":"https://pith.science/pith/OKQDVIG2MQK76OZECSS3TMWIDH/bundle.json","state":"https://pith.science/pith/OKQDVIG2MQK76OZECSS3TMWIDH/state.json","well_known_bundle":"https://pith.science/.well-known/pith/OKQDVIG2MQK76OZECSS3TMWIDH/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2018:OKQDVIG2MQK76OZECSS3TMWIDH","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"c2ce15b3d423351db242b87cdaea2edfedd8926b60aff935c0208b4092d13b78","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"stat.ME","submitted_at":"2018-06-05T01:21:31Z","title_canon_sha256":"6f1428b370d8dbbf7f1af99b4ba7a6f888ed21749540e342f0ced3a1cb546e01"},"schema_version":"1.0","source":{"id":"1806.01453","kind":"arxiv","version":3}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1806.01453","created_at":"2026-05-17T23:50:49Z"},{"alias_kind":"arxiv_version","alias_value":"1806.01453v3","created_at":"2026-05-17T23:50:49Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1806.01453","created_at":"2026-05-17T23:50:49Z"},{"alias_kind":"pith_short_12","alias_value":"OKQDVIG2MQK7","created_at":"2026-05-18T12:32:43Z"},{"alias_kind":"pith_short_16","alias_value":"OKQDVIG2MQK76OZE","created_at":"2026-05-18T12:32:43Z"},{"alias_kind":"pith_short_8","alias_value":"OKQDVIG2","created_at":"2026-05-18T12:32:43Z"}],"graph_snapshots":[{"event_id":"sha256:035a1e2632ea08c94de8f5cb5ab47dcc4ad8686bf3671b01a29cda9ca60fa642","target":"graph","created_at":"2026-05-17T23:50:49Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"Calibration refers to the estimation of unknown parameters which are present in computer experiments but not available in physical experiments. An accurate estimation of these parameters is important because it provides a scientific understanding of the underlying system which is not available in physical experiments. Most of the work in the literature is limited to the analysis of continuous responses. Motivated by a study of cell adhesion experiments, we propose a new calibration framework for binary responses. Its application to the T cell adhesion data provides insight into the unknown val","authors_text":"C. F. Jeff Wu, Cheng Zhu, Chih-Li Sung, William Rittase, Ying Hung","cross_cats":[],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"stat.ME","submitted_at":"2018-06-05T01:21:31Z","title":"Calibration for computer experiments with binary responses and application to cell adhesion study"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1806.01453","kind":"arxiv","version":3},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:4a6b321aa813359e44ecee1a766ad98ac69487ebbc6f50fef93acfa9154e126b","target":"record","created_at":"2026-05-17T23:50:49Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"c2ce15b3d423351db242b87cdaea2edfedd8926b60aff935c0208b4092d13b78","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"stat.ME","submitted_at":"2018-06-05T01:21:31Z","title_canon_sha256":"6f1428b370d8dbbf7f1af99b4ba7a6f888ed21749540e342f0ced3a1cb546e01"},"schema_version":"1.0","source":{"id":"1806.01453","kind":"arxiv","version":3}},"canonical_sha256":"72a03aa0da6415ff3b2414a5b9b2c819ecf621c29bc7e27dc912ab969cf6af73","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"72a03aa0da6415ff3b2414a5b9b2c819ecf621c29bc7e27dc912ab969cf6af73","first_computed_at":"2026-05-17T23:50:49.159524Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-17T23:50:49.159524Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"wEU3zdL3HfEMejd1dHN2lYEtEN6AJqebroxMXNF3Zgj/IuoYx2jkemND6IXr360WKXkPBsLcnN14dchEhvI6Bw==","signature_status":"signed_v1","signed_at":"2026-05-17T23:50:49.160161Z","signed_message":"canonical_sha256_bytes"},"source_id":"1806.01453","source_kind":"arxiv","source_version":3}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:4a6b321aa813359e44ecee1a766ad98ac69487ebbc6f50fef93acfa9154e126b","sha256:035a1e2632ea08c94de8f5cb5ab47dcc4ad8686bf3671b01a29cda9ca60fa642"],"state_sha256":"8ebe522efa907f2f72dc679e08f88eb9731221dc498127e3904c99093d28da1a"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"GxxKMm/c9Hn4xDWjyjfF6z+Y9MeUQJ+AA/AfetBB+KYdZRteuCBK9isQ5PJK+MzW0Jv7R9XxI11I/WC2mhOKBA==","signed_message":"bundle_sha256_bytes","signed_at":"2026-06-07T07:32:37.615975Z","bundle_sha256":"dfa75d001e842ca8877077c1cf092a62c12e90a1469be16a8de5b769c889801b"}}