{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2011:OQXI4B4653YQCACEPWLVU5PPV2","short_pith_number":"pith:OQXI4B46","canonical_record":{"source":{"id":"1110.5265","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.OT","submitted_at":"2011-10-24T15:49:30Z","cross_cats_sorted":["cs.CE","q-bio.GN"],"title_canon_sha256":"15921d1ddad10ccee9596c7f41ade2747099cbeb132ee8d8408d62bb71db7509","abstract_canon_sha256":"8e20b9ef9c8f98a36b84fc90faa3c5712053f3683858532644bffd13bbf88526"},"schema_version":"1.0"},"canonical_sha256":"742e8e079eeef10100447d975a75efae8bc425545f14b655d2165a5e7ee4167e","source":{"kind":"arxiv","id":"1110.5265","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1110.5265","created_at":"2026-05-18T04:10:24Z"},{"alias_kind":"arxiv_version","alias_value":"1110.5265v1","created_at":"2026-05-18T04:10:24Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1110.5265","created_at":"2026-05-18T04:10:24Z"},{"alias_kind":"pith_short_12","alias_value":"OQXI4B4653YQ","created_at":"2026-05-18T12:26:37Z"},{"alias_kind":"pith_short_16","alias_value":"OQXI4B4653YQCACE","created_at":"2026-05-18T12:26:37Z"},{"alias_kind":"pith_short_8","alias_value":"OQXI4B46","created_at":"2026-05-18T12:26:37Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2011:OQXI4B4653YQCACEPWLVU5PPV2","target":"record","payload":{"canonical_record":{"source":{"id":"1110.5265","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.OT","submitted_at":"2011-10-24T15:49:30Z","cross_cats_sorted":["cs.CE","q-bio.GN"],"title_canon_sha256":"15921d1ddad10ccee9596c7f41ade2747099cbeb132ee8d8408d62bb71db7509","abstract_canon_sha256":"8e20b9ef9c8f98a36b84fc90faa3c5712053f3683858532644bffd13bbf88526"},"schema_version":"1.0"},"canonical_sha256":"742e8e079eeef10100447d975a75efae8bc425545f14b655d2165a5e7ee4167e","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T04:10:24.317457Z","signature_b64":"E9MhWa5OEUwaTl2EQDRdTfGTWaOVkxgBjpiLIklpmO6O6nYnusaAg8LJW7M4Kvuk5gWq59j4SNY02lPkYpumCA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"742e8e079eeef10100447d975a75efae8bc425545f14b655d2165a5e7ee4167e","last_reissued_at":"2026-05-18T04:10:24.316916Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T04:10:24.316916Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1110.5265","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T04:10:24Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"nbmhGPdfKC70sn0PlIKH1j+YNxp/9xxi86ouC7MepYWh2VVZlK/b55XaKzxl3JPKPP7kqsZWznaZJ9NvOpwaCw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-30T03:59:42.480843Z"},"content_sha256":"4db75975ad3abe1685de6c666bc13304daa1fbdd0bfbbf44c218f0647aa49105","schema_version":"1.0","event_id":"sha256:4db75975ad3abe1685de6c666bc13304daa1fbdd0bfbbf44c218f0647aa49105"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2011:OQXI4B4653YQCACEPWLVU5PPV2","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"On Programs and Genomes","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["cs.CE","q-bio.GN"],"primary_cat":"q-bio.OT","authors_text":"Eric Werner","submitted_at":"2011-10-24T15:49:30Z","abstract_excerpt":"We outline the global control architecture of genomes. A theory of genomic control information is presented. The concept of a developmental control network called a cene (for control gene) is introduced. We distinguish parts-genes from control genes or cenes. Cenes are interpreted and executed by the cell and, thereby, direct cell actions including communication, growth, division, differentiation and multi-cellular development. The cenome is the global developmental control network in the genome. The cenome is also a cene that consists of interlinked sub-cenes that guide the ontogeny of the or"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1110.5265","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T04:10:24Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"Epnp0NMQHUg5IQT7bBWRXbglQNDlgtm9PiwpmHJydwAlq1abVoyHcLzCtHE/MTtYzpHF7hQ4sNkuQQhMZ7eQDQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-30T03:59:42.481450Z"},"content_sha256":"f8bb56ec742b91f9141fb40baea10390eb9568a3940070ca7557e3c150d1c296","schema_version":"1.0","event_id":"sha256:f8bb56ec742b91f9141fb40baea10390eb9568a3940070ca7557e3c150d1c296"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/OQXI4B4653YQCACEPWLVU5PPV2/bundle.json","state_url":"https://pith.science/pith/OQXI4B4653YQCACEPWLVU5PPV2/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/OQXI4B4653YQCACEPWLVU5PPV2/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-06-30T03:59:42Z","links":{"resolver":"https://pith.science/pith/OQXI4B4653YQCACEPWLVU5PPV2","bundle":"https://pith.science/pith/OQXI4B4653YQCACEPWLVU5PPV2/bundle.json","state":"https://pith.science/pith/OQXI4B4653YQCACEPWLVU5PPV2/state.json","well_known_bundle":"https://pith.science/.well-known/pith/OQXI4B4653YQCACEPWLVU5PPV2/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2011:OQXI4B4653YQCACEPWLVU5PPV2","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"8e20b9ef9c8f98a36b84fc90faa3c5712053f3683858532644bffd13bbf88526","cross_cats_sorted":["cs.CE","q-bio.GN"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.OT","submitted_at":"2011-10-24T15:49:30Z","title_canon_sha256":"15921d1ddad10ccee9596c7f41ade2747099cbeb132ee8d8408d62bb71db7509"},"schema_version":"1.0","source":{"id":"1110.5265","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1110.5265","created_at":"2026-05-18T04:10:24Z"},{"alias_kind":"arxiv_version","alias_value":"1110.5265v1","created_at":"2026-05-18T04:10:24Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1110.5265","created_at":"2026-05-18T04:10:24Z"},{"alias_kind":"pith_short_12","alias_value":"OQXI4B4653YQ","created_at":"2026-05-18T12:26:37Z"},{"alias_kind":"pith_short_16","alias_value":"OQXI4B4653YQCACE","created_at":"2026-05-18T12:26:37Z"},{"alias_kind":"pith_short_8","alias_value":"OQXI4B46","created_at":"2026-05-18T12:26:37Z"}],"graph_snapshots":[{"event_id":"sha256:f8bb56ec742b91f9141fb40baea10390eb9568a3940070ca7557e3c150d1c296","target":"graph","created_at":"2026-05-18T04:10:24Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"We outline the global control architecture of genomes. A theory of genomic control information is presented. The concept of a developmental control network called a cene (for control gene) is introduced. We distinguish parts-genes from control genes or cenes. Cenes are interpreted and executed by the cell and, thereby, direct cell actions including communication, growth, division, differentiation and multi-cellular development. The cenome is the global developmental control network in the genome. The cenome is also a cene that consists of interlinked sub-cenes that guide the ontogeny of the or","authors_text":"Eric Werner","cross_cats":["cs.CE","q-bio.GN"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.OT","submitted_at":"2011-10-24T15:49:30Z","title":"On Programs and Genomes"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1110.5265","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:4db75975ad3abe1685de6c666bc13304daa1fbdd0bfbbf44c218f0647aa49105","target":"record","created_at":"2026-05-18T04:10:24Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"8e20b9ef9c8f98a36b84fc90faa3c5712053f3683858532644bffd13bbf88526","cross_cats_sorted":["cs.CE","q-bio.GN"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.OT","submitted_at":"2011-10-24T15:49:30Z","title_canon_sha256":"15921d1ddad10ccee9596c7f41ade2747099cbeb132ee8d8408d62bb71db7509"},"schema_version":"1.0","source":{"id":"1110.5265","kind":"arxiv","version":1}},"canonical_sha256":"742e8e079eeef10100447d975a75efae8bc425545f14b655d2165a5e7ee4167e","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"742e8e079eeef10100447d975a75efae8bc425545f14b655d2165a5e7ee4167e","first_computed_at":"2026-05-18T04:10:24.316916Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T04:10:24.316916Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"E9MhWa5OEUwaTl2EQDRdTfGTWaOVkxgBjpiLIklpmO6O6nYnusaAg8LJW7M4Kvuk5gWq59j4SNY02lPkYpumCA==","signature_status":"signed_v1","signed_at":"2026-05-18T04:10:24.317457Z","signed_message":"canonical_sha256_bytes"},"source_id":"1110.5265","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:4db75975ad3abe1685de6c666bc13304daa1fbdd0bfbbf44c218f0647aa49105","sha256:f8bb56ec742b91f9141fb40baea10390eb9568a3940070ca7557e3c150d1c296"],"state_sha256":"dd4495d8c4e0d678770010f24d150cfb2f6d1a0367eb0342cdc0a45d4713ac78"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"ZyVQiniIbf0oj1mbCSIwKGjvRrT7W0IbW3ASUsT6Q5kqJCE+vW0oOP7QmBU2oWHHN8DjN0Ag5YF8n5e4R+7FBQ==","signed_message":"bundle_sha256_bytes","signed_at":"2026-06-30T03:59:42.484345Z","bundle_sha256":"fb2969f536128545d276513ffe131fab59110a0f3074a9981bfab0197f435966"}}