{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2014:OX6XHFF2QEPE3SR4FD4MLXC6AD","short_pith_number":"pith:OX6XHFF2","canonical_record":{"source":{"id":"1404.0270","kind":"arxiv","version":2},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.BM","submitted_at":"2014-04-01T15:16:23Z","cross_cats_sorted":[],"title_canon_sha256":"6b1913879a72272375e621eddb6654f725dda9fd0a087c50d85870009f5220d2","abstract_canon_sha256":"e10f6314cc24562df92368b5d405c6a6deeac76995608136154d66d00773a56c"},"schema_version":"1.0"},"canonical_sha256":"75fd7394ba811e4dca3c28f8c5dc5e00f61b6e18bc8839a34d48617b2a8cd58f","source":{"kind":"arxiv","id":"1404.0270","version":2},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1404.0270","created_at":"2026-05-18T02:43:18Z"},{"alias_kind":"arxiv_version","alias_value":"1404.0270v2","created_at":"2026-05-18T02:43:18Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1404.0270","created_at":"2026-05-18T02:43:18Z"},{"alias_kind":"pith_short_12","alias_value":"OX6XHFF2QEPE","created_at":"2026-05-18T12:28:43Z"},{"alias_kind":"pith_short_16","alias_value":"OX6XHFF2QEPE3SR4","created_at":"2026-05-18T12:28:43Z"},{"alias_kind":"pith_short_8","alias_value":"OX6XHFF2","created_at":"2026-05-18T12:28:43Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2014:OX6XHFF2QEPE3SR4FD4MLXC6AD","target":"record","payload":{"canonical_record":{"source":{"id":"1404.0270","kind":"arxiv","version":2},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.BM","submitted_at":"2014-04-01T15:16:23Z","cross_cats_sorted":[],"title_canon_sha256":"6b1913879a72272375e621eddb6654f725dda9fd0a087c50d85870009f5220d2","abstract_canon_sha256":"e10f6314cc24562df92368b5d405c6a6deeac76995608136154d66d00773a56c"},"schema_version":"1.0"},"canonical_sha256":"75fd7394ba811e4dca3c28f8c5dc5e00f61b6e18bc8839a34d48617b2a8cd58f","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T02:43:18.942287Z","signature_b64":"7y5iuFepx14ghz4tVtWZxt94cNNvZv4npHxF2/YK0vqK1RoPKDwvvnqLFHU57jKRqj5q96cYp9tZFIWH+U0CCA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"75fd7394ba811e4dca3c28f8c5dc5e00f61b6e18bc8839a34d48617b2a8cd58f","last_reissued_at":"2026-05-18T02:43:18.941607Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T02:43:18.941607Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1404.0270","source_version":2,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T02:43:18Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"8Z+Eb4k2kKVdxZsD/08QijIRTBIahFPu/7XAAMTUaGqzIOctWJMuowWPhy8ilhl9tujEzBZkd16nVk9WZwfhAA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-01T10:24:55.205489Z"},"content_sha256":"ce6bd28dd7f2c3ab456e5917c540dcb3bb607ce5b47b8aa263f82a8b2a3c1f6d","schema_version":"1.0","event_id":"sha256:ce6bd28dd7f2c3ab456e5917c540dcb3bb607ce5b47b8aa263f82a8b2a3c1f6d"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2014:OX6XHFF2QEPE3SR4FD4MLXC6AD","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Memory efficient RNA energy landscape exploration","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"q-bio.BM","authors_text":"Christoph Flamm, Marcel Kucharik, Martin Mann, Michael T. Wolfinger","submitted_at":"2014-04-01T15:16:23Z","abstract_excerpt":"Energy landscapes provide a valuable means for studying the folding dynamics of short RNA molecules in detail by modeling all possible structures and their transitions. Higher abstraction levels based on a macro-state decomposition of the landscape enable the study of larger systems, however they are still restricted by huge memory requirements of exact approaches.\n  We present a highly parallelizable local enumeration scheme that enables the computation of exact macro-state transition models with highly reduced memory requirements. The approach is evaluated on RNA secondary structure landscap"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1404.0270","kind":"arxiv","version":2},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T02:43:18Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"Wktqe4gzJItsy13JN5UmMBh4NSEQbT3FfyXpILGkD7fIa0wn3FoJFxYVg2TJyrJB+RwYEbyVSruT5BEc4IhkCg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-01T10:24:55.205838Z"},"content_sha256":"9df8cf39b3c17cf7b8c71a2eaf546ccd183dde626aaba24109f9bbca6a8fde5f","schema_version":"1.0","event_id":"sha256:9df8cf39b3c17cf7b8c71a2eaf546ccd183dde626aaba24109f9bbca6a8fde5f"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/OX6XHFF2QEPE3SR4FD4MLXC6AD/bundle.json","state_url":"https://pith.science/pith/OX6XHFF2QEPE3SR4FD4MLXC6AD/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/OX6XHFF2QEPE3SR4FD4MLXC6AD/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-06-01T10:24:55Z","links":{"resolver":"https://pith.science/pith/OX6XHFF2QEPE3SR4FD4MLXC6AD","bundle":"https://pith.science/pith/OX6XHFF2QEPE3SR4FD4MLXC6AD/bundle.json","state":"https://pith.science/pith/OX6XHFF2QEPE3SR4FD4MLXC6AD/state.json","well_known_bundle":"https://pith.science/.well-known/pith/OX6XHFF2QEPE3SR4FD4MLXC6AD/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2014:OX6XHFF2QEPE3SR4FD4MLXC6AD","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"e10f6314cc24562df92368b5d405c6a6deeac76995608136154d66d00773a56c","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.BM","submitted_at":"2014-04-01T15:16:23Z","title_canon_sha256":"6b1913879a72272375e621eddb6654f725dda9fd0a087c50d85870009f5220d2"},"schema_version":"1.0","source":{"id":"1404.0270","kind":"arxiv","version":2}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1404.0270","created_at":"2026-05-18T02:43:18Z"},{"alias_kind":"arxiv_version","alias_value":"1404.0270v2","created_at":"2026-05-18T02:43:18Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1404.0270","created_at":"2026-05-18T02:43:18Z"},{"alias_kind":"pith_short_12","alias_value":"OX6XHFF2QEPE","created_at":"2026-05-18T12:28:43Z"},{"alias_kind":"pith_short_16","alias_value":"OX6XHFF2QEPE3SR4","created_at":"2026-05-18T12:28:43Z"},{"alias_kind":"pith_short_8","alias_value":"OX6XHFF2","created_at":"2026-05-18T12:28:43Z"}],"graph_snapshots":[{"event_id":"sha256:9df8cf39b3c17cf7b8c71a2eaf546ccd183dde626aaba24109f9bbca6a8fde5f","target":"graph","created_at":"2026-05-18T02:43:18Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"Energy landscapes provide a valuable means for studying the folding dynamics of short RNA molecules in detail by modeling all possible structures and their transitions. Higher abstraction levels based on a macro-state decomposition of the landscape enable the study of larger systems, however they are still restricted by huge memory requirements of exact approaches.\n  We present a highly parallelizable local enumeration scheme that enables the computation of exact macro-state transition models with highly reduced memory requirements. The approach is evaluated on RNA secondary structure landscap","authors_text":"Christoph Flamm, Marcel Kucharik, Martin Mann, Michael T. Wolfinger","cross_cats":[],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.BM","submitted_at":"2014-04-01T15:16:23Z","title":"Memory efficient RNA energy landscape exploration"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1404.0270","kind":"arxiv","version":2},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:ce6bd28dd7f2c3ab456e5917c540dcb3bb607ce5b47b8aa263f82a8b2a3c1f6d","target":"record","created_at":"2026-05-18T02:43:18Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"e10f6314cc24562df92368b5d405c6a6deeac76995608136154d66d00773a56c","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.BM","submitted_at":"2014-04-01T15:16:23Z","title_canon_sha256":"6b1913879a72272375e621eddb6654f725dda9fd0a087c50d85870009f5220d2"},"schema_version":"1.0","source":{"id":"1404.0270","kind":"arxiv","version":2}},"canonical_sha256":"75fd7394ba811e4dca3c28f8c5dc5e00f61b6e18bc8839a34d48617b2a8cd58f","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"75fd7394ba811e4dca3c28f8c5dc5e00f61b6e18bc8839a34d48617b2a8cd58f","first_computed_at":"2026-05-18T02:43:18.941607Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T02:43:18.941607Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"7y5iuFepx14ghz4tVtWZxt94cNNvZv4npHxF2/YK0vqK1RoPKDwvvnqLFHU57jKRqj5q96cYp9tZFIWH+U0CCA==","signature_status":"signed_v1","signed_at":"2026-05-18T02:43:18.942287Z","signed_message":"canonical_sha256_bytes"},"source_id":"1404.0270","source_kind":"arxiv","source_version":2}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:ce6bd28dd7f2c3ab456e5917c540dcb3bb607ce5b47b8aa263f82a8b2a3c1f6d","sha256:9df8cf39b3c17cf7b8c71a2eaf546ccd183dde626aaba24109f9bbca6a8fde5f"],"state_sha256":"ed91d7b155f21a9098b3e720adbfe0db12dc9068d5c3ff8df0f8721c1620f31d"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"wUDN+rlbBcBDttua+ul11Akb1LJURxX2naqAkNl7KO7gEAutED6bniXSHhNWPHD1w46bUPvwVmgViko2sJHjDw==","signed_message":"bundle_sha256_bytes","signed_at":"2026-06-01T10:24:55.207847Z","bundle_sha256":"8727c1790fb93a6c5a1c0706d4c1115fbea56ad4876dce5c459895d14affe44e"}}