{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2018:PA5PLSEIO6CIABXETDEJAGQHE6","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"d0ff9e822a89320a5d623df020af238024d266f3809ba4fb10280a03cdbd2b31","cross_cats_sorted":["math.CO"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.PE","submitted_at":"2018-01-11T19:48:30Z","title_canon_sha256":"29c7cda673ee49ebfe0afcc0a0af7a657bbf8d590ef8ee98b5465ce0a3937084"},"schema_version":"1.0","source":{"id":"1801.05056","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1801.05056","created_at":"2026-05-18T00:25:50Z"},{"alias_kind":"arxiv_version","alias_value":"1801.05056v1","created_at":"2026-05-18T00:25:50Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1801.05056","created_at":"2026-05-18T00:25:50Z"},{"alias_kind":"pith_short_12","alias_value":"PA5PLSEIO6CI","created_at":"2026-05-18T12:32:43Z"},{"alias_kind":"pith_short_16","alias_value":"PA5PLSEIO6CIABXE","created_at":"2026-05-18T12:32:43Z"},{"alias_kind":"pith_short_8","alias_value":"PA5PLSEI","created_at":"2026-05-18T12:32:43Z"}],"graph_snapshots":[{"event_id":"sha256:2af02430e13788ea19860de44080d3f03bd534b07eed094bd1baf81e844c0f6c","target":"graph","created_at":"2026-05-18T00:25:50Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"Genetic robustness, the preservation of evolved phenotypes against genotypic mutations, is one of the central concepts in evolution. In recent years a large body of work has focused on the origins, mechanisms, and consequences of robustness in a wide range of biological systems. In particular, research on ncRNAs studied the ability of sequences to maintain folded structures against single-point mutations. In these studies, the structure is merely a reference. However, recent work revealed evidence that structure itself contributes to the genetic robustness of ncRNAs. We follow this line of tho","authors_text":"Christian M. Reidys, Christopher Barrett, Fenix W. Huang, Qijun He","cross_cats":["math.CO"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.PE","submitted_at":"2018-01-11T19:48:30Z","title":"Genetic robustness of let-7 miRNA sequence-structure pairs"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1801.05056","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:f0b2dab1f5a15917cbd5f85e52024788114b16ef03c7392ea0351d3dca76560c","target":"record","created_at":"2026-05-18T00:25:50Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"d0ff9e822a89320a5d623df020af238024d266f3809ba4fb10280a03cdbd2b31","cross_cats_sorted":["math.CO"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.PE","submitted_at":"2018-01-11T19:48:30Z","title_canon_sha256":"29c7cda673ee49ebfe0afcc0a0af7a657bbf8d590ef8ee98b5465ce0a3937084"},"schema_version":"1.0","source":{"id":"1801.05056","kind":"arxiv","version":1}},"canonical_sha256":"783af5c88877848006e498c8901a0727b86137e1c35b249efc13752b5f01be2b","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"783af5c88877848006e498c8901a0727b86137e1c35b249efc13752b5f01be2b","first_computed_at":"2026-05-18T00:25:50.136909Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T00:25:50.136909Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"xufxB9IBd549aPSnDISS+Tny3ToqOEi+74f241wJ2JawsHknowM7+AtCeOAUYOS8zLLIVz1sMYmvu+EymxoqAw==","signature_status":"signed_v1","signed_at":"2026-05-18T00:25:50.137526Z","signed_message":"canonical_sha256_bytes"},"source_id":"1801.05056","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:f0b2dab1f5a15917cbd5f85e52024788114b16ef03c7392ea0351d3dca76560c","sha256:2af02430e13788ea19860de44080d3f03bd534b07eed094bd1baf81e844c0f6c"],"state_sha256":"1dde06900dc593738c0a6203e42704a3ac4e8f0c0cd254de5743965657b78686"}