{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2012:PBVVSA7G7HVUGWKVRF2XN6LH2J","short_pith_number":"pith:PBVVSA7G","canonical_record":{"source":{"id":"1203.2199","kind":"arxiv","version":2},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2012-03-09T22:28:27Z","cross_cats_sorted":["math-ph","math.MP","physics.bio-ph"],"title_canon_sha256":"e417173362a0421601fa273700e0bcb24079269b1a808abbdbfec23b55197485","abstract_canon_sha256":"c4e6b294185fa385f19ae1fe8f6039245732e904f4b6a893df8a847149880b9f"},"schema_version":"1.0"},"canonical_sha256":"786b5903e6f9eb435955897576f967d2676ad7244ea3dec839b5c275cd1e6b95","source":{"kind":"arxiv","id":"1203.2199","version":2},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1203.2199","created_at":"2026-05-18T03:22:51Z"},{"alias_kind":"arxiv_version","alias_value":"1203.2199v2","created_at":"2026-05-18T03:22:51Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1203.2199","created_at":"2026-05-18T03:22:51Z"},{"alias_kind":"pith_short_12","alias_value":"PBVVSA7G7HVU","created_at":"2026-05-18T12:27:18Z"},{"alias_kind":"pith_short_16","alias_value":"PBVVSA7G7HVUGWKV","created_at":"2026-05-18T12:27:18Z"},{"alias_kind":"pith_short_8","alias_value":"PBVVSA7G","created_at":"2026-05-18T12:27:18Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2012:PBVVSA7G7HVUGWKVRF2XN6LH2J","target":"record","payload":{"canonical_record":{"source":{"id":"1203.2199","kind":"arxiv","version":2},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2012-03-09T22:28:27Z","cross_cats_sorted":["math-ph","math.MP","physics.bio-ph"],"title_canon_sha256":"e417173362a0421601fa273700e0bcb24079269b1a808abbdbfec23b55197485","abstract_canon_sha256":"c4e6b294185fa385f19ae1fe8f6039245732e904f4b6a893df8a847149880b9f"},"schema_version":"1.0"},"canonical_sha256":"786b5903e6f9eb435955897576f967d2676ad7244ea3dec839b5c275cd1e6b95","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T03:22:51.599932Z","signature_b64":"aCFPXY3upU4dV6p+981dA6FHxbp/ih1K5pnFf2hd4KjWj0U77dYdbtMEog5jVcpT833oDO8oSf4bU5QPfcr6Dg==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"786b5903e6f9eb435955897576f967d2676ad7244ea3dec839b5c275cd1e6b95","last_reissued_at":"2026-05-18T03:22:51.599064Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T03:22:51.599064Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1203.2199","source_version":2,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T03:22:51Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"vxXiZVBXGy4ZnNOrGXCGqmYUcypSVvNVwxe8zBtcuJiwDHOfZG98M1vNjBWgCy7DJSmJOkXEy/CM0vBGvFwrDQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-06T15:08:09.866774Z"},"content_sha256":"d09dde80a9046671f95c1f9a190c0f3fa86a9e042072ff707b7ff1fc1a7aed95","schema_version":"1.0","event_id":"sha256:d09dde80a9046671f95c1f9a190c0f3fa86a9e042072ff707b7ff1fc1a7aed95"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2012:PBVVSA7G7HVUGWKVRF2XN6LH2J","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Critical Casimir forces in cellular membranes","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["math-ph","math.MP","physics.bio-ph"],"primary_cat":"q-bio.QM","authors_text":"Benjamin B. Machta, James P. Sethna, Sarah L. Veatch","submitted_at":"2012-03-09T22:28:27Z","abstract_excerpt":"Recent experiments suggest that membranes of living cells are tuned close to a miscibility critical point in the 2D Ising universality class. We propose that one role for this proximity to criticality in live cells is to provide a conduit for relatively long-ranged critical Casimir forces. Using techniques from conformal field theory we calculate potentials of mean force between membrane bound inclusions mediated by their local interactions with the composition order parameter. We verify these calculations using Monte-Carlo where we also compare critical and off-critical results. Our findings "},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1203.2199","kind":"arxiv","version":2},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T03:22:51Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"J8CqL7B9mQaSnLMZ2JTKGV3uuZWUIiWb+u8DbDQ6pnmsaz+EFke3uq3Gii/fPxB8Sa5MuEexPvuiDNy5DDmHCA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-06T15:08:09.867544Z"},"content_sha256":"bbf1e5182faf92a73ed94c45e18fc2b52c351d347eec4e29bd65314b5bfa4236","schema_version":"1.0","event_id":"sha256:bbf1e5182faf92a73ed94c45e18fc2b52c351d347eec4e29bd65314b5bfa4236"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/PBVVSA7G7HVUGWKVRF2XN6LH2J/bundle.json","state_url":"https://pith.science/pith/PBVVSA7G7HVUGWKVRF2XN6LH2J/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/PBVVSA7G7HVUGWKVRF2XN6LH2J/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-06-06T15:08:09Z","links":{"resolver":"https://pith.science/pith/PBVVSA7G7HVUGWKVRF2XN6LH2J","bundle":"https://pith.science/pith/PBVVSA7G7HVUGWKVRF2XN6LH2J/bundle.json","state":"https://pith.science/pith/PBVVSA7G7HVUGWKVRF2XN6LH2J/state.json","well_known_bundle":"https://pith.science/.well-known/pith/PBVVSA7G7HVUGWKVRF2XN6LH2J/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2012:PBVVSA7G7HVUGWKVRF2XN6LH2J","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"c4e6b294185fa385f19ae1fe8f6039245732e904f4b6a893df8a847149880b9f","cross_cats_sorted":["math-ph","math.MP","physics.bio-ph"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2012-03-09T22:28:27Z","title_canon_sha256":"e417173362a0421601fa273700e0bcb24079269b1a808abbdbfec23b55197485"},"schema_version":"1.0","source":{"id":"1203.2199","kind":"arxiv","version":2}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1203.2199","created_at":"2026-05-18T03:22:51Z"},{"alias_kind":"arxiv_version","alias_value":"1203.2199v2","created_at":"2026-05-18T03:22:51Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1203.2199","created_at":"2026-05-18T03:22:51Z"},{"alias_kind":"pith_short_12","alias_value":"PBVVSA7G7HVU","created_at":"2026-05-18T12:27:18Z"},{"alias_kind":"pith_short_16","alias_value":"PBVVSA7G7HVUGWKV","created_at":"2026-05-18T12:27:18Z"},{"alias_kind":"pith_short_8","alias_value":"PBVVSA7G","created_at":"2026-05-18T12:27:18Z"}],"graph_snapshots":[{"event_id":"sha256:bbf1e5182faf92a73ed94c45e18fc2b52c351d347eec4e29bd65314b5bfa4236","target":"graph","created_at":"2026-05-18T03:22:51Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"Recent experiments suggest that membranes of living cells are tuned close to a miscibility critical point in the 2D Ising universality class. We propose that one role for this proximity to criticality in live cells is to provide a conduit for relatively long-ranged critical Casimir forces. Using techniques from conformal field theory we calculate potentials of mean force between membrane bound inclusions mediated by their local interactions with the composition order parameter. We verify these calculations using Monte-Carlo where we also compare critical and off-critical results. Our findings ","authors_text":"Benjamin B. Machta, James P. Sethna, Sarah L. Veatch","cross_cats":["math-ph","math.MP","physics.bio-ph"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2012-03-09T22:28:27Z","title":"Critical Casimir forces in cellular membranes"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1203.2199","kind":"arxiv","version":2},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:d09dde80a9046671f95c1f9a190c0f3fa86a9e042072ff707b7ff1fc1a7aed95","target":"record","created_at":"2026-05-18T03:22:51Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"c4e6b294185fa385f19ae1fe8f6039245732e904f4b6a893df8a847149880b9f","cross_cats_sorted":["math-ph","math.MP","physics.bio-ph"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2012-03-09T22:28:27Z","title_canon_sha256":"e417173362a0421601fa273700e0bcb24079269b1a808abbdbfec23b55197485"},"schema_version":"1.0","source":{"id":"1203.2199","kind":"arxiv","version":2}},"canonical_sha256":"786b5903e6f9eb435955897576f967d2676ad7244ea3dec839b5c275cd1e6b95","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"786b5903e6f9eb435955897576f967d2676ad7244ea3dec839b5c275cd1e6b95","first_computed_at":"2026-05-18T03:22:51.599064Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T03:22:51.599064Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"aCFPXY3upU4dV6p+981dA6FHxbp/ih1K5pnFf2hd4KjWj0U77dYdbtMEog5jVcpT833oDO8oSf4bU5QPfcr6Dg==","signature_status":"signed_v1","signed_at":"2026-05-18T03:22:51.599932Z","signed_message":"canonical_sha256_bytes"},"source_id":"1203.2199","source_kind":"arxiv","source_version":2}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:d09dde80a9046671f95c1f9a190c0f3fa86a9e042072ff707b7ff1fc1a7aed95","sha256:bbf1e5182faf92a73ed94c45e18fc2b52c351d347eec4e29bd65314b5bfa4236"],"state_sha256":"ca3bbd59720d801a19764104e6f5ae88a185b7ebc0b81fc6ce9658e367e01c05"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"fIWEx4Yxek9NPvZHzE/FbnvKSSIdiggn0yjkhGiGrLMmsTiA2qXLHQ7E7GuisrMAst2BpScdWboNt3A+0eJyAw==","signed_message":"bundle_sha256_bytes","signed_at":"2026-06-06T15:08:09.871054Z","bundle_sha256":"f6ed90100dee7e97296e0fbf30d765b47477f3bd79f0821840220fd13a56fa49"}}