{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2014:PIC7HQHLHU43OH5MFZ4EUOSD65","short_pith_number":"pith:PIC7HQHL","canonical_record":{"source":{"id":"1406.6731","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2014-06-25T23:03:25Z","cross_cats_sorted":["q-bio.CB","q-bio.MN"],"title_canon_sha256":"26e68ac1f143d9b1646a8d7bcbbd7ebd2c88cfe2e84228dd3844ab9f4f995b6a","abstract_canon_sha256":"17db57995248e5ded9167cc98c61c756e63105ff2449dc7a6b57a1bd0cad5720"},"schema_version":"1.0"},"canonical_sha256":"7a05f3c0eb3d39b71fac2e784a3a43f77b762fb13a1ea49731ab9abef253dcfb","source":{"kind":"arxiv","id":"1406.6731","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1406.6731","created_at":"2026-05-18T02:48:56Z"},{"alias_kind":"arxiv_version","alias_value":"1406.6731v1","created_at":"2026-05-18T02:48:56Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1406.6731","created_at":"2026-05-18T02:48:56Z"},{"alias_kind":"pith_short_12","alias_value":"PIC7HQHLHU43","created_at":"2026-05-18T12:28:43Z"},{"alias_kind":"pith_short_16","alias_value":"PIC7HQHLHU43OH5M","created_at":"2026-05-18T12:28:43Z"},{"alias_kind":"pith_short_8","alias_value":"PIC7HQHL","created_at":"2026-05-18T12:28:43Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2014:PIC7HQHLHU43OH5MFZ4EUOSD65","target":"record","payload":{"canonical_record":{"source":{"id":"1406.6731","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2014-06-25T23:03:25Z","cross_cats_sorted":["q-bio.CB","q-bio.MN"],"title_canon_sha256":"26e68ac1f143d9b1646a8d7bcbbd7ebd2c88cfe2e84228dd3844ab9f4f995b6a","abstract_canon_sha256":"17db57995248e5ded9167cc98c61c756e63105ff2449dc7a6b57a1bd0cad5720"},"schema_version":"1.0"},"canonical_sha256":"7a05f3c0eb3d39b71fac2e784a3a43f77b762fb13a1ea49731ab9abef253dcfb","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T02:48:56.031754Z","signature_b64":"KFyORc1MBSlFdk9BfGqF5PA+iECGoc/s3H5GmK+aZypfujAuFiy/M2YKmdUCDDqECHjNBYTZb5lgbWSfoVnCCg==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"7a05f3c0eb3d39b71fac2e784a3a43f77b762fb13a1ea49731ab9abef253dcfb","last_reissued_at":"2026-05-18T02:48:56.031094Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T02:48:56.031094Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1406.6731","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T02:48:56Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"4MeRndZlEFWQftO1OfELJSgDOiHuulUCWtmoX+axmQGpAA74MN3cZw2ODVLJspxqQfcZNpqV6mMU4tzjy6ViAA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-01T00:36:01.636247Z"},"content_sha256":"695928f5fabdecefd622c7c320712ba1cde1268daa789869ecdf3642783dc0f2","schema_version":"1.0","event_id":"sha256:695928f5fabdecefd622c7c320712ba1cde1268daa789869ecdf3642783dc0f2"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2014:PIC7HQHLHU43OH5MFZ4EUOSD65","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"From Intracellular Signaling to Population Oscillations: Bridging Scales in Collective Behavior","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["q-bio.CB","q-bio.MN"],"primary_cat":"physics.bio-ph","authors_text":"Allyson E. Sgro, David J. Schwab, Javad Noorbakhsh, Pankaj Mehta, Thomas Gregor, Troy Mestler","submitted_at":"2014-06-25T23:03:25Z","abstract_excerpt":"Collective behavior in cellular populations is coordinated by biochemical signaling networks within individual cells. Connecting the dynamics of these intracellular networks to the population phenomena they control poses a considerable challenge because of network complexity and our limited knowledge of kinetic parameters. However, from physical systems we know that behavioral changes in the individual constituents of a collectively-behaving system occur in a limited number of well-defined classes, and these can be described using simple models. Here we apply such an approach to the emergence "},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1406.6731","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T02:48:56Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"uosM+3Cx3MxXFAJnjRMEsaBt/e4Xnam+JIgSIjBisDgy6/RC1D0hTqHTU5eiOtIPZjEoFsL8WrYWLqfm1lOwAQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-01T00:36:01.636999Z"},"content_sha256":"438fd88a7605b8a94ec16f6a01e6eb631ccf4f8f54e7cca911d13f5a721670bb","schema_version":"1.0","event_id":"sha256:438fd88a7605b8a94ec16f6a01e6eb631ccf4f8f54e7cca911d13f5a721670bb"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/PIC7HQHLHU43OH5MFZ4EUOSD65/bundle.json","state_url":"https://pith.science/pith/PIC7HQHLHU43OH5MFZ4EUOSD65/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/PIC7HQHLHU43OH5MFZ4EUOSD65/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-06-01T00:36:01Z","links":{"resolver":"https://pith.science/pith/PIC7HQHLHU43OH5MFZ4EUOSD65","bundle":"https://pith.science/pith/PIC7HQHLHU43OH5MFZ4EUOSD65/bundle.json","state":"https://pith.science/pith/PIC7HQHLHU43OH5MFZ4EUOSD65/state.json","well_known_bundle":"https://pith.science/.well-known/pith/PIC7HQHLHU43OH5MFZ4EUOSD65/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2014:PIC7HQHLHU43OH5MFZ4EUOSD65","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"17db57995248e5ded9167cc98c61c756e63105ff2449dc7a6b57a1bd0cad5720","cross_cats_sorted":["q-bio.CB","q-bio.MN"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2014-06-25T23:03:25Z","title_canon_sha256":"26e68ac1f143d9b1646a8d7bcbbd7ebd2c88cfe2e84228dd3844ab9f4f995b6a"},"schema_version":"1.0","source":{"id":"1406.6731","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1406.6731","created_at":"2026-05-18T02:48:56Z"},{"alias_kind":"arxiv_version","alias_value":"1406.6731v1","created_at":"2026-05-18T02:48:56Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1406.6731","created_at":"2026-05-18T02:48:56Z"},{"alias_kind":"pith_short_12","alias_value":"PIC7HQHLHU43","created_at":"2026-05-18T12:28:43Z"},{"alias_kind":"pith_short_16","alias_value":"PIC7HQHLHU43OH5M","created_at":"2026-05-18T12:28:43Z"},{"alias_kind":"pith_short_8","alias_value":"PIC7HQHL","created_at":"2026-05-18T12:28:43Z"}],"graph_snapshots":[{"event_id":"sha256:438fd88a7605b8a94ec16f6a01e6eb631ccf4f8f54e7cca911d13f5a721670bb","target":"graph","created_at":"2026-05-18T02:48:56Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"Collective behavior in cellular populations is coordinated by biochemical signaling networks within individual cells. Connecting the dynamics of these intracellular networks to the population phenomena they control poses a considerable challenge because of network complexity and our limited knowledge of kinetic parameters. However, from physical systems we know that behavioral changes in the individual constituents of a collectively-behaving system occur in a limited number of well-defined classes, and these can be described using simple models. Here we apply such an approach to the emergence ","authors_text":"Allyson E. Sgro, David J. Schwab, Javad Noorbakhsh, Pankaj Mehta, Thomas Gregor, Troy Mestler","cross_cats":["q-bio.CB","q-bio.MN"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2014-06-25T23:03:25Z","title":"From Intracellular Signaling to Population Oscillations: Bridging Scales in Collective Behavior"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1406.6731","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:695928f5fabdecefd622c7c320712ba1cde1268daa789869ecdf3642783dc0f2","target":"record","created_at":"2026-05-18T02:48:56Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"17db57995248e5ded9167cc98c61c756e63105ff2449dc7a6b57a1bd0cad5720","cross_cats_sorted":["q-bio.CB","q-bio.MN"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2014-06-25T23:03:25Z","title_canon_sha256":"26e68ac1f143d9b1646a8d7bcbbd7ebd2c88cfe2e84228dd3844ab9f4f995b6a"},"schema_version":"1.0","source":{"id":"1406.6731","kind":"arxiv","version":1}},"canonical_sha256":"7a05f3c0eb3d39b71fac2e784a3a43f77b762fb13a1ea49731ab9abef253dcfb","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"7a05f3c0eb3d39b71fac2e784a3a43f77b762fb13a1ea49731ab9abef253dcfb","first_computed_at":"2026-05-18T02:48:56.031094Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T02:48:56.031094Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"KFyORc1MBSlFdk9BfGqF5PA+iECGoc/s3H5GmK+aZypfujAuFiy/M2YKmdUCDDqECHjNBYTZb5lgbWSfoVnCCg==","signature_status":"signed_v1","signed_at":"2026-05-18T02:48:56.031754Z","signed_message":"canonical_sha256_bytes"},"source_id":"1406.6731","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:695928f5fabdecefd622c7c320712ba1cde1268daa789869ecdf3642783dc0f2","sha256:438fd88a7605b8a94ec16f6a01e6eb631ccf4f8f54e7cca911d13f5a721670bb"],"state_sha256":"c1a24340c0e4bf3db35dd79f0559caf7fafef533c7f0148a58d74974d8d57dcf"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"KTI5R05Q+FkXFap6ejKteA/0m959c0NtYgevrfu/gvadLsajKQri7rCOvGN8kynVW1jixXq/bQ5SuKR+wbecDg==","signed_message":"bundle_sha256_bytes","signed_at":"2026-06-01T00:36:01.640359Z","bundle_sha256":"ec247570cfe809e891a31b91248ca17a0ffbc1e15b53752d2761e367babd1767"}}