{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2012:Q2XVQKTZVLOIGG2XFDSIJ6JLNN","short_pith_number":"pith:Q2XVQKTZ","canonical_record":{"source":{"id":"1204.3317","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.gen-ph","submitted_at":"2012-03-12T18:09:16Z","cross_cats_sorted":["physics.ins-det"],"title_canon_sha256":"e709a903e9e587686323226a4f75dac288851dbc9bf60e531a4a5d56341afba6","abstract_canon_sha256":"5a9525be6c87ff01547d566030175a3467d3a1887445449d3d4829c821fceb43"},"schema_version":"1.0"},"canonical_sha256":"86af582a79aadc831b5728e484f92b6b6d662d49f561816f409d426718381d3a","source":{"kind":"arxiv","id":"1204.3317","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1204.3317","created_at":"2026-05-18T01:57:52Z"},{"alias_kind":"arxiv_version","alias_value":"1204.3317v1","created_at":"2026-05-18T01:57:52Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1204.3317","created_at":"2026-05-18T01:57:52Z"},{"alias_kind":"pith_short_12","alias_value":"Q2XVQKTZVLOI","created_at":"2026-05-18T12:27:18Z"},{"alias_kind":"pith_short_16","alias_value":"Q2XVQKTZVLOIGG2X","created_at":"2026-05-18T12:27:18Z"},{"alias_kind":"pith_short_8","alias_value":"Q2XVQKTZ","created_at":"2026-05-18T12:27:18Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2012:Q2XVQKTZVLOIGG2XFDSIJ6JLNN","target":"record","payload":{"canonical_record":{"source":{"id":"1204.3317","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.gen-ph","submitted_at":"2012-03-12T18:09:16Z","cross_cats_sorted":["physics.ins-det"],"title_canon_sha256":"e709a903e9e587686323226a4f75dac288851dbc9bf60e531a4a5d56341afba6","abstract_canon_sha256":"5a9525be6c87ff01547d566030175a3467d3a1887445449d3d4829c821fceb43"},"schema_version":"1.0"},"canonical_sha256":"86af582a79aadc831b5728e484f92b6b6d662d49f561816f409d426718381d3a","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T01:57:52.366939Z","signature_b64":"z0UMJOYuSGVDmPWSiS/3ZF5gz4E0N+7PNSCb8nZuN97rZK8zTT9bty/hiBqMDgl41a6X72mOC0X/u9CwU8HcAA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"86af582a79aadc831b5728e484f92b6b6d662d49f561816f409d426718381d3a","last_reissued_at":"2026-05-18T01:57:52.366440Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T01:57:52.366440Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1204.3317","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T01:57:52Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"L1C5um3uFdH6JD/Xd7rugz5xcxONkTfP56lh3HX2tOUFi2gB7qDLVMx+SEL/Ibc1Scjva8oAyD3vvjBg8Qm4Bg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-09T03:50:49.228274Z"},"content_sha256":"b98452d436abc18dcf61bafecf69dbf7da423c97410f7ba93bc98d4091cf48d5","schema_version":"1.0","event_id":"sha256:b98452d436abc18dcf61bafecf69dbf7da423c97410f7ba93bc98d4091cf48d5"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2012:Q2XVQKTZVLOIGG2XFDSIJ6JLNN","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Optimum Drift Velocity for Single Molecule Fluorescence Bursts in Micro/Nano-Fluidic Channels","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["physics.ins-det"],"primary_cat":"physics.gen-ph","authors_text":"Claes G. Granqvist, Jun Kameoka, Laszlo B. Kish, Lazar L. Kish","submitted_at":"2012-03-12T18:09:16Z","abstract_excerpt":"Photonic burst histograms can be used to identify single protein molecules in micro/nano-fluidic channels provided the width of the histogram is narrow. Photonic shot noise and residence time fluctuations, caused by longitudinal diffusion, are the major sources of the histogram width. This Communication is a sequel to an earlier Letter of ours [L. L. Kish et al., Appl. Phys. Lett. 99, 143121 (2011)] and demonstrates that, for a given diffusion coefficient, an increase of the drift velocity enhances the relative shot noise and decreases the relative residence time fluctuations. This leads to an"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1204.3317","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T01:57:52Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"rzSk0LV9ghIsDOtEGXYNWbx1t01xojXsLn+POecs2R6xWmxqO8CUVocFNdZLtVGeORtbDVlE2R4cevWzKmwyAg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-09T03:50:49.228979Z"},"content_sha256":"9d8d82c813616d67a61c4e0bf17ed72168c0cf6c4d520dc09441145febd2aa61","schema_version":"1.0","event_id":"sha256:9d8d82c813616d67a61c4e0bf17ed72168c0cf6c4d520dc09441145febd2aa61"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/Q2XVQKTZVLOIGG2XFDSIJ6JLNN/bundle.json","state_url":"https://pith.science/pith/Q2XVQKTZVLOIGG2XFDSIJ6JLNN/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/Q2XVQKTZVLOIGG2XFDSIJ6JLNN/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-06-09T03:50:49Z","links":{"resolver":"https://pith.science/pith/Q2XVQKTZVLOIGG2XFDSIJ6JLNN","bundle":"https://pith.science/pith/Q2XVQKTZVLOIGG2XFDSIJ6JLNN/bundle.json","state":"https://pith.science/pith/Q2XVQKTZVLOIGG2XFDSIJ6JLNN/state.json","well_known_bundle":"https://pith.science/.well-known/pith/Q2XVQKTZVLOIGG2XFDSIJ6JLNN/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2012:Q2XVQKTZVLOIGG2XFDSIJ6JLNN","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"5a9525be6c87ff01547d566030175a3467d3a1887445449d3d4829c821fceb43","cross_cats_sorted":["physics.ins-det"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.gen-ph","submitted_at":"2012-03-12T18:09:16Z","title_canon_sha256":"e709a903e9e587686323226a4f75dac288851dbc9bf60e531a4a5d56341afba6"},"schema_version":"1.0","source":{"id":"1204.3317","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1204.3317","created_at":"2026-05-18T01:57:52Z"},{"alias_kind":"arxiv_version","alias_value":"1204.3317v1","created_at":"2026-05-18T01:57:52Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1204.3317","created_at":"2026-05-18T01:57:52Z"},{"alias_kind":"pith_short_12","alias_value":"Q2XVQKTZVLOI","created_at":"2026-05-18T12:27:18Z"},{"alias_kind":"pith_short_16","alias_value":"Q2XVQKTZVLOIGG2X","created_at":"2026-05-18T12:27:18Z"},{"alias_kind":"pith_short_8","alias_value":"Q2XVQKTZ","created_at":"2026-05-18T12:27:18Z"}],"graph_snapshots":[{"event_id":"sha256:9d8d82c813616d67a61c4e0bf17ed72168c0cf6c4d520dc09441145febd2aa61","target":"graph","created_at":"2026-05-18T01:57:52Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"Photonic burst histograms can be used to identify single protein molecules in micro/nano-fluidic channels provided the width of the histogram is narrow. Photonic shot noise and residence time fluctuations, caused by longitudinal diffusion, are the major sources of the histogram width. This Communication is a sequel to an earlier Letter of ours [L. L. Kish et al., Appl. Phys. Lett. 99, 143121 (2011)] and demonstrates that, for a given diffusion coefficient, an increase of the drift velocity enhances the relative shot noise and decreases the relative residence time fluctuations. This leads to an","authors_text":"Claes G. Granqvist, Jun Kameoka, Laszlo B. Kish, Lazar L. Kish","cross_cats":["physics.ins-det"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.gen-ph","submitted_at":"2012-03-12T18:09:16Z","title":"Optimum Drift Velocity for Single Molecule Fluorescence Bursts in Micro/Nano-Fluidic Channels"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1204.3317","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:b98452d436abc18dcf61bafecf69dbf7da423c97410f7ba93bc98d4091cf48d5","target":"record","created_at":"2026-05-18T01:57:52Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"5a9525be6c87ff01547d566030175a3467d3a1887445449d3d4829c821fceb43","cross_cats_sorted":["physics.ins-det"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.gen-ph","submitted_at":"2012-03-12T18:09:16Z","title_canon_sha256":"e709a903e9e587686323226a4f75dac288851dbc9bf60e531a4a5d56341afba6"},"schema_version":"1.0","source":{"id":"1204.3317","kind":"arxiv","version":1}},"canonical_sha256":"86af582a79aadc831b5728e484f92b6b6d662d49f561816f409d426718381d3a","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"86af582a79aadc831b5728e484f92b6b6d662d49f561816f409d426718381d3a","first_computed_at":"2026-05-18T01:57:52.366440Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T01:57:52.366440Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"z0UMJOYuSGVDmPWSiS/3ZF5gz4E0N+7PNSCb8nZuN97rZK8zTT9bty/hiBqMDgl41a6X72mOC0X/u9CwU8HcAA==","signature_status":"signed_v1","signed_at":"2026-05-18T01:57:52.366939Z","signed_message":"canonical_sha256_bytes"},"source_id":"1204.3317","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:b98452d436abc18dcf61bafecf69dbf7da423c97410f7ba93bc98d4091cf48d5","sha256:9d8d82c813616d67a61c4e0bf17ed72168c0cf6c4d520dc09441145febd2aa61"],"state_sha256":"0d818970c634f6621ea205591ddb46112abe9d59048a6a47ee2438e287f56c89"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"80qCSjVdbkxjaer/kl2L0UcrlLpOuEdyqoCtiMJAcgb0cTBL4wtdbrQnS062QGqywCS1n88kC2AjLa8PsftOCQ==","signed_message":"bundle_sha256_bytes","signed_at":"2026-06-09T03:50:49.232788Z","bundle_sha256":"2c6c4119d0cdec3c24465d7df5ab2395d1a06e8c0726ea6789446ceb68199ae9"}}