{"record_type":"pith_number_record","schema_url":"https://pith.science/schemas/pith-number/v1.json","pith_number":"pith:2016:Q5DWASJQWSSMOXCPVI5PTPAQZ7","short_pith_number":"pith:Q5DWASJQ","schema_version":"1.0","canonical_sha256":"8747604930b4a4c75c4faa3af9bc10cffe8cc7f09b0bee4b90024850bc6dce58","source":{"kind":"arxiv","id":"1601.08044","version":1},"attestation_state":"computed","paper":{"title":"Mechanism for the stabilization of protein clusters above the solubility curve","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["physics.bio-ph","physics.chem-ph"],"primary_cat":"cond-mat.soft","authors_text":"Gr\\'egoire Nicolis, James F. Lutsko","submitted_at":"2016-01-29T10:35:54Z","abstract_excerpt":"Pan, Vekilov and Lubchenko[\\textit{J. Phys. Chem. B}, 2010, \\textbf{114}, 7620] have proposed that dense stable protein clusters appearing in weak protein solutions above the solubility curve are composed of protein oligomers. The hypothesis is that a weak solution of oligomer species is unstable with respect to condensation causing the formation of dense, oligomer-rich droplets which are stabilized against growth by the monomer-oligomer reaction. Here, we show that such a combination of processes can be understood using a simple capillary model yielding analytic expressions for the cluster pr"},"verification_status":{"content_addressed":true,"pith_receipt":true,"author_attested":false,"weak_author_claims":0,"strong_author_claims":0,"externally_anchored":false,"storage_verified":false,"citation_signatures":0,"replication_records":0,"graph_snapshot":true,"references_resolved":false,"formal_links_present":false},"canonical_record":{"source":{"id":"1601.08044","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cond-mat.soft","submitted_at":"2016-01-29T10:35:54Z","cross_cats_sorted":["physics.bio-ph","physics.chem-ph"],"title_canon_sha256":"1935e525327775ffa4dad7cf30cd062b8191e3b77a464e26fa84bd3fbd3def0b","abstract_canon_sha256":"43938f3e44d766b2fa2ebf2d2cccc8ab914a176580b607d59841afdfb89f0b95"},"schema_version":"1.0"},"receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T01:21:41.098106Z","signature_b64":"NNMzRZJ3egVealcukTD2XDTHD1m3t3Rpf3kekt5w75IkqGoyZUZeqwIWO4ILXHgY8IkxNYb4YIHDZCx2T0qnCQ==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"8747604930b4a4c75c4faa3af9bc10cffe8cc7f09b0bee4b90024850bc6dce58","last_reissued_at":"2026-05-18T01:21:41.097611Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T01:21:41.097611Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"graph_snapshot":{"paper":{"title":"Mechanism for the stabilization of protein clusters above the solubility curve","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["physics.bio-ph","physics.chem-ph"],"primary_cat":"cond-mat.soft","authors_text":"Gr\\'egoire Nicolis, James F. Lutsko","submitted_at":"2016-01-29T10:35:54Z","abstract_excerpt":"Pan, Vekilov and Lubchenko[\\textit{J. Phys. Chem. B}, 2010, \\textbf{114}, 7620] have proposed that dense stable protein clusters appearing in weak protein solutions above the solubility curve are composed of protein oligomers. The hypothesis is that a weak solution of oligomer species is unstable with respect to condensation causing the formation of dense, oligomer-rich droplets which are stabilized against growth by the monomer-oligomer reaction. Here, we show that such a combination of processes can be understood using a simple capillary model yielding analytic expressions for the cluster pr"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1601.08044","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"aliases":[{"alias_kind":"arxiv","alias_value":"1601.08044","created_at":"2026-05-18T01:21:41.097696+00:00"},{"alias_kind":"arxiv_version","alias_value":"1601.08044v1","created_at":"2026-05-18T01:21:41.097696+00:00"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1601.08044","created_at":"2026-05-18T01:21:41.097696+00:00"},{"alias_kind":"pith_short_12","alias_value":"Q5DWASJQWSSM","created_at":"2026-05-18T12:30:39.010887+00:00"},{"alias_kind":"pith_short_16","alias_value":"Q5DWASJQWSSMOXCP","created_at":"2026-05-18T12:30:39.010887+00:00"},{"alias_kind":"pith_short_8","alias_value":"Q5DWASJQ","created_at":"2026-05-18T12:30:39.010887+00:00"}],"events":[],"event_summary":{},"paper_claims":[],"inbound_citations":{"count":0,"internal_anchor_count":0,"sample":[]},"formal_canon":{"evidence_count":0,"sample":[],"anchors":[]},"links":{"html":"https://pith.science/pith/Q5DWASJQWSSMOXCPVI5PTPAQZ7","json":"https://pith.science/pith/Q5DWASJQWSSMOXCPVI5PTPAQZ7.json","graph_json":"https://pith.science/api/pith-number/Q5DWASJQWSSMOXCPVI5PTPAQZ7/graph.json","events_json":"https://pith.science/api/pith-number/Q5DWASJQWSSMOXCPVI5PTPAQZ7/events.json","paper":"https://pith.science/paper/Q5DWASJQ"},"agent_actions":{"view_html":"https://pith.science/pith/Q5DWASJQWSSMOXCPVI5PTPAQZ7","download_json":"https://pith.science/pith/Q5DWASJQWSSMOXCPVI5PTPAQZ7.json","view_paper":"https://pith.science/paper/Q5DWASJQ","resolve_alias":"https://pith.science/api/pith-number/resolve?arxiv=1601.08044&json=true","fetch_graph":"https://pith.science/api/pith-number/Q5DWASJQWSSMOXCPVI5PTPAQZ7/graph.json","fetch_events":"https://pith.science/api/pith-number/Q5DWASJQWSSMOXCPVI5PTPAQZ7/events.json","actions":{"anchor_timestamp":"https://pith.science/pith/Q5DWASJQWSSMOXCPVI5PTPAQZ7/action/timestamp_anchor","attest_storage":"https://pith.science/pith/Q5DWASJQWSSMOXCPVI5PTPAQZ7/action/storage_attestation","attest_author":"https://pith.science/pith/Q5DWASJQWSSMOXCPVI5PTPAQZ7/action/author_attestation","sign_citation":"https://pith.science/pith/Q5DWASJQWSSMOXCPVI5PTPAQZ7/action/citation_signature","submit_replication":"https://pith.science/pith/Q5DWASJQWSSMOXCPVI5PTPAQZ7/action/replication_record"}},"created_at":"2026-05-18T01:21:41.097696+00:00","updated_at":"2026-05-18T01:21:41.097696+00:00"}