{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2017:QBEHZ5O67I4DYLITFLXGQ2VI2R","short_pith_number":"pith:QBEHZ5O6","canonical_record":{"source":{"id":"1705.03321","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2017-05-04T14:50:12Z","cross_cats_sorted":["cs.LG","q-bio.GN"],"title_canon_sha256":"6cd4dfe99e550b1cfb79c8c845734b97016918eaba5d228e063c61a553b790fb","abstract_canon_sha256":"abd11bc436f78dabdd6a7f9c5f6ca65a0ec4ee02515cec57cb2df907c00a626a"},"schema_version":"1.0"},"canonical_sha256":"80487cf5defa383c2d132aee686aa8d46379f46260395d008885aed257a39cf2","source":{"kind":"arxiv","id":"1705.03321","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1705.03321","created_at":"2026-05-18T00:44:48Z"},{"alias_kind":"arxiv_version","alias_value":"1705.03321v1","created_at":"2026-05-18T00:44:48Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1705.03321","created_at":"2026-05-18T00:44:48Z"},{"alias_kind":"pith_short_12","alias_value":"QBEHZ5O67I4D","created_at":"2026-05-18T12:31:37Z"},{"alias_kind":"pith_short_16","alias_value":"QBEHZ5O67I4DYLIT","created_at":"2026-05-18T12:31:37Z"},{"alias_kind":"pith_short_8","alias_value":"QBEHZ5O6","created_at":"2026-05-18T12:31:37Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2017:QBEHZ5O67I4DYLITFLXGQ2VI2R","target":"record","payload":{"canonical_record":{"source":{"id":"1705.03321","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2017-05-04T14:50:12Z","cross_cats_sorted":["cs.LG","q-bio.GN"],"title_canon_sha256":"6cd4dfe99e550b1cfb79c8c845734b97016918eaba5d228e063c61a553b790fb","abstract_canon_sha256":"abd11bc436f78dabdd6a7f9c5f6ca65a0ec4ee02515cec57cb2df907c00a626a"},"schema_version":"1.0"},"canonical_sha256":"80487cf5defa383c2d132aee686aa8d46379f46260395d008885aed257a39cf2","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T00:44:48.285947Z","signature_b64":"PwfOGpl1kNuDZFz0M61BWILjyWLhnvMXD292e7DbIH5DE0+/F//++eSMnf8LmosFOexdFTIjREgy3W+ajNLOCA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"80487cf5defa383c2d132aee686aa8d46379f46260395d008885aed257a39cf2","last_reissued_at":"2026-05-18T00:44:48.285240Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T00:44:48.285240Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1705.03321","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T00:44:48Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"e0PSvptyaNx4oMOFLn0YQyRMdweqe/ulG/Clsb9rLqK6YATR+xKHU5ECZlXtZQYy3ir2oTv2E+ijTF+mDIfkBw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-26T13:33:59.140195Z"},"content_sha256":"464d0161394f4d3e89afd24bbeb69cef3e42f30d7190018c8e302e3480279aee","schema_version":"1.0","event_id":"sha256:464d0161394f4d3e89afd24bbeb69cef3e42f30d7190018c8e302e3480279aee"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2017:QBEHZ5O67I4DYLITFLXGQ2VI2R","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"MotifMark: Finding Regulatory Motifs in DNA Sequences","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["cs.LG","q-bio.GN"],"primary_cat":"q-bio.QM","authors_text":"Charles L. Isbell, Hamid Reza Hassanzadeh, May D. Wang, Pushkar Kolhe","submitted_at":"2017-05-04T14:50:12Z","abstract_excerpt":"The interaction between proteins and DNA is a key driving force in a significant number of biological processes such as transcriptional regulation, repair, recombination, splicing, and DNA modification. The identification of DNA-binding sites and the specificity of target proteins in binding to these regions are two important steps in understanding the mechanisms of these biological activities. A number of high-throughput technologies have recently emerged that try to quantify the affinity between proteins and DNA motifs. Despite their success, these technologies have their own limitations and"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1705.03321","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T00:44:48Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"9chPWfEto/99Aed5aiRurGd6MShu1zAyjnq5f5YKx4AbtyJes98uA103cMPGifOfyMK11zTnb6vHjH5YjL3uAw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-26T13:33:59.140556Z"},"content_sha256":"9dd778df7d0ff5badc857f17a7a9bd835316a554d83810027a0075453eee0704","schema_version":"1.0","event_id":"sha256:9dd778df7d0ff5badc857f17a7a9bd835316a554d83810027a0075453eee0704"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/QBEHZ5O67I4DYLITFLXGQ2VI2R/bundle.json","state_url":"https://pith.science/pith/QBEHZ5O67I4DYLITFLXGQ2VI2R/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/QBEHZ5O67I4DYLITFLXGQ2VI2R/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-06-26T13:33:59Z","links":{"resolver":"https://pith.science/pith/QBEHZ5O67I4DYLITFLXGQ2VI2R","bundle":"https://pith.science/pith/QBEHZ5O67I4DYLITFLXGQ2VI2R/bundle.json","state":"https://pith.science/pith/QBEHZ5O67I4DYLITFLXGQ2VI2R/state.json","well_known_bundle":"https://pith.science/.well-known/pith/QBEHZ5O67I4DYLITFLXGQ2VI2R/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2017:QBEHZ5O67I4DYLITFLXGQ2VI2R","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"abd11bc436f78dabdd6a7f9c5f6ca65a0ec4ee02515cec57cb2df907c00a626a","cross_cats_sorted":["cs.LG","q-bio.GN"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2017-05-04T14:50:12Z","title_canon_sha256":"6cd4dfe99e550b1cfb79c8c845734b97016918eaba5d228e063c61a553b790fb"},"schema_version":"1.0","source":{"id":"1705.03321","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1705.03321","created_at":"2026-05-18T00:44:48Z"},{"alias_kind":"arxiv_version","alias_value":"1705.03321v1","created_at":"2026-05-18T00:44:48Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1705.03321","created_at":"2026-05-18T00:44:48Z"},{"alias_kind":"pith_short_12","alias_value":"QBEHZ5O67I4D","created_at":"2026-05-18T12:31:37Z"},{"alias_kind":"pith_short_16","alias_value":"QBEHZ5O67I4DYLIT","created_at":"2026-05-18T12:31:37Z"},{"alias_kind":"pith_short_8","alias_value":"QBEHZ5O6","created_at":"2026-05-18T12:31:37Z"}],"graph_snapshots":[{"event_id":"sha256:9dd778df7d0ff5badc857f17a7a9bd835316a554d83810027a0075453eee0704","target":"graph","created_at":"2026-05-18T00:44:48Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"The interaction between proteins and DNA is a key driving force in a significant number of biological processes such as transcriptional regulation, repair, recombination, splicing, and DNA modification. The identification of DNA-binding sites and the specificity of target proteins in binding to these regions are two important steps in understanding the mechanisms of these biological activities. A number of high-throughput technologies have recently emerged that try to quantify the affinity between proteins and DNA motifs. Despite their success, these technologies have their own limitations and","authors_text":"Charles L. Isbell, Hamid Reza Hassanzadeh, May D. Wang, Pushkar Kolhe","cross_cats":["cs.LG","q-bio.GN"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2017-05-04T14:50:12Z","title":"MotifMark: Finding Regulatory Motifs in DNA Sequences"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1705.03321","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:464d0161394f4d3e89afd24bbeb69cef3e42f30d7190018c8e302e3480279aee","target":"record","created_at":"2026-05-18T00:44:48Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"abd11bc436f78dabdd6a7f9c5f6ca65a0ec4ee02515cec57cb2df907c00a626a","cross_cats_sorted":["cs.LG","q-bio.GN"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2017-05-04T14:50:12Z","title_canon_sha256":"6cd4dfe99e550b1cfb79c8c845734b97016918eaba5d228e063c61a553b790fb"},"schema_version":"1.0","source":{"id":"1705.03321","kind":"arxiv","version":1}},"canonical_sha256":"80487cf5defa383c2d132aee686aa8d46379f46260395d008885aed257a39cf2","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"80487cf5defa383c2d132aee686aa8d46379f46260395d008885aed257a39cf2","first_computed_at":"2026-05-18T00:44:48.285240Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T00:44:48.285240Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"PwfOGpl1kNuDZFz0M61BWILjyWLhnvMXD292e7DbIH5DE0+/F//++eSMnf8LmosFOexdFTIjREgy3W+ajNLOCA==","signature_status":"signed_v1","signed_at":"2026-05-18T00:44:48.285947Z","signed_message":"canonical_sha256_bytes"},"source_id":"1705.03321","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:464d0161394f4d3e89afd24bbeb69cef3e42f30d7190018c8e302e3480279aee","sha256:9dd778df7d0ff5badc857f17a7a9bd835316a554d83810027a0075453eee0704"],"state_sha256":"29a88cd54daa9defc865e75f727e4d4733ed712299b056a0046a915ee3b7354a"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"HkIJKRI4NVvWaVNnpBze7Mn+2lFboyLlQucEjjai77UU9g1FtJAP9Iw8J8loRLHkh/xyqvS1iPodc52vKcvqAA==","signed_message":"bundle_sha256_bytes","signed_at":"2026-06-26T13:33:59.142534Z","bundle_sha256":"0db6d669bf0bf4a572a005d306df743824d60f52fe987ff8ed88934b66e53dc6"}}