{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2017:QDR774RYBK74S2N3YJ5LG4LFGV","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"af42721d000fbecfefcad4f0974fc148e6e412828efcc57c4dd2e40aedb0002e","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.chem-ph","submitted_at":"2017-06-09T18:03:44Z","title_canon_sha256":"686d7e3fcc10799b0117192860911512f0e9d5913e176c9b3b4fd74f3f2bf981"},"schema_version":"1.0","source":{"id":"1706.03080","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1706.03080","created_at":"2026-05-18T00:42:38Z"},{"alias_kind":"arxiv_version","alias_value":"1706.03080v1","created_at":"2026-05-18T00:42:38Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1706.03080","created_at":"2026-05-18T00:42:38Z"},{"alias_kind":"pith_short_12","alias_value":"QDR774RYBK74","created_at":"2026-05-18T12:31:37Z"},{"alias_kind":"pith_short_16","alias_value":"QDR774RYBK74S2N3","created_at":"2026-05-18T12:31:37Z"},{"alias_kind":"pith_short_8","alias_value":"QDR774RY","created_at":"2026-05-18T12:31:37Z"}],"graph_snapshots":[{"event_id":"sha256:3815311985c104696a3482663b711ea3acc0576ea849f22fbf5f8f33a6fcede3","target":"graph","created_at":"2026-05-18T00:42:38Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"Currently two factors hinder the use of collagen as building block of regenerative devices: the potential antigenicity, and limited mechanical strength in aqueous environment. Polymeric collagen is naturally found in the cross-linked state and is mechanically tougher than the monomeric, cross-link-free (acid-soluble) collagen ex vivo. The antigenicity of collagen, on the other hand, is mainly ascribed to inter-species variations in amino acid sequences, which are primarily located in the non-helical terminal telopeptides. Although these can be removed through enzymatic treatment to produce ate","authors_text":"David Wood, Giuseppe Tronci, Roison Holmes, Steve Kirk, Xeubin Yang","cross_cats":[],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.chem-ph","submitted_at":"2017-06-09T18:03:44Z","title":"Influence of telopeptides on the structural and physical properties of polymeric and monomeric acid-soluble type I collagen"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1706.03080","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:747f878ad01e3065bd01ead0a1f90590be22bf36d79de87a625656ea0329fb18","target":"record","created_at":"2026-05-18T00:42:38Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"af42721d000fbecfefcad4f0974fc148e6e412828efcc57c4dd2e40aedb0002e","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.chem-ph","submitted_at":"2017-06-09T18:03:44Z","title_canon_sha256":"686d7e3fcc10799b0117192860911512f0e9d5913e176c9b3b4fd74f3f2bf981"},"schema_version":"1.0","source":{"id":"1706.03080","kind":"arxiv","version":1}},"canonical_sha256":"80e3fff2380abfc969bbc27ab371653577df3448156b5ac7e5f0d420c21565f1","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"80e3fff2380abfc969bbc27ab371653577df3448156b5ac7e5f0d420c21565f1","first_computed_at":"2026-05-18T00:42:38.571362Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T00:42:38.571362Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"nWPN6KfswDccnNGM/JUxalyRxBJtVqwEVfAR/xMKglQPvuZIJTUoIyJkoc0WO9Gb1ENXTeKhO8bxVjP9vvCYAA==","signature_status":"signed_v1","signed_at":"2026-05-18T00:42:38.571993Z","signed_message":"canonical_sha256_bytes"},"source_id":"1706.03080","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:747f878ad01e3065bd01ead0a1f90590be22bf36d79de87a625656ea0329fb18","sha256:3815311985c104696a3482663b711ea3acc0576ea849f22fbf5f8f33a6fcede3"],"state_sha256":"ff14317b4a00ec59a25238944e287e786ee782aee61c4d4f7cc597c7bd9b82b6"}