{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2016:QETXT35W6WGCXPKD3XF6EJHY3I","short_pith_number":"pith:QETXT35W","canonical_record":{"source":{"id":"1605.06837","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"stat.ME","submitted_at":"2016-05-22T19:13:28Z","cross_cats_sorted":[],"title_canon_sha256":"4d916a1746329cf0535b413f8179d4ac3aa4999752197ba0e39dda646921da91","abstract_canon_sha256":"dc14d6555a932b1d497b7b9a194a696200004eca8b6ea2d58a774fe288beb9dc"},"schema_version":"1.0"},"canonical_sha256":"812779efb6f58c2bbd43ddcbe224f8da1dab6c612fcde9e89ce26285a9c6276f","source":{"kind":"arxiv","id":"1605.06837","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1605.06837","created_at":"2026-05-18T01:14:11Z"},{"alias_kind":"arxiv_version","alias_value":"1605.06837v1","created_at":"2026-05-18T01:14:11Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1605.06837","created_at":"2026-05-18T01:14:11Z"},{"alias_kind":"pith_short_12","alias_value":"QETXT35W6WGC","created_at":"2026-05-18T12:30:39Z"},{"alias_kind":"pith_short_16","alias_value":"QETXT35W6WGCXPKD","created_at":"2026-05-18T12:30:39Z"},{"alias_kind":"pith_short_8","alias_value":"QETXT35W","created_at":"2026-05-18T12:30:39Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2016:QETXT35W6WGCXPKD3XF6EJHY3I","target":"record","payload":{"canonical_record":{"source":{"id":"1605.06837","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"stat.ME","submitted_at":"2016-05-22T19:13:28Z","cross_cats_sorted":[],"title_canon_sha256":"4d916a1746329cf0535b413f8179d4ac3aa4999752197ba0e39dda646921da91","abstract_canon_sha256":"dc14d6555a932b1d497b7b9a194a696200004eca8b6ea2d58a774fe288beb9dc"},"schema_version":"1.0"},"canonical_sha256":"812779efb6f58c2bbd43ddcbe224f8da1dab6c612fcde9e89ce26285a9c6276f","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T01:14:11.117845Z","signature_b64":"rxHaMRXUqhPUP626zCjQwF+NXyD/tm+DKxM5OPSXGP304pjUDk90gDbNrKHKzDzTKRfVUItzh8QuX2+GZO9eDQ==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"812779efb6f58c2bbd43ddcbe224f8da1dab6c612fcde9e89ce26285a9c6276f","last_reissued_at":"2026-05-18T01:14:11.117069Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T01:14:11.117069Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1605.06837","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T01:14:11Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"QJ/RLUshwDhx6OuT7VdPR4wA8V/hpt9bfCm+xkCvgUQ0xyuJvZSTennUuXmWLKQV+glW7eOpzneu/d+9nWtACw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-22T23:27:42.739796Z"},"content_sha256":"0ca65517d3ff1d1381ddd438f744f2366225886bcada3840667e3b4602c39bc8","schema_version":"1.0","event_id":"sha256:0ca65517d3ff1d1381ddd438f744f2366225886bcada3840667e3b4602c39bc8"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2016:QETXT35W6WGCXPKD3XF6EJHY3I","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Functional Mapping of Multiple Dynamic Traits","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"stat.ME","authors_text":"Jiguo Cao, Junyi Gai, Liangliang Wang, Rongling Wu, Zhongwen Huang","submitted_at":"2016-05-22T19:13:28Z","abstract_excerpt":"Many biological phenomena undergo developmental changes in time and space. Functional mapping, which is aimed at mapping genes that affect developmental patterns, is instrumental for studying the genetic architecture of biological changes. Often biological processes are mediated by a network of developmental and physiological components and, therefore, are better described by multiple phenotypes. In this article, we develop a multivariate model for functional mapping that can detect and characterize quantitative trait loci (QTLs) that simultaneously control multiple dynamic traits. Because the"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1605.06837","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T01:14:11Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"kx+YVecJMw6jveyWPyUjRUFUzYLoIDRZqPCG5M8Wa4Zd+aVBSCnACe5UdpSG2J18Z2JjNvS5u71WXFbd1tmHCg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-22T23:27:42.740142Z"},"content_sha256":"09d4210f65e75e33b844da9aab92ee569fbccf3a0a79d080d2ba9a77ef87c7ee","schema_version":"1.0","event_id":"sha256:09d4210f65e75e33b844da9aab92ee569fbccf3a0a79d080d2ba9a77ef87c7ee"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/QETXT35W6WGCXPKD3XF6EJHY3I/bundle.json","state_url":"https://pith.science/pith/QETXT35W6WGCXPKD3XF6EJHY3I/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/QETXT35W6WGCXPKD3XF6EJHY3I/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-06-22T23:27:42Z","links":{"resolver":"https://pith.science/pith/QETXT35W6WGCXPKD3XF6EJHY3I","bundle":"https://pith.science/pith/QETXT35W6WGCXPKD3XF6EJHY3I/bundle.json","state":"https://pith.science/pith/QETXT35W6WGCXPKD3XF6EJHY3I/state.json","well_known_bundle":"https://pith.science/.well-known/pith/QETXT35W6WGCXPKD3XF6EJHY3I/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2016:QETXT35W6WGCXPKD3XF6EJHY3I","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"dc14d6555a932b1d497b7b9a194a696200004eca8b6ea2d58a774fe288beb9dc","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"stat.ME","submitted_at":"2016-05-22T19:13:28Z","title_canon_sha256":"4d916a1746329cf0535b413f8179d4ac3aa4999752197ba0e39dda646921da91"},"schema_version":"1.0","source":{"id":"1605.06837","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1605.06837","created_at":"2026-05-18T01:14:11Z"},{"alias_kind":"arxiv_version","alias_value":"1605.06837v1","created_at":"2026-05-18T01:14:11Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1605.06837","created_at":"2026-05-18T01:14:11Z"},{"alias_kind":"pith_short_12","alias_value":"QETXT35W6WGC","created_at":"2026-05-18T12:30:39Z"},{"alias_kind":"pith_short_16","alias_value":"QETXT35W6WGCXPKD","created_at":"2026-05-18T12:30:39Z"},{"alias_kind":"pith_short_8","alias_value":"QETXT35W","created_at":"2026-05-18T12:30:39Z"}],"graph_snapshots":[{"event_id":"sha256:09d4210f65e75e33b844da9aab92ee569fbccf3a0a79d080d2ba9a77ef87c7ee","target":"graph","created_at":"2026-05-18T01:14:11Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"Many biological phenomena undergo developmental changes in time and space. Functional mapping, which is aimed at mapping genes that affect developmental patterns, is instrumental for studying the genetic architecture of biological changes. Often biological processes are mediated by a network of developmental and physiological components and, therefore, are better described by multiple phenotypes. In this article, we develop a multivariate model for functional mapping that can detect and characterize quantitative trait loci (QTLs) that simultaneously control multiple dynamic traits. Because the","authors_text":"Jiguo Cao, Junyi Gai, Liangliang Wang, Rongling Wu, Zhongwen Huang","cross_cats":[],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"stat.ME","submitted_at":"2016-05-22T19:13:28Z","title":"Functional Mapping of Multiple Dynamic Traits"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1605.06837","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:0ca65517d3ff1d1381ddd438f744f2366225886bcada3840667e3b4602c39bc8","target":"record","created_at":"2026-05-18T01:14:11Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"dc14d6555a932b1d497b7b9a194a696200004eca8b6ea2d58a774fe288beb9dc","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"stat.ME","submitted_at":"2016-05-22T19:13:28Z","title_canon_sha256":"4d916a1746329cf0535b413f8179d4ac3aa4999752197ba0e39dda646921da91"},"schema_version":"1.0","source":{"id":"1605.06837","kind":"arxiv","version":1}},"canonical_sha256":"812779efb6f58c2bbd43ddcbe224f8da1dab6c612fcde9e89ce26285a9c6276f","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"812779efb6f58c2bbd43ddcbe224f8da1dab6c612fcde9e89ce26285a9c6276f","first_computed_at":"2026-05-18T01:14:11.117069Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T01:14:11.117069Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"rxHaMRXUqhPUP626zCjQwF+NXyD/tm+DKxM5OPSXGP304pjUDk90gDbNrKHKzDzTKRfVUItzh8QuX2+GZO9eDQ==","signature_status":"signed_v1","signed_at":"2026-05-18T01:14:11.117845Z","signed_message":"canonical_sha256_bytes"},"source_id":"1605.06837","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:0ca65517d3ff1d1381ddd438f744f2366225886bcada3840667e3b4602c39bc8","sha256:09d4210f65e75e33b844da9aab92ee569fbccf3a0a79d080d2ba9a77ef87c7ee"],"state_sha256":"313af6fce1ef9452394f7d3a37c03e2cb3c3c89e8a337cc8554bf93541afdb9e"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"rUhx8n/RiABZNF+PZQaYIsFswkZyNxUhoB9LWqLQzhyNUs/s3dowrBopRq75Ux9XuxLw+c18Is+mQUkFsmFvDw==","signed_message":"bundle_sha256_bytes","signed_at":"2026-06-22T23:27:42.742103Z","bundle_sha256":"2925d30de7fd8cb77ae5ae1570d572c732d426079a29e1e8d431e87dc718aca9"}}