{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2022:QHTGOSFLRU4IMFS7CHRHFQABZM","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"537865b64cd8eea9ca3e01038920ef5e3e4cfdbd661955afb73adcb21e9cd79c","cross_cats_sorted":["cs.LG","q-fin.TR"],"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"q-fin.ST","submitted_at":"2022-08-11T20:20:21Z","title_canon_sha256":"0274e61d9c720621071b03addcac8157d40185862b7bf4c1c1d2245c67c1ddfc"},"schema_version":"1.0","source":{"id":"2208.07248","kind":"arxiv","version":2}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2208.07248","created_at":"2026-07-05T04:49:03Z"},{"alias_kind":"arxiv_version","alias_value":"2208.07248v2","created_at":"2026-07-05T04:49:03Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2208.07248","created_at":"2026-07-05T04:49:03Z"},{"alias_kind":"pith_short_12","alias_value":"QHTGOSFLRU4I","created_at":"2026-07-05T04:49:03Z"},{"alias_kind":"pith_short_16","alias_value":"QHTGOSFLRU4IMFS7","created_at":"2026-07-05T04:49:03Z"},{"alias_kind":"pith_short_8","alias_value":"QHTGOSFL","created_at":"2026-07-05T04:49:03Z"}],"graph_snapshots":[{"event_id":"sha256:ed77981b78d84c44227065b09f058cc1bb1d20d150a89c4590f56cca01222cc8","target":"graph","created_at":"2026-07-05T04:49:03Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2208.07248/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"Pharmaceutical companies operate in a strictly regulated and highly risky environment in which a single slip can lead to serious financial implications. Accordingly, the announcements of clinical trial results tend to determine the future course of events, hence being closely monitored by the public. In this work, we provide statistical evidence for the result promulgation influence on the public pharma market value. Whereas most works focus on retrospective impact analysis, the present research aims to predict the numerical values of announcement-induced changes in stock prices. For this purp","authors_text":"Alexey Kazakov, Elizaveta Kovtun, Leonid Zhukov, Semen Budennyy","cross_cats":["cs.LG","q-fin.TR"],"headline":"","license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"q-fin.ST","submitted_at":"2022-08-11T20:20:21Z","title":"New drugs and stock market: how to predict pharma market reaction to clinical trial announcements"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2208.07248","kind":"arxiv","version":2},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:c46f049b68e8cc68932b18eaf0d8aea94212e1d5d7d2d27f72a8aeae10db3bd0","target":"record","created_at":"2026-07-05T04:49:03Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"537865b64cd8eea9ca3e01038920ef5e3e4cfdbd661955afb73adcb21e9cd79c","cross_cats_sorted":["cs.LG","q-fin.TR"],"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"q-fin.ST","submitted_at":"2022-08-11T20:20:21Z","title_canon_sha256":"0274e61d9c720621071b03addcac8157d40185862b7bf4c1c1d2245c67c1ddfc"},"schema_version":"1.0","source":{"id":"2208.07248","kind":"arxiv","version":2}},"canonical_sha256":"81e66748ab8d3886165f11e272c001cb070a929ac1ca4b02aafce874dad8cb78","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"81e66748ab8d3886165f11e272c001cb070a929ac1ca4b02aafce874dad8cb78","first_computed_at":"2026-07-05T04:49:03.977222Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-05T04:49:03.977222Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"F6H9nBRwKncRqe5XQKTyQJ5M7aqv4m05o5FIThll0AdIMCwvTrbrQ5p2WkCIfxQdDMe+hwvlJ23r5AvTSl2WDg==","signature_status":"signed_v1","signed_at":"2026-07-05T04:49:03.977660Z","signed_message":"canonical_sha256_bytes"},"source_id":"2208.07248","source_kind":"arxiv","source_version":2}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:c46f049b68e8cc68932b18eaf0d8aea94212e1d5d7d2d27f72a8aeae10db3bd0","sha256:ed77981b78d84c44227065b09f058cc1bb1d20d150a89c4590f56cca01222cc8"],"state_sha256":"faaab6ec4fc1a48b655baecb5a489a2d104e59d4501f1b3cccfb1f472247df87"}