{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2025:QSGOQTJIMFDAYXB5L5WNWUEYKD","short_pith_number":"pith:QSGOQTJI","canonical_record":{"source":{"id":"2506.13740","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"cs.CE","submitted_at":"2025-06-16T17:50:23Z","cross_cats_sorted":[],"title_canon_sha256":"be2c0133ff7cd11e86f06b967898c3aa6d08e1f634f22c94e4a1137e85466e39","abstract_canon_sha256":"5674c11741ab5db7c120e760e0b811c6693971ed02f26ba43fac5583e29fa89b"},"schema_version":"1.0"},"canonical_sha256":"848ce84d2861460c5c3d5f6cdb509850cd3e61e742df83ee5b81252e49efbdd3","source":{"kind":"arxiv","id":"2506.13740","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2506.13740","created_at":"2026-07-05T11:22:25Z"},{"alias_kind":"arxiv_version","alias_value":"2506.13740v1","created_at":"2026-07-05T11:22:25Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2506.13740","created_at":"2026-07-05T11:22:25Z"},{"alias_kind":"pith_short_12","alias_value":"QSGOQTJIMFDA","created_at":"2026-07-05T11:22:25Z"},{"alias_kind":"pith_short_16","alias_value":"QSGOQTJIMFDAYXB5","created_at":"2026-07-05T11:22:25Z"},{"alias_kind":"pith_short_8","alias_value":"QSGOQTJI","created_at":"2026-07-05T11:22:25Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2025:QSGOQTJIMFDAYXB5L5WNWUEYKD","target":"record","payload":{"canonical_record":{"source":{"id":"2506.13740","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"cs.CE","submitted_at":"2025-06-16T17:50:23Z","cross_cats_sorted":[],"title_canon_sha256":"be2c0133ff7cd11e86f06b967898c3aa6d08e1f634f22c94e4a1137e85466e39","abstract_canon_sha256":"5674c11741ab5db7c120e760e0b811c6693971ed02f26ba43fac5583e29fa89b"},"schema_version":"1.0"},"canonical_sha256":"848ce84d2861460c5c3d5f6cdb509850cd3e61e742df83ee5b81252e49efbdd3","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-07-05T11:22:25.750956Z","signature_b64":"85ZK9A44h+DYHWboyENIeDo7tG6KBfxadyfo/5rxpp7QnHNd8mv6VSKrnp8U/4eH02ZZZeiyHwTOwhaYWyv+Cw==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"848ce84d2861460c5c3d5f6cdb509850cd3e61e742df83ee5b81252e49efbdd3","last_reissued_at":"2026-07-05T11:22:25.750398Z","signature_status":"signed_v1","first_computed_at":"2026-07-05T11:22:25.750398Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"2506.13740","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T11:22:25Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"F2yYcQmUAeF6C/vG8uOj0FrD5YVxkuRpdQcN/qpGFuk9ZSgYdVU6FPiwiyYZvDGeBAWsRbWQwqhS/KykOJ5dCQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-08T21:34:18.784599Z"},"content_sha256":"7812b6ceb9de3c6c8a5f5c5a6b9120a855d88198bf9588c595cf68e05dd87e50","schema_version":"1.0","event_id":"sha256:7812b6ceb9de3c6c8a5f5c5a6b9120a855d88198bf9588c595cf68e05dd87e50"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2025:QSGOQTJIMFDAYXB5L5WNWUEYKD","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Kolmogorov-Arnold Network for Gene Regulatory Network Inference","license":"http://creativecommons.org/licenses/by/4.0/","headline":"","cross_cats":[],"primary_cat":"cs.CE","authors_text":"Aoran Wang, George Panagopoulos, Jun Pang, Tsz Pan Tong","submitted_at":"2025-06-16T17:50:23Z","abstract_excerpt":"Gene regulation is central to understanding cellular processes and development, potentially leading to the discovery of new treatments for diseases and personalized medicine. Inferring gene regulatory networks (GRNs) from single-cell RNA sequencing (scRNA-seq) data presents significant challenges due to its high dimensionality and complexity. Existing tree-based models, such as GENIE3 and GRNBOOST2, demonstrated scalability and explainability in GRN inference, but they cannot distinguish regulation types nor effectively capture continuous cellular dynamics. In this paper, we introduce scKAN, a"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2506.13740","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2506.13740/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T11:22:25Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"NRFu6njgijSKL29jN8pI59Z/1lVzX58Vf24ztMoUZrVuB1cbMbYqvck/7umCE61B7zHOWrGsU74JgWpJJBZuBg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-08T21:34:18.785111Z"},"content_sha256":"ad607475b68d04521a7d3e9c22615a8312fd12d63cc822816a77eeaa8a757772","schema_version":"1.0","event_id":"sha256:ad607475b68d04521a7d3e9c22615a8312fd12d63cc822816a77eeaa8a757772"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/QSGOQTJIMFDAYXB5L5WNWUEYKD/bundle.json","state_url":"https://pith.science/pith/QSGOQTJIMFDAYXB5L5WNWUEYKD/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/QSGOQTJIMFDAYXB5L5WNWUEYKD/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-08-08T21:34:18Z","links":{"resolver":"https://pith.science/pith/QSGOQTJIMFDAYXB5L5WNWUEYKD","bundle":"https://pith.science/pith/QSGOQTJIMFDAYXB5L5WNWUEYKD/bundle.json","state":"https://pith.science/pith/QSGOQTJIMFDAYXB5L5WNWUEYKD/state.json","well_known_bundle":"https://pith.science/.well-known/pith/QSGOQTJIMFDAYXB5L5WNWUEYKD/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2025:QSGOQTJIMFDAYXB5L5WNWUEYKD","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"5674c11741ab5db7c120e760e0b811c6693971ed02f26ba43fac5583e29fa89b","cross_cats_sorted":[],"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"cs.CE","submitted_at":"2025-06-16T17:50:23Z","title_canon_sha256":"be2c0133ff7cd11e86f06b967898c3aa6d08e1f634f22c94e4a1137e85466e39"},"schema_version":"1.0","source":{"id":"2506.13740","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2506.13740","created_at":"2026-07-05T11:22:25Z"},{"alias_kind":"arxiv_version","alias_value":"2506.13740v1","created_at":"2026-07-05T11:22:25Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2506.13740","created_at":"2026-07-05T11:22:25Z"},{"alias_kind":"pith_short_12","alias_value":"QSGOQTJIMFDA","created_at":"2026-07-05T11:22:25Z"},{"alias_kind":"pith_short_16","alias_value":"QSGOQTJIMFDAYXB5","created_at":"2026-07-05T11:22:25Z"},{"alias_kind":"pith_short_8","alias_value":"QSGOQTJI","created_at":"2026-07-05T11:22:25Z"}],"graph_snapshots":[{"event_id":"sha256:ad607475b68d04521a7d3e9c22615a8312fd12d63cc822816a77eeaa8a757772","target":"graph","created_at":"2026-07-05T11:22:25Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2506.13740/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"Gene regulation is central to understanding cellular processes and development, potentially leading to the discovery of new treatments for diseases and personalized medicine. Inferring gene regulatory networks (GRNs) from single-cell RNA sequencing (scRNA-seq) data presents significant challenges due to its high dimensionality and complexity. Existing tree-based models, such as GENIE3 and GRNBOOST2, demonstrated scalability and explainability in GRN inference, but they cannot distinguish regulation types nor effectively capture continuous cellular dynamics. In this paper, we introduce scKAN, a","authors_text":"Aoran Wang, George Panagopoulos, Jun Pang, Tsz Pan Tong","cross_cats":[],"headline":"","license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"cs.CE","submitted_at":"2025-06-16T17:50:23Z","title":"Kolmogorov-Arnold Network for Gene Regulatory Network Inference"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2506.13740","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:7812b6ceb9de3c6c8a5f5c5a6b9120a855d88198bf9588c595cf68e05dd87e50","target":"record","created_at":"2026-07-05T11:22:25Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"5674c11741ab5db7c120e760e0b811c6693971ed02f26ba43fac5583e29fa89b","cross_cats_sorted":[],"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"cs.CE","submitted_at":"2025-06-16T17:50:23Z","title_canon_sha256":"be2c0133ff7cd11e86f06b967898c3aa6d08e1f634f22c94e4a1137e85466e39"},"schema_version":"1.0","source":{"id":"2506.13740","kind":"arxiv","version":1}},"canonical_sha256":"848ce84d2861460c5c3d5f6cdb509850cd3e61e742df83ee5b81252e49efbdd3","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"848ce84d2861460c5c3d5f6cdb509850cd3e61e742df83ee5b81252e49efbdd3","first_computed_at":"2026-07-05T11:22:25.750398Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-05T11:22:25.750398Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"85ZK9A44h+DYHWboyENIeDo7tG6KBfxadyfo/5rxpp7QnHNd8mv6VSKrnp8U/4eH02ZZZeiyHwTOwhaYWyv+Cw==","signature_status":"signed_v1","signed_at":"2026-07-05T11:22:25.750956Z","signed_message":"canonical_sha256_bytes"},"source_id":"2506.13740","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:7812b6ceb9de3c6c8a5f5c5a6b9120a855d88198bf9588c595cf68e05dd87e50","sha256:ad607475b68d04521a7d3e9c22615a8312fd12d63cc822816a77eeaa8a757772"],"state_sha256":"7d852a54286983c5ee3967e08484aad47d004ad04764e4ddb94edc03c5d4f268"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"IomWZt+80dewJWiQfwdQOJJiwH1jE9aopXBkUGKIxTfUWuUI00djoD6YKLq+2EKiCfDMgP5KM+kncVhIFbYlBA==","signed_message":"bundle_sha256_bytes","signed_at":"2026-08-08T21:34:18.789328Z","bundle_sha256":"6d01afdb9cecd6d4972fe2c49b98a79159fb663bd250d4ab39dbb50164b0f2c4"}}