{"record_type":"pith_number_record","schema_url":"https://pith.science/schemas/pith-number/v1.json","pith_number":"pith:2015:QTQWO5XH4M4NHCOJQLKOZDNFRW","short_pith_number":"pith:QTQWO5XH","schema_version":"1.0","canonical_sha256":"84e16776e7e338d389c982d4ec8da58d9172fb68ab7a189cb034db0d29009e81","source":{"kind":"arxiv","id":"1504.03637","version":1},"attestation_state":"computed","paper":{"title":"Trade-offs in delayed information transmission in biochemical networks","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"q-bio.MN","authors_text":"Aleksandra M. Walczak, Francesca Mancini, Matteo Marsili","submitted_at":"2015-04-14T17:43:31Z","abstract_excerpt":"In order to transmit biochemical signals, biological regulatory systems dissipate energy with concomitant entropy production. Additionally, signaling often takes place in challenging environmental conditions. In a simple model regulatory circuit given by an input and a delayed output, we explore the trade-offs between information transmission and the system's energetic efficiency. We determine the maximally informative network, given a fixed amount of entropy production and delayed response, exploring both the case with and without feedback. We find that feedback allows the circuit to overcome"},"verification_status":{"content_addressed":true,"pith_receipt":true,"author_attested":false,"weak_author_claims":0,"strong_author_claims":0,"externally_anchored":false,"storage_verified":false,"citation_signatures":0,"replication_records":0,"graph_snapshot":true,"references_resolved":false,"formal_links_present":false},"canonical_record":{"source":{"id":"1504.03637","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.MN","submitted_at":"2015-04-14T17:43:31Z","cross_cats_sorted":[],"title_canon_sha256":"7ba62f0ffd84bb408daaa448507cfe2e703a5b397fafdf12904e28e5be61c96d","abstract_canon_sha256":"9a68fc923962145fb8bb840143f25a89b573ab37e585bc07ce61853097aa0e5e"},"schema_version":"1.0"},"receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T01:31:39.633864Z","signature_b64":"E4TLlxHe1/dBOhi+bYZxkvrWcZ1RSePhno2bIC5QQgvY+FcsI4lNBEo58ReDBVLODJHSvnQPRq14hehdnPi6DQ==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"84e16776e7e338d389c982d4ec8da58d9172fb68ab7a189cb034db0d29009e81","last_reissued_at":"2026-05-18T01:31:39.633405Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T01:31:39.633405Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"graph_snapshot":{"paper":{"title":"Trade-offs in delayed information transmission in biochemical networks","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"q-bio.MN","authors_text":"Aleksandra M. Walczak, Francesca Mancini, Matteo Marsili","submitted_at":"2015-04-14T17:43:31Z","abstract_excerpt":"In order to transmit biochemical signals, biological regulatory systems dissipate energy with concomitant entropy production. Additionally, signaling often takes place in challenging environmental conditions. In a simple model regulatory circuit given by an input and a delayed output, we explore the trade-offs between information transmission and the system's energetic efficiency. We determine the maximally informative network, given a fixed amount of entropy production and delayed response, exploring both the case with and without feedback. We find that feedback allows the circuit to overcome"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1504.03637","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"aliases":[{"alias_kind":"arxiv","alias_value":"1504.03637","created_at":"2026-05-18T01:31:39.633480+00:00"},{"alias_kind":"arxiv_version","alias_value":"1504.03637v1","created_at":"2026-05-18T01:31:39.633480+00:00"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1504.03637","created_at":"2026-05-18T01:31:39.633480+00:00"},{"alias_kind":"pith_short_12","alias_value":"QTQWO5XH4M4N","created_at":"2026-05-18T12:29:37.295048+00:00"},{"alias_kind":"pith_short_16","alias_value":"QTQWO5XH4M4NHCOJ","created_at":"2026-05-18T12:29:37.295048+00:00"},{"alias_kind":"pith_short_8","alias_value":"QTQWO5XH","created_at":"2026-05-18T12:29:37.295048+00:00"}],"events":[],"event_summary":{},"paper_claims":[],"inbound_citations":{"count":0,"internal_anchor_count":0,"sample":[]},"formal_canon":{"evidence_count":0,"sample":[],"anchors":[]},"links":{"html":"https://pith.science/pith/QTQWO5XH4M4NHCOJQLKOZDNFRW","json":"https://pith.science/pith/QTQWO5XH4M4NHCOJQLKOZDNFRW.json","graph_json":"https://pith.science/api/pith-number/QTQWO5XH4M4NHCOJQLKOZDNFRW/graph.json","events_json":"https://pith.science/api/pith-number/QTQWO5XH4M4NHCOJQLKOZDNFRW/events.json","paper":"https://pith.science/paper/QTQWO5XH"},"agent_actions":{"view_html":"https://pith.science/pith/QTQWO5XH4M4NHCOJQLKOZDNFRW","download_json":"https://pith.science/pith/QTQWO5XH4M4NHCOJQLKOZDNFRW.json","view_paper":"https://pith.science/paper/QTQWO5XH","resolve_alias":"https://pith.science/api/pith-number/resolve?arxiv=1504.03637&json=true","fetch_graph":"https://pith.science/api/pith-number/QTQWO5XH4M4NHCOJQLKOZDNFRW/graph.json","fetch_events":"https://pith.science/api/pith-number/QTQWO5XH4M4NHCOJQLKOZDNFRW/events.json","actions":{"anchor_timestamp":"https://pith.science/pith/QTQWO5XH4M4NHCOJQLKOZDNFRW/action/timestamp_anchor","attest_storage":"https://pith.science/pith/QTQWO5XH4M4NHCOJQLKOZDNFRW/action/storage_attestation","attest_author":"https://pith.science/pith/QTQWO5XH4M4NHCOJQLKOZDNFRW/action/author_attestation","sign_citation":"https://pith.science/pith/QTQWO5XH4M4NHCOJQLKOZDNFRW/action/citation_signature","submit_replication":"https://pith.science/pith/QTQWO5XH4M4NHCOJQLKOZDNFRW/action/replication_record"}},"created_at":"2026-05-18T01:31:39.633480+00:00","updated_at":"2026-05-18T01:31:39.633480+00:00"}