{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2013:QWRPKSEVGTAZOBHPKEJPYOO7XI","short_pith_number":"pith:QWRPKSEV","canonical_record":{"source":{"id":"1302.1641","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2013-02-07T04:40:52Z","cross_cats_sorted":["cond-mat.soft","q-bio.SC"],"title_canon_sha256":"e4716785778be506aa2ed44f84f29c0c2bb44707236a6a87b3db6699ffaa1180","abstract_canon_sha256":"227c3a46a77f8c3f633b1930426d6b715349e00c827dd0b2d8f8b94b9c01d977"},"schema_version":"1.0"},"canonical_sha256":"85a2f5489534c19704ef5112fc39dfba3c34add1d77aff1d335a815ba36f3012","source":{"kind":"arxiv","id":"1302.1641","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1302.1641","created_at":"2026-05-18T03:34:15Z"},{"alias_kind":"arxiv_version","alias_value":"1302.1641v1","created_at":"2026-05-18T03:34:15Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1302.1641","created_at":"2026-05-18T03:34:15Z"},{"alias_kind":"pith_short_12","alias_value":"QWRPKSEVGTAZ","created_at":"2026-05-18T12:27:57Z"},{"alias_kind":"pith_short_16","alias_value":"QWRPKSEVGTAZOBHP","created_at":"2026-05-18T12:27:57Z"},{"alias_kind":"pith_short_8","alias_value":"QWRPKSEV","created_at":"2026-05-18T12:27:57Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2013:QWRPKSEVGTAZOBHPKEJPYOO7XI","target":"record","payload":{"canonical_record":{"source":{"id":"1302.1641","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2013-02-07T04:40:52Z","cross_cats_sorted":["cond-mat.soft","q-bio.SC"],"title_canon_sha256":"e4716785778be506aa2ed44f84f29c0c2bb44707236a6a87b3db6699ffaa1180","abstract_canon_sha256":"227c3a46a77f8c3f633b1930426d6b715349e00c827dd0b2d8f8b94b9c01d977"},"schema_version":"1.0"},"canonical_sha256":"85a2f5489534c19704ef5112fc39dfba3c34add1d77aff1d335a815ba36f3012","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T03:34:15.213258Z","signature_b64":"EXOqNj8zJSCjVB30mZCzSvE/FvtdiB7r/e+QVAAHmSgKusOTRaWAwgN2QHJPn4H7ZMZGDhQsK4KJolnFVhggDw==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"85a2f5489534c19704ef5112fc39dfba3c34add1d77aff1d335a815ba36f3012","last_reissued_at":"2026-05-18T03:34:15.212511Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T03:34:15.212511Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1302.1641","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T03:34:15Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"E8sURZlztzeYvZ6XkvR5eRPGBCYDrO7GBRuGySBvMrIhfAlO54+mMJCwLn0DwYfvp4FxrJlgES1TL6fy3vT4AQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-31T15:23:25.953787Z"},"content_sha256":"6ca6f28f95eca1aece87efd2c85da5070e7a331116334ad5d508d3ea5c512a00","schema_version":"1.0","event_id":"sha256:6ca6f28f95eca1aece87efd2c85da5070e7a331116334ad5d508d3ea5c512a00"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2013:QWRPKSEVGTAZOBHPKEJPYOO7XI","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Membrane mediated aggregation of curvature inducing nematogens and membrane tubulation","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["cond-mat.soft","q-bio.SC"],"primary_cat":"physics.bio-ph","authors_text":"John H. Ipsen, N. Ramakrishnan, P. B. Sunil Kumar","submitted_at":"2013-02-07T04:40:52Z","abstract_excerpt":"The shapes of cell membranes are largely regulated by membrane associated, curvature active, proteins. We use a numerical model of the membrane with elongated membrane inclusions, recently developed by us, which posses spontaneous directional curvatures that could be different along and perpendicular to its long axis. We show that, due to membrane mediated interactions these curvature inducing membrane nematogens can oligomerize spontaneously, even at low concentrations, and change the local shape of the membrane. We demonstrate that for a large group of such inclusions, where the two spontane"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1302.1641","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T03:34:15Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"P1xB5py1CHYE+dOEJcdSQykmBdokGELhXu9sOOF7BhQqLtYSCOFDVwBYZFFpCoyPJdOi+I7/JAbPqCyRTPuTCA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-31T15:23:25.954345Z"},"content_sha256":"0b9684acd6fd657f0e0a5e7100c8467c1779f5f21d689efc3520240421cbf461","schema_version":"1.0","event_id":"sha256:0b9684acd6fd657f0e0a5e7100c8467c1779f5f21d689efc3520240421cbf461"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/QWRPKSEVGTAZOBHPKEJPYOO7XI/bundle.json","state_url":"https://pith.science/pith/QWRPKSEVGTAZOBHPKEJPYOO7XI/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/QWRPKSEVGTAZOBHPKEJPYOO7XI/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-05-31T15:23:25Z","links":{"resolver":"https://pith.science/pith/QWRPKSEVGTAZOBHPKEJPYOO7XI","bundle":"https://pith.science/pith/QWRPKSEVGTAZOBHPKEJPYOO7XI/bundle.json","state":"https://pith.science/pith/QWRPKSEVGTAZOBHPKEJPYOO7XI/state.json","well_known_bundle":"https://pith.science/.well-known/pith/QWRPKSEVGTAZOBHPKEJPYOO7XI/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2013:QWRPKSEVGTAZOBHPKEJPYOO7XI","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"227c3a46a77f8c3f633b1930426d6b715349e00c827dd0b2d8f8b94b9c01d977","cross_cats_sorted":["cond-mat.soft","q-bio.SC"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2013-02-07T04:40:52Z","title_canon_sha256":"e4716785778be506aa2ed44f84f29c0c2bb44707236a6a87b3db6699ffaa1180"},"schema_version":"1.0","source":{"id":"1302.1641","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1302.1641","created_at":"2026-05-18T03:34:15Z"},{"alias_kind":"arxiv_version","alias_value":"1302.1641v1","created_at":"2026-05-18T03:34:15Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1302.1641","created_at":"2026-05-18T03:34:15Z"},{"alias_kind":"pith_short_12","alias_value":"QWRPKSEVGTAZ","created_at":"2026-05-18T12:27:57Z"},{"alias_kind":"pith_short_16","alias_value":"QWRPKSEVGTAZOBHP","created_at":"2026-05-18T12:27:57Z"},{"alias_kind":"pith_short_8","alias_value":"QWRPKSEV","created_at":"2026-05-18T12:27:57Z"}],"graph_snapshots":[{"event_id":"sha256:0b9684acd6fd657f0e0a5e7100c8467c1779f5f21d689efc3520240421cbf461","target":"graph","created_at":"2026-05-18T03:34:15Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"The shapes of cell membranes are largely regulated by membrane associated, curvature active, proteins. We use a numerical model of the membrane with elongated membrane inclusions, recently developed by us, which posses spontaneous directional curvatures that could be different along and perpendicular to its long axis. We show that, due to membrane mediated interactions these curvature inducing membrane nematogens can oligomerize spontaneously, even at low concentrations, and change the local shape of the membrane. We demonstrate that for a large group of such inclusions, where the two spontane","authors_text":"John H. Ipsen, N. Ramakrishnan, P. B. Sunil Kumar","cross_cats":["cond-mat.soft","q-bio.SC"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2013-02-07T04:40:52Z","title":"Membrane mediated aggregation of curvature inducing nematogens and membrane tubulation"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1302.1641","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:6ca6f28f95eca1aece87efd2c85da5070e7a331116334ad5d508d3ea5c512a00","target":"record","created_at":"2026-05-18T03:34:15Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"227c3a46a77f8c3f633b1930426d6b715349e00c827dd0b2d8f8b94b9c01d977","cross_cats_sorted":["cond-mat.soft","q-bio.SC"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2013-02-07T04:40:52Z","title_canon_sha256":"e4716785778be506aa2ed44f84f29c0c2bb44707236a6a87b3db6699ffaa1180"},"schema_version":"1.0","source":{"id":"1302.1641","kind":"arxiv","version":1}},"canonical_sha256":"85a2f5489534c19704ef5112fc39dfba3c34add1d77aff1d335a815ba36f3012","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"85a2f5489534c19704ef5112fc39dfba3c34add1d77aff1d335a815ba36f3012","first_computed_at":"2026-05-18T03:34:15.212511Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T03:34:15.212511Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"EXOqNj8zJSCjVB30mZCzSvE/FvtdiB7r/e+QVAAHmSgKusOTRaWAwgN2QHJPn4H7ZMZGDhQsK4KJolnFVhggDw==","signature_status":"signed_v1","signed_at":"2026-05-18T03:34:15.213258Z","signed_message":"canonical_sha256_bytes"},"source_id":"1302.1641","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:6ca6f28f95eca1aece87efd2c85da5070e7a331116334ad5d508d3ea5c512a00","sha256:0b9684acd6fd657f0e0a5e7100c8467c1779f5f21d689efc3520240421cbf461"],"state_sha256":"7cc4ea45c38b560c736e1bbc6e714663642882a29c379bda0c9e703d3db26efc"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"l7URq0E4htrthECvbJMlWhl+UGJtp7qYzLzbnbdzWHvmNXEZO3uULbtIFm9TXMYIDM2ZrA81uCZsgshiEvpyCA==","signed_message":"bundle_sha256_bytes","signed_at":"2026-05-31T15:23:25.958287Z","bundle_sha256":"33434ee0df8d24cde007651ad293070f1a45018902aee440eb6d125f417b4440"}}