{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2013:RAKQNX5ACBUW7E3FNU6MWUW5MT","short_pith_number":"pith:RAKQNX5A","canonical_record":{"source":{"id":"1310.5601","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2013-10-21T15:30:26Z","cross_cats_sorted":[],"title_canon_sha256":"60f9bba5c5d69db09d2ac928cd3ddb2e0ba96759b832cc63c0f4001e26609e96","abstract_canon_sha256":"06143a7f4de265ef9458899c227930863c35ad3470c5025679aa2f3b7ad1cdf2"},"schema_version":"1.0"},"canonical_sha256":"881506dfa010696f93656d3ccb52dd64e761816e595a5f4ec2187b29dc19f0f9","source":{"kind":"arxiv","id":"1310.5601","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1310.5601","created_at":"2026-05-18T01:46:56Z"},{"alias_kind":"arxiv_version","alias_value":"1310.5601v1","created_at":"2026-05-18T01:46:56Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1310.5601","created_at":"2026-05-18T01:46:56Z"},{"alias_kind":"pith_short_12","alias_value":"RAKQNX5ACBUW","created_at":"2026-05-18T12:27:57Z"},{"alias_kind":"pith_short_16","alias_value":"RAKQNX5ACBUW7E3F","created_at":"2026-05-18T12:27:57Z"},{"alias_kind":"pith_short_8","alias_value":"RAKQNX5A","created_at":"2026-05-18T12:27:57Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2013:RAKQNX5ACBUW7E3FNU6MWUW5MT","target":"record","payload":{"canonical_record":{"source":{"id":"1310.5601","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2013-10-21T15:30:26Z","cross_cats_sorted":[],"title_canon_sha256":"60f9bba5c5d69db09d2ac928cd3ddb2e0ba96759b832cc63c0f4001e26609e96","abstract_canon_sha256":"06143a7f4de265ef9458899c227930863c35ad3470c5025679aa2f3b7ad1cdf2"},"schema_version":"1.0"},"canonical_sha256":"881506dfa010696f93656d3ccb52dd64e761816e595a5f4ec2187b29dc19f0f9","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T01:46:56.878396Z","signature_b64":"oTy6OzliWtsXsMnfkH1tlkwqQah54dVm3G0MHoqMCFR3ZcOp4sYSrtin8inPJI251MJLsLyQwzGE6Mo8SIZxAw==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"881506dfa010696f93656d3ccb52dd64e761816e595a5f4ec2187b29dc19f0f9","last_reissued_at":"2026-05-18T01:46:56.877852Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T01:46:56.877852Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1310.5601","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T01:46:56Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"C+21xYISMjmiI7yHh7xFI+uKtBHl3cpnwTxq9XMioptMAhSMO3QPbgloBvzZlrbwPgxZVt6CUwPjQcg6hVXHCg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-23T08:02:49.609443Z"},"content_sha256":"8677e3ab340b08ef09f699b3cf22eec33f5b8c0a22704e8c56664e14f7185888","schema_version":"1.0","event_id":"sha256:8677e3ab340b08ef09f699b3cf22eec33f5b8c0a22704e8c56664e14f7185888"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2013:RAKQNX5ACBUW7E3FNU6MWUW5MT","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Neuronal Growth as Diffusion in an Effective Potential","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"physics.bio-ph","authors_text":"Cristian Staii, Daniel J. Rizzo, David L. Kaplan, Elise Spedden, James D. White, Matthew R. Wiens, Timothy J. Atherton","submitted_at":"2013-10-21T15:30:26Z","abstract_excerpt":"Current understanding of neuronal growth is mostly qualitative, as the staggering number of physical and chemical guidance cues involved prohibit a fully quantitative description of axonal dynamics. We report on a general approach that describes axonal growth in vitro, on poly-D-lysine coated glass substrates, as diffusion in an effective external potential, representing the collective contribution of all causal influences on the growth cone. We use this approach to obtain effective growth rules that reveal an emergent regulatory mechanism for axonal pathfinding on these substrates."},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1310.5601","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T01:46:56Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"znoaZSAaSmZH3Y8p1KFAVeM4ruSUtlbwg2Agxc4TTkFRbSdDhTQlX2e+YhckmR9SdD3oqjBogySwWqay1d8IAw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-23T08:02:49.609983Z"},"content_sha256":"f7e1eb23f2a321d41e8a30f442cb0754553a1664f1adb5890709ef9a325dd868","schema_version":"1.0","event_id":"sha256:f7e1eb23f2a321d41e8a30f442cb0754553a1664f1adb5890709ef9a325dd868"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/RAKQNX5ACBUW7E3FNU6MWUW5MT/bundle.json","state_url":"https://pith.science/pith/RAKQNX5ACBUW7E3FNU6MWUW5MT/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/RAKQNX5ACBUW7E3FNU6MWUW5MT/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-06-23T08:02:49Z","links":{"resolver":"https://pith.science/pith/RAKQNX5ACBUW7E3FNU6MWUW5MT","bundle":"https://pith.science/pith/RAKQNX5ACBUW7E3FNU6MWUW5MT/bundle.json","state":"https://pith.science/pith/RAKQNX5ACBUW7E3FNU6MWUW5MT/state.json","well_known_bundle":"https://pith.science/.well-known/pith/RAKQNX5ACBUW7E3FNU6MWUW5MT/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2013:RAKQNX5ACBUW7E3FNU6MWUW5MT","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"06143a7f4de265ef9458899c227930863c35ad3470c5025679aa2f3b7ad1cdf2","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2013-10-21T15:30:26Z","title_canon_sha256":"60f9bba5c5d69db09d2ac928cd3ddb2e0ba96759b832cc63c0f4001e26609e96"},"schema_version":"1.0","source":{"id":"1310.5601","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1310.5601","created_at":"2026-05-18T01:46:56Z"},{"alias_kind":"arxiv_version","alias_value":"1310.5601v1","created_at":"2026-05-18T01:46:56Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1310.5601","created_at":"2026-05-18T01:46:56Z"},{"alias_kind":"pith_short_12","alias_value":"RAKQNX5ACBUW","created_at":"2026-05-18T12:27:57Z"},{"alias_kind":"pith_short_16","alias_value":"RAKQNX5ACBUW7E3F","created_at":"2026-05-18T12:27:57Z"},{"alias_kind":"pith_short_8","alias_value":"RAKQNX5A","created_at":"2026-05-18T12:27:57Z"}],"graph_snapshots":[{"event_id":"sha256:f7e1eb23f2a321d41e8a30f442cb0754553a1664f1adb5890709ef9a325dd868","target":"graph","created_at":"2026-05-18T01:46:56Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"Current understanding of neuronal growth is mostly qualitative, as the staggering number of physical and chemical guidance cues involved prohibit a fully quantitative description of axonal dynamics. We report on a general approach that describes axonal growth in vitro, on poly-D-lysine coated glass substrates, as diffusion in an effective external potential, representing the collective contribution of all causal influences on the growth cone. We use this approach to obtain effective growth rules that reveal an emergent regulatory mechanism for axonal pathfinding on these substrates.","authors_text":"Cristian Staii, Daniel J. Rizzo, David L. Kaplan, Elise Spedden, James D. White, Matthew R. Wiens, Timothy J. Atherton","cross_cats":[],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2013-10-21T15:30:26Z","title":"Neuronal Growth as Diffusion in an Effective Potential"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1310.5601","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:8677e3ab340b08ef09f699b3cf22eec33f5b8c0a22704e8c56664e14f7185888","target":"record","created_at":"2026-05-18T01:46:56Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"06143a7f4de265ef9458899c227930863c35ad3470c5025679aa2f3b7ad1cdf2","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2013-10-21T15:30:26Z","title_canon_sha256":"60f9bba5c5d69db09d2ac928cd3ddb2e0ba96759b832cc63c0f4001e26609e96"},"schema_version":"1.0","source":{"id":"1310.5601","kind":"arxiv","version":1}},"canonical_sha256":"881506dfa010696f93656d3ccb52dd64e761816e595a5f4ec2187b29dc19f0f9","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"881506dfa010696f93656d3ccb52dd64e761816e595a5f4ec2187b29dc19f0f9","first_computed_at":"2026-05-18T01:46:56.877852Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T01:46:56.877852Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"oTy6OzliWtsXsMnfkH1tlkwqQah54dVm3G0MHoqMCFR3ZcOp4sYSrtin8inPJI251MJLsLyQwzGE6Mo8SIZxAw==","signature_status":"signed_v1","signed_at":"2026-05-18T01:46:56.878396Z","signed_message":"canonical_sha256_bytes"},"source_id":"1310.5601","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:8677e3ab340b08ef09f699b3cf22eec33f5b8c0a22704e8c56664e14f7185888","sha256:f7e1eb23f2a321d41e8a30f442cb0754553a1664f1adb5890709ef9a325dd868"],"state_sha256":"4366d72e58572b18ccf6974a4d5a1ce149728ea2d6744d00c7dee65f48ce34c1"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"tGJScu7S9mginQRmUJx6ON2X1XI/Z7ycWLK8sxLPqt0jaZf38Qy4WpuewQ59118m5VOlqrY6PV8oCtId8fdjCA==","signed_message":"bundle_sha256_bytes","signed_at":"2026-06-23T08:02:49.611921Z","bundle_sha256":"dd85c87addec5fbe214776beb26a1cf11f20395c72ffe2f8f8beb17b95bc9ca7"}}