{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2009:RULSKW32HSPEJKXJ6LWRVXMK3O","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"5caedb9bb70faa053b279bba3d8140a364b09ea1a96771bd05dd345328a7073f","cross_cats_sorted":["q-bio.SC"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.BM","submitted_at":"2009-09-02T16:14:59Z","title_canon_sha256":"94b047d7a06507f2b9b8122a98e134975adc634fe831c716c0cf4a7afb12b4b7"},"schema_version":"1.0","source":{"id":"0909.0466","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"0909.0466","created_at":"2026-05-18T03:48:02Z"},{"alias_kind":"arxiv_version","alias_value":"0909.0466v1","created_at":"2026-05-18T03:48:02Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.0909.0466","created_at":"2026-05-18T03:48:02Z"},{"alias_kind":"pith_short_12","alias_value":"RULSKW32HSPE","created_at":"2026-05-18T12:26:01Z"},{"alias_kind":"pith_short_16","alias_value":"RULSKW32HSPEJKXJ","created_at":"2026-05-18T12:26:01Z"},{"alias_kind":"pith_short_8","alias_value":"RULSKW32","created_at":"2026-05-18T12:26:01Z"}],"graph_snapshots":[{"event_id":"sha256:dd3eeda49241b7184702c2b44cd163de75da2559d43a4359cf416616bec916b2","target":"graph","created_at":"2026-05-18T03:48:02Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"Determining the mechanism by which transfer RNAs (tRNAs) rapidly and precisely transit through the ribosomal A, P and E sites during translation remains a major goal in the study of protein synthesis. Here, we report the real-time dynamics of the L1 stalk, a structural element of the large ribosomal subunit that is implicated in directing tRNA movements during translation. Within pre-translocation ribosomal complexes, the L1 stalk exists in a dynamic equilibrium between open and closed conformations. Binding of elongation factor G (EF-G) shifts this equilibrium towards the closed conformation ","authors_text":"Chris H. Wiggins, Jake M. Hofman, Jingyi Fei, Jonathan E. Bronson, jr, Rathi L. Srinivas, Ruben L. Gonzalez","cross_cats":["q-bio.SC"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.BM","submitted_at":"2009-09-02T16:14:59Z","title":"Allosteric collaboration between elongation factor G and the ribosomal L1 stalk directs tRNA movements during translation"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"0909.0466","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:f0c0e706f28f077e93aa3aa2eda3cc567d1eb9c30dd0b3e2ae5185775380511f","target":"record","created_at":"2026-05-18T03:48:02Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"5caedb9bb70faa053b279bba3d8140a364b09ea1a96771bd05dd345328a7073f","cross_cats_sorted":["q-bio.SC"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.BM","submitted_at":"2009-09-02T16:14:59Z","title_canon_sha256":"94b047d7a06507f2b9b8122a98e134975adc634fe831c716c0cf4a7afb12b4b7"},"schema_version":"1.0","source":{"id":"0909.0466","kind":"arxiv","version":1}},"canonical_sha256":"8d17255b7a3c9e44aae9f2ed1add8adbbb61ebcdc205d495e51972438e3d5de8","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"8d17255b7a3c9e44aae9f2ed1add8adbbb61ebcdc205d495e51972438e3d5de8","first_computed_at":"2026-05-18T03:48:02.314822Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T03:48:02.314822Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"V2Burb39nWJQeL4lKGq5oV8Ks7kbptiXfApmd4CY32dSdrre8jWOu98JdQuNxbXnLDQE0CXtGfmFCWvb9u1ICQ==","signature_status":"signed_v1","signed_at":"2026-05-18T03:48:02.315426Z","signed_message":"canonical_sha256_bytes"},"source_id":"0909.0466","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:f0c0e706f28f077e93aa3aa2eda3cc567d1eb9c30dd0b3e2ae5185775380511f","sha256:dd3eeda49241b7184702c2b44cd163de75da2559d43a4359cf416616bec916b2"],"state_sha256":"b27a86b6418fa030c29887d18d8d347e2a77234dcf2d58ed69feac4fa55934d8"}