{"record_type":"pith_number_record","schema_url":"https://pith.science/schemas/pith-number/v1.json","pith_number":"pith:2023:SHQVUDJQC3SHZEQ2EKVDH2U3E4","short_pith_number":"pith:SHQVUDJQ","schema_version":"1.0","canonical_sha256":"91e15a0d3016e47c921a22aa33ea9b2728637c312cd8865a181f7a9342d04622","source":{"kind":"arxiv","id":"2302.09299","version":1},"attestation_state":"computed","paper":{"title":"LIGHT-SABRE hyperpolarizes 1-^{13}C-pyruvate continuously, without magnetic field cycling","license":"http://creativecommons.org/licenses/by-nc-sa/4.0/","headline":"","cross_cats":[],"primary_cat":"physics.chem-ph","authors_text":"Andrey N. Pravdivtsev, Gabrielle Stevanato, Jan-Bernd H\\\"ovener, Joern Engelmann, Kai Buckenmaier, Klaus Scheffler, Markus Plaumann, Nicolas Kempf, Rainer Koerber, Thomas Theis","submitted_at":"2023-02-18T11:34:23Z","abstract_excerpt":"Nuclear spin hyperpolarization enables real-time observation of metabolism and intermolecular interactions in vivo. 1-13C-Pyruvate is the leading hyperpolarized tracer currently under evaluation in several clinical trials as a promising molecular imaging agent. Still, the quest for a simple, fast, and efficient hyperpolarization technique is ongoing. Here, we describe that continuous, weak irradiation in the audio-frequency range of the 13C spin at 121 {\\mu}T magnetic field (\\sim twiceEarth\\apos s field) enables spin order transfer from parahydrogen to 13C magnetization of 1-13C-pyruvate. Thes"},"verification_status":{"content_addressed":true,"pith_receipt":true,"author_attested":false,"weak_author_claims":0,"strong_author_claims":0,"externally_anchored":false,"storage_verified":false,"citation_signatures":0,"replication_records":0,"graph_snapshot":true,"references_resolved":false,"formal_links_present":false},"canonical_record":{"source":{"id":"2302.09299","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/licenses/by-nc-sa/4.0/","primary_cat":"physics.chem-ph","submitted_at":"2023-02-18T11:34:23Z","cross_cats_sorted":[],"title_canon_sha256":"4c2a7f79573fe7c510a62c09b17f61407a74fee47e2f9a976765b73a7101464e","abstract_canon_sha256":"4392067b2d12cea203550566185ee9a4d44f49b844e57a49ef64d15c741260c5"},"schema_version":"1.0"},"receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-07-05T09:50:42.995074Z","signature_b64":"3lZVQTbPuACqNXfEPy/E8frWlar+R89OiX10wtO4JvS+ZIOdIzfrLnglRaHjbw7iR3x/ggwWIiyS357cuyykCw==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"91e15a0d3016e47c921a22aa33ea9b2728637c312cd8865a181f7a9342d04622","last_reissued_at":"2026-07-05T09:50:42.994679Z","signature_status":"signed_v1","first_computed_at":"2026-07-05T09:50:42.994679Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"graph_snapshot":{"paper":{"title":"LIGHT-SABRE hyperpolarizes 1-^{13}C-pyruvate continuously, without magnetic field cycling","license":"http://creativecommons.org/licenses/by-nc-sa/4.0/","headline":"","cross_cats":[],"primary_cat":"physics.chem-ph","authors_text":"Andrey N. Pravdivtsev, Gabrielle Stevanato, Jan-Bernd H\\\"ovener, Joern Engelmann, Kai Buckenmaier, Klaus Scheffler, Markus Plaumann, Nicolas Kempf, Rainer Koerber, Thomas Theis","submitted_at":"2023-02-18T11:34:23Z","abstract_excerpt":"Nuclear spin hyperpolarization enables real-time observation of metabolism and intermolecular interactions in vivo. 1-13C-Pyruvate is the leading hyperpolarized tracer currently under evaluation in several clinical trials as a promising molecular imaging agent. Still, the quest for a simple, fast, and efficient hyperpolarization technique is ongoing. Here, we describe that continuous, weak irradiation in the audio-frequency range of the 13C spin at 121 {\\mu}T magnetic field (\\sim twiceEarth\\apos s field) enables spin order transfer from parahydrogen to 13C magnetization of 1-13C-pyruvate. Thes"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2302.09299","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2302.09299/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"aliases":[{"alias_kind":"arxiv","alias_value":"2302.09299","created_at":"2026-07-05T09:50:42.994734+00:00"},{"alias_kind":"arxiv_version","alias_value":"2302.09299v1","created_at":"2026-07-05T09:50:42.994734+00:00"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2302.09299","created_at":"2026-07-05T09:50:42.994734+00:00"},{"alias_kind":"pith_short_12","alias_value":"SHQVUDJQC3SH","created_at":"2026-07-05T09:50:42.994734+00:00"},{"alias_kind":"pith_short_16","alias_value":"SHQVUDJQC3SHZEQ2","created_at":"2026-07-05T09:50:42.994734+00:00"},{"alias_kind":"pith_short_8","alias_value":"SHQVUDJQ","created_at":"2026-07-05T09:50:42.994734+00:00"}],"events":[],"event_summary":{},"paper_claims":[],"inbound_citations":{"count":0,"internal_anchor_count":0,"sample":[]},"formal_canon":{"evidence_count":0,"sample":[],"anchors":[]},"links":{"html":"https://pith.science/pith/SHQVUDJQC3SHZEQ2EKVDH2U3E4","json":"https://pith.science/pith/SHQVUDJQC3SHZEQ2EKVDH2U3E4.json","graph_json":"https://pith.science/api/pith-number/SHQVUDJQC3SHZEQ2EKVDH2U3E4/graph.json","events_json":"https://pith.science/api/pith-number/SHQVUDJQC3SHZEQ2EKVDH2U3E4/events.json","paper":"https://pith.science/paper/SHQVUDJQ"},"agent_actions":{"view_html":"https://pith.science/pith/SHQVUDJQC3SHZEQ2EKVDH2U3E4","download_json":"https://pith.science/pith/SHQVUDJQC3SHZEQ2EKVDH2U3E4.json","view_paper":"https://pith.science/paper/SHQVUDJQ","resolve_alias":"https://pith.science/api/pith-number/resolve?arxiv=2302.09299&json=true","fetch_graph":"https://pith.science/api/pith-number/SHQVUDJQC3SHZEQ2EKVDH2U3E4/graph.json","fetch_events":"https://pith.science/api/pith-number/SHQVUDJQC3SHZEQ2EKVDH2U3E4/events.json","actions":{"anchor_timestamp":"https://pith.science/pith/SHQVUDJQC3SHZEQ2EKVDH2U3E4/action/timestamp_anchor","attest_storage":"https://pith.science/pith/SHQVUDJQC3SHZEQ2EKVDH2U3E4/action/storage_attestation","attest_author":"https://pith.science/pith/SHQVUDJQC3SHZEQ2EKVDH2U3E4/action/author_attestation","sign_citation":"https://pith.science/pith/SHQVUDJQC3SHZEQ2EKVDH2U3E4/action/citation_signature","submit_replication":"https://pith.science/pith/SHQVUDJQC3SHZEQ2EKVDH2U3E4/action/replication_record"}},"created_at":"2026-07-05T09:50:42.994734+00:00","updated_at":"2026-07-05T09:50:42.994734+00:00"}