{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2021:SMWLYLFTBKEAZ77A6XEF2LP2KY","short_pith_number":"pith:SMWLYLFT","canonical_record":{"source":{"id":"2111.10443","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"physics.med-ph","submitted_at":"2021-11-19T21:30:42Z","cross_cats_sorted":["cs.CV"],"title_canon_sha256":"23dac810a6316807a1de0fd27909b37b42627a88e80ad834f7db3bb17024b465","abstract_canon_sha256":"e4f55a464036dbfb754e764a036ddde75199c610972f3cce3650644b52e5805b"},"schema_version":"1.0"},"canonical_sha256":"932cbc2cb30a880cffe0f5c85d2dfa5623730bf93d4a6d6f2387c0725d81d0bd","source":{"kind":"arxiv","id":"2111.10443","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2111.10443","created_at":"2026-07-05T03:33:52Z"},{"alias_kind":"arxiv_version","alias_value":"2111.10443v1","created_at":"2026-07-05T03:33:52Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2111.10443","created_at":"2026-07-05T03:33:52Z"},{"alias_kind":"pith_short_12","alias_value":"SMWLYLFTBKEA","created_at":"2026-07-05T03:33:52Z"},{"alias_kind":"pith_short_16","alias_value":"SMWLYLFTBKEAZ77A","created_at":"2026-07-05T03:33:52Z"},{"alias_kind":"pith_short_8","alias_value":"SMWLYLFT","created_at":"2026-07-05T03:33:52Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2021:SMWLYLFTBKEAZ77A6XEF2LP2KY","target":"record","payload":{"canonical_record":{"source":{"id":"2111.10443","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"physics.med-ph","submitted_at":"2021-11-19T21:30:42Z","cross_cats_sorted":["cs.CV"],"title_canon_sha256":"23dac810a6316807a1de0fd27909b37b42627a88e80ad834f7db3bb17024b465","abstract_canon_sha256":"e4f55a464036dbfb754e764a036ddde75199c610972f3cce3650644b52e5805b"},"schema_version":"1.0"},"canonical_sha256":"932cbc2cb30a880cffe0f5c85d2dfa5623730bf93d4a6d6f2387c0725d81d0bd","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-07-05T03:33:52.857521Z","signature_b64":"Q4hJgYwndsHpdHCVEjks5qkJVnDUHSCDvCfb0P4kB+1LfCY8X6TOLGubhA6xMjXVhzthScZuVo6BEPnImQ0YCA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"932cbc2cb30a880cffe0f5c85d2dfa5623730bf93d4a6d6f2387c0725d81d0bd","last_reissued_at":"2026-07-05T03:33:52.857037Z","signature_status":"signed_v1","first_computed_at":"2026-07-05T03:33:52.857037Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"2111.10443","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T03:33:52Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"vMNzLHF35glQHQwCG5b7W4iC4xr2X3PeQTMYyd7/hmeW9o6ccLMBZU+/jHhFO/9uQGAfpM7XxY+G02fV9GFUDQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-05T11:49:03.193001Z"},"content_sha256":"44c221bde58bce9ab9c1b8ebd380382989f05387ad234a5fc9a3782a7f4712e4","schema_version":"1.0","event_id":"sha256:44c221bde58bce9ab9c1b8ebd380382989f05387ad234a5fc9a3782a7f4712e4"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2021:SMWLYLFTBKEAZ77A6XEF2LP2KY","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Evaluation of automated airway morphological quantification for assessing fibrosing lung disease","license":"http://creativecommons.org/licenses/by/4.0/","headline":"","cross_cats":["cs.CV"],"primary_cat":"physics.med-ph","authors_text":"Alper Ezircan, Ashkan Pakzad, Brian J. Bartholmai, Carole Sudre, Cassandra Braun, Coline H.M. Van Moorsel, Daniel C. Alexander, David Hawkes, Finbar Foley, Frouke Van Beek, Hendrik W. Van Es, John R Hurst, Joseph Jacob, Kin Quan, Marcel Veltkamp, Nesrin Mogulkoc, Peter Wijeratne, Recep Savas, Ronald Karwoski, Ryan D. Clay, Tobias Peikert, Tom Doel, Wing Keung Cheung, Yipeng Hu","submitted_at":"2021-11-19T21:30:42Z","abstract_excerpt":"Abnormal airway dilatation, termed traction bronchiectasis, is a typical feature of idiopathic pulmonary fibrosis (IPF). Volumetric computed tomography (CT) imaging captures the loss of normal airway tapering in IPF. We postulated that automated quantification of airway abnormalities could provide estimates of IPF disease extent and severity. We propose AirQuant, an automated computational pipeline that systematically parcellates the airway tree into its lobes and generational branches from a deep learning based airway segmentation, deriving airway structural measures from chest CT. Importantl"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2111.10443","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2111.10443/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T03:33:52Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"rdhZU691HrLoghHA88kXnvT36mQ7Fq/XAUZ3Yg57KATFEsccG7EKr5bXl95rtJDpN6G/HC79HAuXUTtm4C28Ag==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-05T11:49:03.194037Z"},"content_sha256":"12d5bb6425b73a2a5dd5c51cb923f2f225b3a67f220fbbbd6f955f09958b8c1b","schema_version":"1.0","event_id":"sha256:12d5bb6425b73a2a5dd5c51cb923f2f225b3a67f220fbbbd6f955f09958b8c1b"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/SMWLYLFTBKEAZ77A6XEF2LP2KY/bundle.json","state_url":"https://pith.science/pith/SMWLYLFTBKEAZ77A6XEF2LP2KY/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/SMWLYLFTBKEAZ77A6XEF2LP2KY/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-08-05T11:49:03Z","links":{"resolver":"https://pith.science/pith/SMWLYLFTBKEAZ77A6XEF2LP2KY","bundle":"https://pith.science/pith/SMWLYLFTBKEAZ77A6XEF2LP2KY/bundle.json","state":"https://pith.science/pith/SMWLYLFTBKEAZ77A6XEF2LP2KY/state.json","well_known_bundle":"https://pith.science/.well-known/pith/SMWLYLFTBKEAZ77A6XEF2LP2KY/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2021:SMWLYLFTBKEAZ77A6XEF2LP2KY","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"e4f55a464036dbfb754e764a036ddde75199c610972f3cce3650644b52e5805b","cross_cats_sorted":["cs.CV"],"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"physics.med-ph","submitted_at":"2021-11-19T21:30:42Z","title_canon_sha256":"23dac810a6316807a1de0fd27909b37b42627a88e80ad834f7db3bb17024b465"},"schema_version":"1.0","source":{"id":"2111.10443","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2111.10443","created_at":"2026-07-05T03:33:52Z"},{"alias_kind":"arxiv_version","alias_value":"2111.10443v1","created_at":"2026-07-05T03:33:52Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2111.10443","created_at":"2026-07-05T03:33:52Z"},{"alias_kind":"pith_short_12","alias_value":"SMWLYLFTBKEA","created_at":"2026-07-05T03:33:52Z"},{"alias_kind":"pith_short_16","alias_value":"SMWLYLFTBKEAZ77A","created_at":"2026-07-05T03:33:52Z"},{"alias_kind":"pith_short_8","alias_value":"SMWLYLFT","created_at":"2026-07-05T03:33:52Z"}],"graph_snapshots":[{"event_id":"sha256:12d5bb6425b73a2a5dd5c51cb923f2f225b3a67f220fbbbd6f955f09958b8c1b","target":"graph","created_at":"2026-07-05T03:33:52Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2111.10443/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"Abnormal airway dilatation, termed traction bronchiectasis, is a typical feature of idiopathic pulmonary fibrosis (IPF). Volumetric computed tomography (CT) imaging captures the loss of normal airway tapering in IPF. We postulated that automated quantification of airway abnormalities could provide estimates of IPF disease extent and severity. We propose AirQuant, an automated computational pipeline that systematically parcellates the airway tree into its lobes and generational branches from a deep learning based airway segmentation, deriving airway structural measures from chest CT. Importantl","authors_text":"Alper Ezircan, Ashkan Pakzad, Brian J. Bartholmai, Carole Sudre, Cassandra Braun, Coline H.M. Van Moorsel, Daniel C. Alexander, David Hawkes, Finbar Foley, Frouke Van Beek, Hendrik W. Van Es, John R Hurst, Joseph Jacob, Kin Quan, Marcel Veltkamp, Nesrin Mogulkoc, Peter Wijeratne, Recep Savas, Ronald Karwoski, Ryan D. Clay, Tobias Peikert, Tom Doel, Wing Keung Cheung, Yipeng Hu","cross_cats":["cs.CV"],"headline":"","license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"physics.med-ph","submitted_at":"2021-11-19T21:30:42Z","title":"Evaluation of automated airway morphological quantification for assessing fibrosing lung disease"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2111.10443","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:44c221bde58bce9ab9c1b8ebd380382989f05387ad234a5fc9a3782a7f4712e4","target":"record","created_at":"2026-07-05T03:33:52Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"e4f55a464036dbfb754e764a036ddde75199c610972f3cce3650644b52e5805b","cross_cats_sorted":["cs.CV"],"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"physics.med-ph","submitted_at":"2021-11-19T21:30:42Z","title_canon_sha256":"23dac810a6316807a1de0fd27909b37b42627a88e80ad834f7db3bb17024b465"},"schema_version":"1.0","source":{"id":"2111.10443","kind":"arxiv","version":1}},"canonical_sha256":"932cbc2cb30a880cffe0f5c85d2dfa5623730bf93d4a6d6f2387c0725d81d0bd","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"932cbc2cb30a880cffe0f5c85d2dfa5623730bf93d4a6d6f2387c0725d81d0bd","first_computed_at":"2026-07-05T03:33:52.857037Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-05T03:33:52.857037Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"Q4hJgYwndsHpdHCVEjks5qkJVnDUHSCDvCfb0P4kB+1LfCY8X6TOLGubhA6xMjXVhzthScZuVo6BEPnImQ0YCA==","signature_status":"signed_v1","signed_at":"2026-07-05T03:33:52.857521Z","signed_message":"canonical_sha256_bytes"},"source_id":"2111.10443","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:44c221bde58bce9ab9c1b8ebd380382989f05387ad234a5fc9a3782a7f4712e4","sha256:12d5bb6425b73a2a5dd5c51cb923f2f225b3a67f220fbbbd6f955f09958b8c1b"],"state_sha256":"81fa9cb98646e14b3b588f9bc5b838b5283dedf60124098a6f516aa4846496af"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"0gySTP5GEibVAJip4Nx/todPsVkhFPxCIJftb5IC4xblA4VYhTQHKSmQVoHLy9B6yQAyi+Y015Ri5uvcHgKRBw==","signed_message":"bundle_sha256_bytes","signed_at":"2026-08-05T11:49:03.199260Z","bundle_sha256":"0661b8792b068496b64233fe3bf927641e30c881f886b6d9328c747393aaea5b"}}