{"record_type":"pith_number_record","schema_url":"https://pith.science/schemas/pith-number/v1.json","pith_number":"pith:2018:T4NWVLLSJKRMMOMNQ2VOLHXXHN","short_pith_number":"pith:T4NWVLLS","schema_version":"1.0","canonical_sha256":"9f1b6aad724aa2c6398d86aae59ef73b706be5c7f5b1a6fc7994e23cacb56e5a","source":{"kind":"arxiv","id":"1812.07455","version":1},"attestation_state":"computed","paper":{"title":"Wavelet Screaming: a novel approach to analyzing GWAS data","license":"http://creativecommons.org/licenses/by-nc-sa/4.0/","headline":"","cross_cats":[],"primary_cat":"stat.AP","authors_text":"Astanand Jugessur, Bo Jacobsson, H\\r{a}kon K. Gjessing, Julius Juodakis, William Denault","submitted_at":"2018-10-17T18:18:07Z","abstract_excerpt":"We present an alternative method for genome-wide association studies (GWAS) that is more powerful than the regular GWAS method for locus detection. The regular GWAS method suffers from a substantial multiple-testing burden because of the millions of single nucleotide polymorphisms (SNPs) being tested simultaneously. Furthermore, it does not consider the functional genetic effect on the response variable; i.e., it ignores more complex joint effects of nearby SNPs within a region. Our proposed method screens the entire genome for associations using a sequential sliding-window approach based on w"},"verification_status":{"content_addressed":true,"pith_receipt":true,"author_attested":false,"weak_author_claims":0,"strong_author_claims":0,"externally_anchored":false,"storage_verified":false,"citation_signatures":0,"replication_records":0,"graph_snapshot":true,"references_resolved":false,"formal_links_present":false},"canonical_record":{"source":{"id":"1812.07455","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/licenses/by-nc-sa/4.0/","primary_cat":"stat.AP","submitted_at":"2018-10-17T18:18:07Z","cross_cats_sorted":[],"title_canon_sha256":"c26af6c5c398084d85d1bca474a60fbfb9295aa2eeebcbf70872e5bfef67d351","abstract_canon_sha256":"8fc536384f97bdbc9eb3007e84bea1440d06f9252c464139b589d455360f9457"},"schema_version":"1.0"},"receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-17T23:58:00.460978Z","signature_b64":"gkrQAKZm+oXTw/fKzWVroyrXgcL4VKb8641kfVn1cB3truOshE/KiGjr94JhmjU13mV/GiFTOLv4MgEjDUaLDA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"9f1b6aad724aa2c6398d86aae59ef73b706be5c7f5b1a6fc7994e23cacb56e5a","last_reissued_at":"2026-05-17T23:58:00.460395Z","signature_status":"signed_v1","first_computed_at":"2026-05-17T23:58:00.460395Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"graph_snapshot":{"paper":{"title":"Wavelet Screaming: a novel approach to analyzing GWAS data","license":"http://creativecommons.org/licenses/by-nc-sa/4.0/","headline":"","cross_cats":[],"primary_cat":"stat.AP","authors_text":"Astanand Jugessur, Bo Jacobsson, H\\r{a}kon K. Gjessing, Julius Juodakis, William Denault","submitted_at":"2018-10-17T18:18:07Z","abstract_excerpt":"We present an alternative method for genome-wide association studies (GWAS) that is more powerful than the regular GWAS method for locus detection. The regular GWAS method suffers from a substantial multiple-testing burden because of the millions of single nucleotide polymorphisms (SNPs) being tested simultaneously. Furthermore, it does not consider the functional genetic effect on the response variable; i.e., it ignores more complex joint effects of nearby SNPs within a region. Our proposed method screens the entire genome for associations using a sequential sliding-window approach based on w"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1812.07455","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"aliases":[{"alias_kind":"arxiv","alias_value":"1812.07455","created_at":"2026-05-17T23:58:00.460502+00:00"},{"alias_kind":"arxiv_version","alias_value":"1812.07455v1","created_at":"2026-05-17T23:58:00.460502+00:00"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1812.07455","created_at":"2026-05-17T23:58:00.460502+00:00"},{"alias_kind":"pith_short_12","alias_value":"T4NWVLLSJKRM","created_at":"2026-05-18T12:32:53.628368+00:00"},{"alias_kind":"pith_short_16","alias_value":"T4NWVLLSJKRMMOMN","created_at":"2026-05-18T12:32:53.628368+00:00"},{"alias_kind":"pith_short_8","alias_value":"T4NWVLLS","created_at":"2026-05-18T12:32:53.628368+00:00"}],"events":[],"event_summary":{},"paper_claims":[],"inbound_citations":{"count":0,"internal_anchor_count":0,"sample":[]},"formal_canon":{"evidence_count":0,"sample":[],"anchors":[]},"links":{"html":"https://pith.science/pith/T4NWVLLSJKRMMOMNQ2VOLHXXHN","json":"https://pith.science/pith/T4NWVLLSJKRMMOMNQ2VOLHXXHN.json","graph_json":"https://pith.science/api/pith-number/T4NWVLLSJKRMMOMNQ2VOLHXXHN/graph.json","events_json":"https://pith.science/api/pith-number/T4NWVLLSJKRMMOMNQ2VOLHXXHN/events.json","paper":"https://pith.science/paper/T4NWVLLS"},"agent_actions":{"view_html":"https://pith.science/pith/T4NWVLLSJKRMMOMNQ2VOLHXXHN","download_json":"https://pith.science/pith/T4NWVLLSJKRMMOMNQ2VOLHXXHN.json","view_paper":"https://pith.science/paper/T4NWVLLS","resolve_alias":"https://pith.science/api/pith-number/resolve?arxiv=1812.07455&json=true","fetch_graph":"https://pith.science/api/pith-number/T4NWVLLSJKRMMOMNQ2VOLHXXHN/graph.json","fetch_events":"https://pith.science/api/pith-number/T4NWVLLSJKRMMOMNQ2VOLHXXHN/events.json","actions":{"anchor_timestamp":"https://pith.science/pith/T4NWVLLSJKRMMOMNQ2VOLHXXHN/action/timestamp_anchor","attest_storage":"https://pith.science/pith/T4NWVLLSJKRMMOMNQ2VOLHXXHN/action/storage_attestation","attest_author":"https://pith.science/pith/T4NWVLLSJKRMMOMNQ2VOLHXXHN/action/author_attestation","sign_citation":"https://pith.science/pith/T4NWVLLSJKRMMOMNQ2VOLHXXHN/action/citation_signature","submit_replication":"https://pith.science/pith/T4NWVLLSJKRMMOMNQ2VOLHXXHN/action/replication_record"}},"created_at":"2026-05-17T23:58:00.460502+00:00","updated_at":"2026-05-17T23:58:00.460502+00:00"}