{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2017:T5FDY6BIABYNIMUE7Z33JFUP6M","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"76c4fd9453c95448c0bb21b5998af94f1aed0bd6e65fd8d2845b3ed8780bfc55","cross_cats_sorted":["cond-mat.dis-nn","physics.bio-ph"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.MN","submitted_at":"2017-03-02T12:15:14Z","title_canon_sha256":"f2265b5d8380b38b0944dbe205bdaf72383585489b93f6ddfe1a0954c656e583"},"schema_version":"1.0","source":{"id":"1703.00748","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1703.00748","created_at":"2026-05-18T00:49:40Z"},{"alias_kind":"arxiv_version","alias_value":"1703.00748v1","created_at":"2026-05-18T00:49:40Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1703.00748","created_at":"2026-05-18T00:49:40Z"},{"alias_kind":"pith_short_12","alias_value":"T5FDY6BIABYN","created_at":"2026-05-18T12:31:43Z"},{"alias_kind":"pith_short_16","alias_value":"T5FDY6BIABYNIMUE","created_at":"2026-05-18T12:31:43Z"},{"alias_kind":"pith_short_8","alias_value":"T5FDY6BI","created_at":"2026-05-18T12:31:43Z"}],"graph_snapshots":[{"event_id":"sha256:f745dd25f6072df63e5a2958db22e8485720f18d7343662767d7241a6660595e","target":"graph","created_at":"2026-05-18T00:49:40Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"Many microbial systems are known to actively reshape their proteomes in response to changes in growth conditions induced e.g. by nutritional stress or antibiotics. Part of the re-allocation accounts for the fact that, as the growth rate is limited by targeting specific metabolic activities, cells simply respond by fine-tuning their proteome to invest more resources into the limiting activity (i.e. by synthesizing more proteins devoted to it). However, this is often accompanied by an overall re-organization of metabolism, aimed at improving the growth yield under limitation by re-wiring resourc","authors_text":"Andrea De Martino, Enzo Marinari, Matteo Mori","cross_cats":["cond-mat.dis-nn","physics.bio-ph"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.MN","submitted_at":"2017-03-02T12:15:14Z","title":"A yield-cost tradeoff governs Escherichia coli's decision between fermentation and respiration in carbon-limited growth"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1703.00748","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:0700d2f68f0ae3e19a9a16f68b65fd852b7ff0330d5ae9acb1bd1d90233c92a5","target":"record","created_at":"2026-05-18T00:49:40Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"76c4fd9453c95448c0bb21b5998af94f1aed0bd6e65fd8d2845b3ed8780bfc55","cross_cats_sorted":["cond-mat.dis-nn","physics.bio-ph"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.MN","submitted_at":"2017-03-02T12:15:14Z","title_canon_sha256":"f2265b5d8380b38b0944dbe205bdaf72383585489b93f6ddfe1a0954c656e583"},"schema_version":"1.0","source":{"id":"1703.00748","kind":"arxiv","version":1}},"canonical_sha256":"9f4a3c78280070d43284fe77b4968ff33b53bdac50b9eeb085104b21ff25de5a","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"9f4a3c78280070d43284fe77b4968ff33b53bdac50b9eeb085104b21ff25de5a","first_computed_at":"2026-05-18T00:49:40.878278Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T00:49:40.878278Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"yEGneCGo9d1VodC8VNoLQnYQKFugIt3aCDbcm7YxJVi7iHH4EIlCsQ9wuY91jAxML7dfvDixRu6ynN52IE6WAQ==","signature_status":"signed_v1","signed_at":"2026-05-18T00:49:40.878926Z","signed_message":"canonical_sha256_bytes"},"source_id":"1703.00748","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:0700d2f68f0ae3e19a9a16f68b65fd852b7ff0330d5ae9acb1bd1d90233c92a5","sha256:f745dd25f6072df63e5a2958db22e8485720f18d7343662767d7241a6660595e"],"state_sha256":"7bdd2a06dc31e04bb27931b85310870c317ece58ced9bdb404400d80da00fa2a"}