{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2026:TD3PFP7BPRU2GVKIU4KKPVVCYR","short_pith_number":"pith:TD3PFP7B","canonical_record":{"source":{"id":"2607.20122","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cond-mat.soft","submitted_at":"2026-07-22T13:25:12Z","cross_cats_sorted":["physics.comp-ph"],"title_canon_sha256":"1213520fed873319f2e20e304b8a1e8d89b6b7ad13d0bf72a72ca50369a8a4f6","abstract_canon_sha256":"6fe21d6f922c6df30bbd2df51337713bc12ae04c6399a75319023a5ff51f3a32"},"schema_version":"1.0"},"canonical_sha256":"98f6f2bfe17c69a35548a714a7d6a2c474716d1c4bdd3fcfc3a4b365c9c2db62","source":{"kind":"arxiv","id":"2607.20122","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2607.20122","created_at":"2026-07-23T01:25:02Z"},{"alias_kind":"arxiv_version","alias_value":"2607.20122v1","created_at":"2026-07-23T01:25:02Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2607.20122","created_at":"2026-07-23T01:25:02Z"},{"alias_kind":"pith_short_12","alias_value":"TD3PFP7BPRU2","created_at":"2026-07-23T01:25:02Z"},{"alias_kind":"pith_short_16","alias_value":"TD3PFP7BPRU2GVKI","created_at":"2026-07-23T01:25:02Z"},{"alias_kind":"pith_short_8","alias_value":"TD3PFP7B","created_at":"2026-07-23T01:25:02Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2026:TD3PFP7BPRU2GVKIU4KKPVVCYR","target":"record","payload":{"canonical_record":{"source":{"id":"2607.20122","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cond-mat.soft","submitted_at":"2026-07-22T13:25:12Z","cross_cats_sorted":["physics.comp-ph"],"title_canon_sha256":"1213520fed873319f2e20e304b8a1e8d89b6b7ad13d0bf72a72ca50369a8a4f6","abstract_canon_sha256":"6fe21d6f922c6df30bbd2df51337713bc12ae04c6399a75319023a5ff51f3a32"},"schema_version":"1.0"},"canonical_sha256":"98f6f2bfe17c69a35548a714a7d6a2c474716d1c4bdd3fcfc3a4b365c9c2db62","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-07-23T01:25:02.561104Z","signature_b64":"E6UMy9Zz1JoVU2AgPq6qLcvkEamyuffQO/1JK4gmfjHIkAAaBJ3yIrvPIpd5plY9ew+HsdHRIBkqiaIbWDe6Bw==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"98f6f2bfe17c69a35548a714a7d6a2c474716d1c4bdd3fcfc3a4b365c9c2db62","last_reissued_at":"2026-07-23T01:25:02.560280Z","signature_status":"signed_v1","first_computed_at":"2026-07-23T01:25:02.560280Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"2607.20122","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-23T01:25:02Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"zHOQOqtaFaSK45il+nF+e0wGRL4xAX0ErUHmtj9zvRbRLYDMNuwSLbnalaZCherbcgwEfPrbiknDzd5t0FafDQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-02T03:50:38.943860Z"},"content_sha256":"4081b8395d9420516ae13556380c9befba7dbe094cd300599b8780e2620519f2","schema_version":"1.0","event_id":"sha256:4081b8395d9420516ae13556380c9befba7dbe094cd300599b8780e2620519f2"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2026:TD3PFP7BPRU2GVKIU4KKPVVCYR","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Let's Stalk About Membranes: Committor-Based Enhanced Sampling of Stalk Formation","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["physics.comp-ph"],"primary_cat":"cond-mat.soft","authors_text":"Davide Bochicchio, Enrico Trizio, Giorgia Rossi, Giulia Rossi, Michele Parrinello","submitted_at":"2026-07-22T13:25:12Z","abstract_excerpt":"Membrane fusion is essential for cellular communication and function, and understanding how two lipid bilayers merge is key to informing therapeutic strategies. Functionalized nanoparticles have recently emerged as synthetic fusogens, but the molecular mechanisms driving this process remain unclear, partly because fusion involves transitions over high free-energy barriers, difficult to capture in molecular simulations. While enhanced sampling methods can address this problem, they also rely on the definition of collective variables, which are especially hard to define for fusion, as it arises "},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2607.20122","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2607.20122/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-23T01:25:02Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"voHSVFZ5qlXL/Gl3UPRm7WZDRqrrsO2F2rvC80tKG/PcEgdFhcubZMHqMdPx/ai6uNry/4/nDsHmTq7D1DV6Bw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-02T03:50:38.944503Z"},"content_sha256":"d269b8d9756b2813d69880f21811e1f8d754288ee023bcc6b82a348655457db9","schema_version":"1.0","event_id":"sha256:d269b8d9756b2813d69880f21811e1f8d754288ee023bcc6b82a348655457db9"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/TD3PFP7BPRU2GVKIU4KKPVVCYR/bundle.json","state_url":"https://pith.science/pith/TD3PFP7BPRU2GVKIU4KKPVVCYR/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/TD3PFP7BPRU2GVKIU4KKPVVCYR/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-08-02T03:50:38Z","links":{"resolver":"https://pith.science/pith/TD3PFP7BPRU2GVKIU4KKPVVCYR","bundle":"https://pith.science/pith/TD3PFP7BPRU2GVKIU4KKPVVCYR/bundle.json","state":"https://pith.science/pith/TD3PFP7BPRU2GVKIU4KKPVVCYR/state.json","well_known_bundle":"https://pith.science/.well-known/pith/TD3PFP7BPRU2GVKIU4KKPVVCYR/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2026:TD3PFP7BPRU2GVKIU4KKPVVCYR","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"6fe21d6f922c6df30bbd2df51337713bc12ae04c6399a75319023a5ff51f3a32","cross_cats_sorted":["physics.comp-ph"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cond-mat.soft","submitted_at":"2026-07-22T13:25:12Z","title_canon_sha256":"1213520fed873319f2e20e304b8a1e8d89b6b7ad13d0bf72a72ca50369a8a4f6"},"schema_version":"1.0","source":{"id":"2607.20122","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2607.20122","created_at":"2026-07-23T01:25:02Z"},{"alias_kind":"arxiv_version","alias_value":"2607.20122v1","created_at":"2026-07-23T01:25:02Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2607.20122","created_at":"2026-07-23T01:25:02Z"},{"alias_kind":"pith_short_12","alias_value":"TD3PFP7BPRU2","created_at":"2026-07-23T01:25:02Z"},{"alias_kind":"pith_short_16","alias_value":"TD3PFP7BPRU2GVKI","created_at":"2026-07-23T01:25:02Z"},{"alias_kind":"pith_short_8","alias_value":"TD3PFP7B","created_at":"2026-07-23T01:25:02Z"}],"graph_snapshots":[{"event_id":"sha256:d269b8d9756b2813d69880f21811e1f8d754288ee023bcc6b82a348655457db9","target":"graph","created_at":"2026-07-23T01:25:02Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2607.20122/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"Membrane fusion is essential for cellular communication and function, and understanding how two lipid bilayers merge is key to informing therapeutic strategies. Functionalized nanoparticles have recently emerged as synthetic fusogens, but the molecular mechanisms driving this process remain unclear, partly because fusion involves transitions over high free-energy barriers, difficult to capture in molecular simulations. While enhanced sampling methods can address this problem, they also rely on the definition of collective variables, which are especially hard to define for fusion, as it arises ","authors_text":"Davide Bochicchio, Enrico Trizio, Giorgia Rossi, Giulia Rossi, Michele Parrinello","cross_cats":["physics.comp-ph"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cond-mat.soft","submitted_at":"2026-07-22T13:25:12Z","title":"Let's Stalk About Membranes: Committor-Based Enhanced Sampling of Stalk Formation"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2607.20122","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:4081b8395d9420516ae13556380c9befba7dbe094cd300599b8780e2620519f2","target":"record","created_at":"2026-07-23T01:25:02Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"6fe21d6f922c6df30bbd2df51337713bc12ae04c6399a75319023a5ff51f3a32","cross_cats_sorted":["physics.comp-ph"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cond-mat.soft","submitted_at":"2026-07-22T13:25:12Z","title_canon_sha256":"1213520fed873319f2e20e304b8a1e8d89b6b7ad13d0bf72a72ca50369a8a4f6"},"schema_version":"1.0","source":{"id":"2607.20122","kind":"arxiv","version":1}},"canonical_sha256":"98f6f2bfe17c69a35548a714a7d6a2c474716d1c4bdd3fcfc3a4b365c9c2db62","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"98f6f2bfe17c69a35548a714a7d6a2c474716d1c4bdd3fcfc3a4b365c9c2db62","first_computed_at":"2026-07-23T01:25:02.560280Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-23T01:25:02.560280Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"E6UMy9Zz1JoVU2AgPq6qLcvkEamyuffQO/1JK4gmfjHIkAAaBJ3yIrvPIpd5plY9ew+HsdHRIBkqiaIbWDe6Bw==","signature_status":"signed_v1","signed_at":"2026-07-23T01:25:02.561104Z","signed_message":"canonical_sha256_bytes"},"source_id":"2607.20122","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:4081b8395d9420516ae13556380c9befba7dbe094cd300599b8780e2620519f2","sha256:d269b8d9756b2813d69880f21811e1f8d754288ee023bcc6b82a348655457db9"],"state_sha256":"efabf6da91be74197da8914ac067f11fd73cc89d968674e8596aceece80b38b2"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"WZSAU4Bu4zrx9L7WjE+IOIBmdHFUCIhhwEmSoiK8V2siHna2iXCtgwMuqGrPSezXUw7u9V06lLlZWrl6ukmbAQ==","signed_message":"bundle_sha256_bytes","signed_at":"2026-08-02T03:50:38.950070Z","bundle_sha256":"9a705ecdeec74f9e5dc05d333c96d383a2058c83e2d7f3c964b7edb923f19ef5"}}