{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2019:TFLLQHZ2JTZ6L6ONL7XYLY2L2N","short_pith_number":"pith:TFLLQHZ2","canonical_record":{"source":{"id":"1903.10376","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.med-ph","submitted_at":"2019-03-19T17:32:04Z","cross_cats_sorted":[],"title_canon_sha256":"829baf4e55e635ddcd38df7ef854219677f4df389f3908908014c563303227fb","abstract_canon_sha256":"4aaa19dce4c3430e57e19dcb7bfa648643b647355b6fa4ede608643e2d44063e"},"schema_version":"1.0"},"canonical_sha256":"9956b81f3a4cf3e5f9cd5fef85e34bd35abb48c6135f29d66fd0a757ff4d8f41","source":{"kind":"arxiv","id":"1903.10376","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1903.10376","created_at":"2026-05-17T23:50:29Z"},{"alias_kind":"arxiv_version","alias_value":"1903.10376v1","created_at":"2026-05-17T23:50:29Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1903.10376","created_at":"2026-05-17T23:50:29Z"},{"alias_kind":"pith_short_12","alias_value":"TFLLQHZ2JTZ6","created_at":"2026-05-18T12:33:27Z"},{"alias_kind":"pith_short_16","alias_value":"TFLLQHZ2JTZ6L6ON","created_at":"2026-05-18T12:33:27Z"},{"alias_kind":"pith_short_8","alias_value":"TFLLQHZ2","created_at":"2026-05-18T12:33:27Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2019:TFLLQHZ2JTZ6L6ONL7XYLY2L2N","target":"record","payload":{"canonical_record":{"source":{"id":"1903.10376","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.med-ph","submitted_at":"2019-03-19T17:32:04Z","cross_cats_sorted":[],"title_canon_sha256":"829baf4e55e635ddcd38df7ef854219677f4df389f3908908014c563303227fb","abstract_canon_sha256":"4aaa19dce4c3430e57e19dcb7bfa648643b647355b6fa4ede608643e2d44063e"},"schema_version":"1.0"},"canonical_sha256":"9956b81f3a4cf3e5f9cd5fef85e34bd35abb48c6135f29d66fd0a757ff4d8f41","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-17T23:50:29.670465Z","signature_b64":"VgS+iJS8Ul+fd0xSm4sgJoEWv/Ob0FnudNvlcUDBiUVrbwnHybnO4T6OYAEKKCNBUlRkoe2AkJPGfN8OrwlWAQ==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"9956b81f3a4cf3e5f9cd5fef85e34bd35abb48c6135f29d66fd0a757ff4d8f41","last_reissued_at":"2026-05-17T23:50:29.669933Z","signature_status":"signed_v1","first_computed_at":"2026-05-17T23:50:29.669933Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1903.10376","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-17T23:50:29Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"SRvoeBiq0I/vVVgmbVK8jcnt4i0anqJPnHDFC295vUTP2auwQvAmxCJvTGcmy100k7hUTjU8y5RMzwGfHcnFDQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-29T22:30:23.256443Z"},"content_sha256":"805ea3db96a2f2382951058e17fe2023a48419425efd1813aaaaa548117f9696","schema_version":"1.0","event_id":"sha256:805ea3db96a2f2382951058e17fe2023a48419425efd1813aaaaa548117f9696"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2019:TFLLQHZ2JTZ6L6ONL7XYLY2L2N","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Two-dimensional Magnetization-Transfer - CPMG MRI reveals tract- specific signatures in fixed rat spinal cord","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"physics.med-ph","authors_text":"Noam Shemesh, Teresa Serradas Duarte","submitted_at":"2019-03-19T17:32:04Z","abstract_excerpt":"Multiexponential T2 (MET2) Relaxometry and Magnetization Transfer (MT) are among the most promising MRI-derived techniques for white matter (WM) characterization. Both techniques are shown to have histologically correlated sensitivity to myelin, but these correlations are not fully understood. Furthermore, MET2 and MT reports on different features of WM, thus being specific to different (patho)physiological states. Two-dimensional studies, such as those commonly used in NMR, have been rarely performed in this context. Here, off-resonance irradiation effects on MET2 components were evaluated in"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1903.10376","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-17T23:50:29Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"QMMPxaxVJRtxQsBc0TyFQGEhsax2feDLm1s2mL0rnrOdLI3aX/LJD8diBqhx/51r1RVcVIDgShR1UfzScOX5BQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-29T22:30:23.257165Z"},"content_sha256":"a6d6217bfa2440ffb9c36ad00199b52a081bbf284c273c6b3334b749522540d5","schema_version":"1.0","event_id":"sha256:a6d6217bfa2440ffb9c36ad00199b52a081bbf284c273c6b3334b749522540d5"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/TFLLQHZ2JTZ6L6ONL7XYLY2L2N/bundle.json","state_url":"https://pith.science/pith/TFLLQHZ2JTZ6L6ONL7XYLY2L2N/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/TFLLQHZ2JTZ6L6ONL7XYLY2L2N/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-05-29T22:30:23Z","links":{"resolver":"https://pith.science/pith/TFLLQHZ2JTZ6L6ONL7XYLY2L2N","bundle":"https://pith.science/pith/TFLLQHZ2JTZ6L6ONL7XYLY2L2N/bundle.json","state":"https://pith.science/pith/TFLLQHZ2JTZ6L6ONL7XYLY2L2N/state.json","well_known_bundle":"https://pith.science/.well-known/pith/TFLLQHZ2JTZ6L6ONL7XYLY2L2N/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2019:TFLLQHZ2JTZ6L6ONL7XYLY2L2N","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"4aaa19dce4c3430e57e19dcb7bfa648643b647355b6fa4ede608643e2d44063e","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.med-ph","submitted_at":"2019-03-19T17:32:04Z","title_canon_sha256":"829baf4e55e635ddcd38df7ef854219677f4df389f3908908014c563303227fb"},"schema_version":"1.0","source":{"id":"1903.10376","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1903.10376","created_at":"2026-05-17T23:50:29Z"},{"alias_kind":"arxiv_version","alias_value":"1903.10376v1","created_at":"2026-05-17T23:50:29Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1903.10376","created_at":"2026-05-17T23:50:29Z"},{"alias_kind":"pith_short_12","alias_value":"TFLLQHZ2JTZ6","created_at":"2026-05-18T12:33:27Z"},{"alias_kind":"pith_short_16","alias_value":"TFLLQHZ2JTZ6L6ON","created_at":"2026-05-18T12:33:27Z"},{"alias_kind":"pith_short_8","alias_value":"TFLLQHZ2","created_at":"2026-05-18T12:33:27Z"}],"graph_snapshots":[{"event_id":"sha256:a6d6217bfa2440ffb9c36ad00199b52a081bbf284c273c6b3334b749522540d5","target":"graph","created_at":"2026-05-17T23:50:29Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"Multiexponential T2 (MET2) Relaxometry and Magnetization Transfer (MT) are among the most promising MRI-derived techniques for white matter (WM) characterization. Both techniques are shown to have histologically correlated sensitivity to myelin, but these correlations are not fully understood. Furthermore, MET2 and MT reports on different features of WM, thus being specific to different (patho)physiological states. Two-dimensional studies, such as those commonly used in NMR, have been rarely performed in this context. Here, off-resonance irradiation effects on MET2 components were evaluated in","authors_text":"Noam Shemesh, Teresa Serradas Duarte","cross_cats":[],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.med-ph","submitted_at":"2019-03-19T17:32:04Z","title":"Two-dimensional Magnetization-Transfer - CPMG MRI reveals tract- specific signatures in fixed rat spinal cord"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1903.10376","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:805ea3db96a2f2382951058e17fe2023a48419425efd1813aaaaa548117f9696","target":"record","created_at":"2026-05-17T23:50:29Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"4aaa19dce4c3430e57e19dcb7bfa648643b647355b6fa4ede608643e2d44063e","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.med-ph","submitted_at":"2019-03-19T17:32:04Z","title_canon_sha256":"829baf4e55e635ddcd38df7ef854219677f4df389f3908908014c563303227fb"},"schema_version":"1.0","source":{"id":"1903.10376","kind":"arxiv","version":1}},"canonical_sha256":"9956b81f3a4cf3e5f9cd5fef85e34bd35abb48c6135f29d66fd0a757ff4d8f41","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"9956b81f3a4cf3e5f9cd5fef85e34bd35abb48c6135f29d66fd0a757ff4d8f41","first_computed_at":"2026-05-17T23:50:29.669933Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-17T23:50:29.669933Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"VgS+iJS8Ul+fd0xSm4sgJoEWv/Ob0FnudNvlcUDBiUVrbwnHybnO4T6OYAEKKCNBUlRkoe2AkJPGfN8OrwlWAQ==","signature_status":"signed_v1","signed_at":"2026-05-17T23:50:29.670465Z","signed_message":"canonical_sha256_bytes"},"source_id":"1903.10376","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:805ea3db96a2f2382951058e17fe2023a48419425efd1813aaaaa548117f9696","sha256:a6d6217bfa2440ffb9c36ad00199b52a081bbf284c273c6b3334b749522540d5"],"state_sha256":"752e5700675f6ae8e64b443be826f1db6ccb253ccb5105dbdf282beec20d2f3e"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"SXkUUvzWlNEfZIgvD131gDbteoZm/2aGw9ksDV8tr/Nreo9FVH+nGvgLTIORBCoeeN8JZDxoERhSrF5N/A1qDw==","signed_message":"bundle_sha256_bytes","signed_at":"2026-05-29T22:30:23.260960Z","bundle_sha256":"2d8e4c5eae38bb47ed3418b6c995c70340adcdeb437d955e17278ff142d07b68"}}