{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2013:U26JNDFJRDIYEDDQNEUYAB3ADK","short_pith_number":"pith:U26JNDFJ","canonical_record":{"source":{"id":"1302.6614","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.chem-ph","submitted_at":"2013-02-26T22:24:35Z","cross_cats_sorted":["q-bio.BM"],"title_canon_sha256":"a68bd4a64e21f5138dcf9c213be78e21eb5b654ca3531079ba10cb722427adf1","abstract_canon_sha256":"5ab7aee8bd3b36c3ccaa949c338267565058cc6803d4fc2710e6e701c0b34b19"},"schema_version":"1.0"},"canonical_sha256":"a6bc968ca988d1820c7069298007601aa4990cfd51de60d3b186f28ca610b09d","source":{"kind":"arxiv","id":"1302.6614","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1302.6614","created_at":"2026-05-18T01:51:26Z"},{"alias_kind":"arxiv_version","alias_value":"1302.6614v1","created_at":"2026-05-18T01:51:26Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1302.6614","created_at":"2026-05-18T01:51:26Z"},{"alias_kind":"pith_short_12","alias_value":"U26JNDFJRDIY","created_at":"2026-05-18T12:28:02Z"},{"alias_kind":"pith_short_16","alias_value":"U26JNDFJRDIYEDDQ","created_at":"2026-05-18T12:28:02Z"},{"alias_kind":"pith_short_8","alias_value":"U26JNDFJ","created_at":"2026-05-18T12:28:02Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2013:U26JNDFJRDIYEDDQNEUYAB3ADK","target":"record","payload":{"canonical_record":{"source":{"id":"1302.6614","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.chem-ph","submitted_at":"2013-02-26T22:24:35Z","cross_cats_sorted":["q-bio.BM"],"title_canon_sha256":"a68bd4a64e21f5138dcf9c213be78e21eb5b654ca3531079ba10cb722427adf1","abstract_canon_sha256":"5ab7aee8bd3b36c3ccaa949c338267565058cc6803d4fc2710e6e701c0b34b19"},"schema_version":"1.0"},"canonical_sha256":"a6bc968ca988d1820c7069298007601aa4990cfd51de60d3b186f28ca610b09d","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T01:51:26.986347Z","signature_b64":"WQ+s31R/1Vn/T3IUDkWeLCaP40S60IdRqMI4hsR0aRglIbJII8nVwS+914KBHYzTh0gZgXpCjsHGOAM1eU1NAg==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"a6bc968ca988d1820c7069298007601aa4990cfd51de60d3b186f28ca610b09d","last_reissued_at":"2026-05-18T01:51:26.985635Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T01:51:26.985635Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1302.6614","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T01:51:26Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"I36vES/XqdaHxgY3EW9LNtz8aFjAzg8zZxyuBOYfr8fZqZwh0FDCZGS5/OFH9EJkAKIuNAxidO3/MyORcUihAg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-20T22:03:22.832232Z"},"content_sha256":"aa9392027f9e3102533b8ffd0514f786bbae2e4e097ba360931b17ee85dac951","schema_version":"1.0","event_id":"sha256:aa9392027f9e3102533b8ffd0514f786bbae2e4e097ba360931b17ee85dac951"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2013:U26JNDFJRDIYEDDQNEUYAB3ADK","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Identification of slow molecular order parameters for Markov model construction","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["q-bio.BM"],"primary_cat":"physics.chem-ph","authors_text":"Fabian Paul, Frank No\\'e, Gianni de Fabritiis, Guillermo Perez-Hernandez, Toni Giorgino","submitted_at":"2013-02-26T22:24:35Z","abstract_excerpt":"A goal in the kinetic characterization of a macromolecular system is the description of its slow relaxation processes, involving (i) identification of the structural changes involved in these processes, and (ii) estimation of the rates or timescales at which these slow processes occur. Most of the approaches to this task, including Markov models, Master-equation models, and kinetic network models, start by discretizing the high-dimensional state space and then characterize relaxation processes in terms of the eigenvectors and eigenvalues of a discrete transition matrix. The practical success o"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1302.6614","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T01:51:26Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"Wj9E2WvokILD0fT5laj1nqDYrG12I4JC9REjlrsMZRMo3g3h6DJjrc95OlzGDLVllJx2y/bRqNUaj5KeZI8VBQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-20T22:03:22.832933Z"},"content_sha256":"91e4cf0a7580944573120e6c1702bd9a8367f1977c6d400ca117d8e224e2e96b","schema_version":"1.0","event_id":"sha256:91e4cf0a7580944573120e6c1702bd9a8367f1977c6d400ca117d8e224e2e96b"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/U26JNDFJRDIYEDDQNEUYAB3ADK/bundle.json","state_url":"https://pith.science/pith/U26JNDFJRDIYEDDQNEUYAB3ADK/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/U26JNDFJRDIYEDDQNEUYAB3ADK/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-05-20T22:03:22Z","links":{"resolver":"https://pith.science/pith/U26JNDFJRDIYEDDQNEUYAB3ADK","bundle":"https://pith.science/pith/U26JNDFJRDIYEDDQNEUYAB3ADK/bundle.json","state":"https://pith.science/pith/U26JNDFJRDIYEDDQNEUYAB3ADK/state.json","well_known_bundle":"https://pith.science/.well-known/pith/U26JNDFJRDIYEDDQNEUYAB3ADK/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2013:U26JNDFJRDIYEDDQNEUYAB3ADK","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"5ab7aee8bd3b36c3ccaa949c338267565058cc6803d4fc2710e6e701c0b34b19","cross_cats_sorted":["q-bio.BM"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.chem-ph","submitted_at":"2013-02-26T22:24:35Z","title_canon_sha256":"a68bd4a64e21f5138dcf9c213be78e21eb5b654ca3531079ba10cb722427adf1"},"schema_version":"1.0","source":{"id":"1302.6614","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1302.6614","created_at":"2026-05-18T01:51:26Z"},{"alias_kind":"arxiv_version","alias_value":"1302.6614v1","created_at":"2026-05-18T01:51:26Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1302.6614","created_at":"2026-05-18T01:51:26Z"},{"alias_kind":"pith_short_12","alias_value":"U26JNDFJRDIY","created_at":"2026-05-18T12:28:02Z"},{"alias_kind":"pith_short_16","alias_value":"U26JNDFJRDIYEDDQ","created_at":"2026-05-18T12:28:02Z"},{"alias_kind":"pith_short_8","alias_value":"U26JNDFJ","created_at":"2026-05-18T12:28:02Z"}],"graph_snapshots":[{"event_id":"sha256:91e4cf0a7580944573120e6c1702bd9a8367f1977c6d400ca117d8e224e2e96b","target":"graph","created_at":"2026-05-18T01:51:26Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"A goal in the kinetic characterization of a macromolecular system is the description of its slow relaxation processes, involving (i) identification of the structural changes involved in these processes, and (ii) estimation of the rates or timescales at which these slow processes occur. Most of the approaches to this task, including Markov models, Master-equation models, and kinetic network models, start by discretizing the high-dimensional state space and then characterize relaxation processes in terms of the eigenvectors and eigenvalues of a discrete transition matrix. The practical success o","authors_text":"Fabian Paul, Frank No\\'e, Gianni de Fabritiis, Guillermo Perez-Hernandez, Toni Giorgino","cross_cats":["q-bio.BM"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.chem-ph","submitted_at":"2013-02-26T22:24:35Z","title":"Identification of slow molecular order parameters for Markov model construction"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1302.6614","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:aa9392027f9e3102533b8ffd0514f786bbae2e4e097ba360931b17ee85dac951","target":"record","created_at":"2026-05-18T01:51:26Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"5ab7aee8bd3b36c3ccaa949c338267565058cc6803d4fc2710e6e701c0b34b19","cross_cats_sorted":["q-bio.BM"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.chem-ph","submitted_at":"2013-02-26T22:24:35Z","title_canon_sha256":"a68bd4a64e21f5138dcf9c213be78e21eb5b654ca3531079ba10cb722427adf1"},"schema_version":"1.0","source":{"id":"1302.6614","kind":"arxiv","version":1}},"canonical_sha256":"a6bc968ca988d1820c7069298007601aa4990cfd51de60d3b186f28ca610b09d","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"a6bc968ca988d1820c7069298007601aa4990cfd51de60d3b186f28ca610b09d","first_computed_at":"2026-05-18T01:51:26.985635Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T01:51:26.985635Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"WQ+s31R/1Vn/T3IUDkWeLCaP40S60IdRqMI4hsR0aRglIbJII8nVwS+914KBHYzTh0gZgXpCjsHGOAM1eU1NAg==","signature_status":"signed_v1","signed_at":"2026-05-18T01:51:26.986347Z","signed_message":"canonical_sha256_bytes"},"source_id":"1302.6614","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:aa9392027f9e3102533b8ffd0514f786bbae2e4e097ba360931b17ee85dac951","sha256:91e4cf0a7580944573120e6c1702bd9a8367f1977c6d400ca117d8e224e2e96b"],"state_sha256":"97aa940540cebbe1bf84188fbff360502892dd9673d1e32040077bfad89cf09f"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"NxAzl1D9mu9RMd6LIM60HCyGvDm77SoGuWeo1sTjpW8Ul/nuAhoxAw1QJM1RsTuYX2HJxK1B8+JuRlgPKMXnCw==","signed_message":"bundle_sha256_bytes","signed_at":"2026-05-20T22:03:22.836967Z","bundle_sha256":"94208576ba231635aa7f19772a6bd630a3ec802fb7eb06b45a1e4d7e7153f373"}}