{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2024:U4GCJNCNGTWDF3N5DTXV324ZVH","short_pith_number":"pith:U4GCJNCN","canonical_record":{"source":{"id":"2404.05913","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"cs.LG","submitted_at":"2024-04-09T00:07:16Z","cross_cats_sorted":["cs.AI"],"title_canon_sha256":"ddb9f783b0a1367f197fd6eb54971d47d382a21ed5d4a2046db06018bd88130f","abstract_canon_sha256":"b89b53b38505e0e9ae631d5b6bd6d0b0e91b2b0db7f3c7d1e2f1d4a670e4d178"},"schema_version":"1.0"},"canonical_sha256":"a70c24b44d34ec32edbd1cef5deb99a9d6e0891e7801811009d7039a28e3edb2","source":{"kind":"arxiv","id":"2404.05913","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2404.05913","created_at":"2026-07-05T08:06:01Z"},{"alias_kind":"arxiv_version","alias_value":"2404.05913v1","created_at":"2026-07-05T08:06:01Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2404.05913","created_at":"2026-07-05T08:06:01Z"},{"alias_kind":"pith_short_12","alias_value":"U4GCJNCNGTWD","created_at":"2026-07-05T08:06:01Z"},{"alias_kind":"pith_short_16","alias_value":"U4GCJNCNGTWDF3N5","created_at":"2026-07-05T08:06:01Z"},{"alias_kind":"pith_short_8","alias_value":"U4GCJNCN","created_at":"2026-07-05T08:06:01Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2024:U4GCJNCNGTWDF3N5DTXV324ZVH","target":"record","payload":{"canonical_record":{"source":{"id":"2404.05913","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"cs.LG","submitted_at":"2024-04-09T00:07:16Z","cross_cats_sorted":["cs.AI"],"title_canon_sha256":"ddb9f783b0a1367f197fd6eb54971d47d382a21ed5d4a2046db06018bd88130f","abstract_canon_sha256":"b89b53b38505e0e9ae631d5b6bd6d0b0e91b2b0db7f3c7d1e2f1d4a670e4d178"},"schema_version":"1.0"},"canonical_sha256":"a70c24b44d34ec32edbd1cef5deb99a9d6e0891e7801811009d7039a28e3edb2","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-07-05T08:06:01.132413Z","signature_b64":"Cglnwry8MKVD4tqVvSqV0ITgzg/GCddbtXMiF8iEAzvVeNvVu+L58Wu7G7W660OxVnp4Pfr+tDCYgJfeoQePBQ==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"a70c24b44d34ec32edbd1cef5deb99a9d6e0891e7801811009d7039a28e3edb2","last_reissued_at":"2026-07-05T08:06:01.131828Z","signature_status":"signed_v1","first_computed_at":"2026-07-05T08:06:01.131828Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"2404.05913","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T08:06:01Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"YGi914EkvmXCOUonmtFcAFvHvKr1eYkkIz06txyp1bnWfY5JEodRTfUks9tclOcrp7As45PmSneN0a8Rkn15Bw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-20T00:57:49.958092Z"},"content_sha256":"25775578d523e7c5c5af0725c6af1d42fe883632bfac113129cfbc4ae186b04a","schema_version":"1.0","event_id":"sha256:25775578d523e7c5c5af0725c6af1d42fe883632bfac113129cfbc4ae186b04a"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2024:U4GCJNCNGTWDF3N5DTXV324ZVH","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Deep Reinforcement Learning for Personalized Diagnostic Decision Pathways Using Electronic Health Records: A Comparative Study on Anemia and Systemic Lupus Erythematosus","license":"http://creativecommons.org/licenses/by/4.0/","headline":"","cross_cats":["cs.AI"],"primary_cat":"cs.LG","authors_text":"Adrien Coulet, Antoine Neuraz, Lillian Muyama","submitted_at":"2024-04-09T00:07:16Z","abstract_excerpt":"Background: Clinical diagnosis is typically reached by following a series of steps recommended by guidelines authored by colleges of experts. Accordingly, guidelines play a crucial role in rationalizing clinical decisions but suffer from limitations as they are built to cover the majority of the population and fail at covering patients with uncommon conditions. Moreover, their updates are long and expensive, making them unsuitable for emerging diseases and practices.\n  Methods: Inspired by guidelines, we formulate the task of diagnosis as a sequential decision-making problem and study the use "},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2404.05913","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2404.05913/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T08:06:01Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"01kDCFSOZXNcK1hEzboHaqthjVR39EVqi089HooNDIPHE6xkcIycH0SVg+/qykVu5UdfFRXumeu0d5V8FunLDg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-20T00:57:49.958771Z"},"content_sha256":"7308302a0846e97304164d87d956bc552f43b561259286c1b2054e1ed7b8a1f9","schema_version":"1.0","event_id":"sha256:7308302a0846e97304164d87d956bc552f43b561259286c1b2054e1ed7b8a1f9"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/U4GCJNCNGTWDF3N5DTXV324ZVH/bundle.json","state_url":"https://pith.science/pith/U4GCJNCNGTWDF3N5DTXV324ZVH/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/U4GCJNCNGTWDF3N5DTXV324ZVH/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-08-20T00:57:49Z","links":{"resolver":"https://pith.science/pith/U4GCJNCNGTWDF3N5DTXV324ZVH","bundle":"https://pith.science/pith/U4GCJNCNGTWDF3N5DTXV324ZVH/bundle.json","state":"https://pith.science/pith/U4GCJNCNGTWDF3N5DTXV324ZVH/state.json","well_known_bundle":"https://pith.science/.well-known/pith/U4GCJNCNGTWDF3N5DTXV324ZVH/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2024:U4GCJNCNGTWDF3N5DTXV324ZVH","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"b89b53b38505e0e9ae631d5b6bd6d0b0e91b2b0db7f3c7d1e2f1d4a670e4d178","cross_cats_sorted":["cs.AI"],"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"cs.LG","submitted_at":"2024-04-09T00:07:16Z","title_canon_sha256":"ddb9f783b0a1367f197fd6eb54971d47d382a21ed5d4a2046db06018bd88130f"},"schema_version":"1.0","source":{"id":"2404.05913","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2404.05913","created_at":"2026-07-05T08:06:01Z"},{"alias_kind":"arxiv_version","alias_value":"2404.05913v1","created_at":"2026-07-05T08:06:01Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2404.05913","created_at":"2026-07-05T08:06:01Z"},{"alias_kind":"pith_short_12","alias_value":"U4GCJNCNGTWD","created_at":"2026-07-05T08:06:01Z"},{"alias_kind":"pith_short_16","alias_value":"U4GCJNCNGTWDF3N5","created_at":"2026-07-05T08:06:01Z"},{"alias_kind":"pith_short_8","alias_value":"U4GCJNCN","created_at":"2026-07-05T08:06:01Z"}],"graph_snapshots":[{"event_id":"sha256:7308302a0846e97304164d87d956bc552f43b561259286c1b2054e1ed7b8a1f9","target":"graph","created_at":"2026-07-05T08:06:01Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2404.05913/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"Background: Clinical diagnosis is typically reached by following a series of steps recommended by guidelines authored by colleges of experts. Accordingly, guidelines play a crucial role in rationalizing clinical decisions but suffer from limitations as they are built to cover the majority of the population and fail at covering patients with uncommon conditions. Moreover, their updates are long and expensive, making them unsuitable for emerging diseases and practices.\n  Methods: Inspired by guidelines, we formulate the task of diagnosis as a sequential decision-making problem and study the use ","authors_text":"Adrien Coulet, Antoine Neuraz, Lillian Muyama","cross_cats":["cs.AI"],"headline":"","license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"cs.LG","submitted_at":"2024-04-09T00:07:16Z","title":"Deep Reinforcement Learning for Personalized Diagnostic Decision Pathways Using Electronic Health Records: A Comparative Study on Anemia and Systemic Lupus Erythematosus"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2404.05913","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:25775578d523e7c5c5af0725c6af1d42fe883632bfac113129cfbc4ae186b04a","target":"record","created_at":"2026-07-05T08:06:01Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"b89b53b38505e0e9ae631d5b6bd6d0b0e91b2b0db7f3c7d1e2f1d4a670e4d178","cross_cats_sorted":["cs.AI"],"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"cs.LG","submitted_at":"2024-04-09T00:07:16Z","title_canon_sha256":"ddb9f783b0a1367f197fd6eb54971d47d382a21ed5d4a2046db06018bd88130f"},"schema_version":"1.0","source":{"id":"2404.05913","kind":"arxiv","version":1}},"canonical_sha256":"a70c24b44d34ec32edbd1cef5deb99a9d6e0891e7801811009d7039a28e3edb2","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"a70c24b44d34ec32edbd1cef5deb99a9d6e0891e7801811009d7039a28e3edb2","first_computed_at":"2026-07-05T08:06:01.131828Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-05T08:06:01.131828Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"Cglnwry8MKVD4tqVvSqV0ITgzg/GCddbtXMiF8iEAzvVeNvVu+L58Wu7G7W660OxVnp4Pfr+tDCYgJfeoQePBQ==","signature_status":"signed_v1","signed_at":"2026-07-05T08:06:01.132413Z","signed_message":"canonical_sha256_bytes"},"source_id":"2404.05913","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:25775578d523e7c5c5af0725c6af1d42fe883632bfac113129cfbc4ae186b04a","sha256:7308302a0846e97304164d87d956bc552f43b561259286c1b2054e1ed7b8a1f9"],"state_sha256":"8a42ac96104b5f516e0339ce70ef9e3576edb32b9635c433e7e4316a7ac15690"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"N2KTNio45hRJ0KGPLtu7XFMrRQ75zjoBPnR4JHF20MLxE1ICUgFU8AcoZ9JqgdaWIlis2F4/wxMkihSOpAkTCw==","signed_message":"bundle_sha256_bytes","signed_at":"2026-08-20T00:57:49.963683Z","bundle_sha256":"f65d1456c57f2d37b9a89b378b5834f71cee483521dc4042e61c46d28e49d35e"}}