{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2016:U6HHKQR75DMKHCJLYGXPK2FOBC","short_pith_number":"pith:U6HHKQR7","canonical_record":{"source":{"id":"1601.01580","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.NC","submitted_at":"2016-01-07T16:02:05Z","cross_cats_sorted":["math.AT"],"title_canon_sha256":"dbb37740eb391b0c16ccbaf94869f1f4b1a468ea30c6ee8e2b260489f7c3f733","abstract_canon_sha256":"989f860b9ef69a3bb4f83487651b55884df54d267ec7dc7c18b5faf509e4217a"},"schema_version":"1.0"},"canonical_sha256":"a78e75423fe8d8a3892bc1aef568ae08abb0a21cfb65ca8a3080e9ddbfc0c651","source":{"kind":"arxiv","id":"1601.01580","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1601.01580","created_at":"2026-05-18T00:42:35Z"},{"alias_kind":"arxiv_version","alias_value":"1601.01580v1","created_at":"2026-05-18T00:42:35Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1601.01580","created_at":"2026-05-18T00:42:35Z"},{"alias_kind":"pith_short_12","alias_value":"U6HHKQR75DMK","created_at":"2026-05-18T12:30:46Z"},{"alias_kind":"pith_short_16","alias_value":"U6HHKQR75DMKHCJL","created_at":"2026-05-18T12:30:46Z"},{"alias_kind":"pith_short_8","alias_value":"U6HHKQR7","created_at":"2026-05-18T12:30:46Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2016:U6HHKQR75DMKHCJLYGXPK2FOBC","target":"record","payload":{"canonical_record":{"source":{"id":"1601.01580","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.NC","submitted_at":"2016-01-07T16:02:05Z","cross_cats_sorted":["math.AT"],"title_canon_sha256":"dbb37740eb391b0c16ccbaf94869f1f4b1a468ea30c6ee8e2b260489f7c3f733","abstract_canon_sha256":"989f860b9ef69a3bb4f83487651b55884df54d267ec7dc7c18b5faf509e4217a"},"schema_version":"1.0"},"canonical_sha256":"a78e75423fe8d8a3892bc1aef568ae08abb0a21cfb65ca8a3080e9ddbfc0c651","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T00:42:35.319935Z","signature_b64":"K7vVKqkiC9Qxgx9VI8jdcD0KrGBpApn+3NOoELHSFTQLgU1DxeuNqWX8Foe/zPLrxrxYKaCVTa+TfJ5Rj9BdDQ==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"a78e75423fe8d8a3892bc1aef568ae08abb0a21cfb65ca8a3080e9ddbfc0c651","last_reissued_at":"2026-05-18T00:42:35.319253Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T00:42:35.319253Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1601.01580","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T00:42:35Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"M3EyhxAp6ZO3c6No6auLJSG57KWBowca2tX/3ITfpkC/W9OCNufs6eL74SDjOBreAD3mVj/fuf23ccS5wIC7BQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-25T05:08:56.956174Z"},"content_sha256":"9a7e844d0204bdb25f1df4ad530538329a50c06f630ff2bbfee81cb86931c933","schema_version":"1.0","event_id":"sha256:9a7e844d0204bdb25f1df4ad530538329a50c06f630ff2bbfee81cb86931c933"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2016:U6HHKQR75DMKHCJLYGXPK2FOBC","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Topological analysis of the connectome of digital reconstructions of neural microcircuits","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["math.AT"],"primary_cat":"q-bio.NC","authors_text":"Eilif Muller, Henry Markram, Katharine Turner, Kathryn Hess, Martina Scolamiero, Max Nolte, Michael Reimann, Pawe Dotko, Ran Levi","submitted_at":"2016-01-07T16:02:05Z","abstract_excerpt":"A recent publication provides the network graph for a neocortical microcircuit comprising 8 million connections between 31,000 neurons (H. Markram, et al., Reconstruction and simulation of neocortical microcircuitry, Cell, 163 (2015) no. 2, 456-492). Since traditional graph-theoretical methods may not be sufficient to understand the immense complexity of such a biological network, we explored whether methods from algebraic topology could provide a new perspective on its structural and functional organization. Structural topological analysis revealed that directed graphs representing connectivi"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1601.01580","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T00:42:35Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"NXF+ToY0Pjwln+RrCF4MzUxd7Wk77Ru+oIuTUKj3kn7KQ2tPvUsaVckH1WVf1ulGGcrnBv8hwhmMBBDNiTXACw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-25T05:08:56.956847Z"},"content_sha256":"f41786ed165e57d840e1714c84f3b4b2c035e0388d22ee6b134020c6d9772a15","schema_version":"1.0","event_id":"sha256:f41786ed165e57d840e1714c84f3b4b2c035e0388d22ee6b134020c6d9772a15"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/U6HHKQR75DMKHCJLYGXPK2FOBC/bundle.json","state_url":"https://pith.science/pith/U6HHKQR75DMKHCJLYGXPK2FOBC/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/U6HHKQR75DMKHCJLYGXPK2FOBC/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-05-25T05:08:56Z","links":{"resolver":"https://pith.science/pith/U6HHKQR75DMKHCJLYGXPK2FOBC","bundle":"https://pith.science/pith/U6HHKQR75DMKHCJLYGXPK2FOBC/bundle.json","state":"https://pith.science/pith/U6HHKQR75DMKHCJLYGXPK2FOBC/state.json","well_known_bundle":"https://pith.science/.well-known/pith/U6HHKQR75DMKHCJLYGXPK2FOBC/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2016:U6HHKQR75DMKHCJLYGXPK2FOBC","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"989f860b9ef69a3bb4f83487651b55884df54d267ec7dc7c18b5faf509e4217a","cross_cats_sorted":["math.AT"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.NC","submitted_at":"2016-01-07T16:02:05Z","title_canon_sha256":"dbb37740eb391b0c16ccbaf94869f1f4b1a468ea30c6ee8e2b260489f7c3f733"},"schema_version":"1.0","source":{"id":"1601.01580","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1601.01580","created_at":"2026-05-18T00:42:35Z"},{"alias_kind":"arxiv_version","alias_value":"1601.01580v1","created_at":"2026-05-18T00:42:35Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1601.01580","created_at":"2026-05-18T00:42:35Z"},{"alias_kind":"pith_short_12","alias_value":"U6HHKQR75DMK","created_at":"2026-05-18T12:30:46Z"},{"alias_kind":"pith_short_16","alias_value":"U6HHKQR75DMKHCJL","created_at":"2026-05-18T12:30:46Z"},{"alias_kind":"pith_short_8","alias_value":"U6HHKQR7","created_at":"2026-05-18T12:30:46Z"}],"graph_snapshots":[{"event_id":"sha256:f41786ed165e57d840e1714c84f3b4b2c035e0388d22ee6b134020c6d9772a15","target":"graph","created_at":"2026-05-18T00:42:35Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"A recent publication provides the network graph for a neocortical microcircuit comprising 8 million connections between 31,000 neurons (H. Markram, et al., Reconstruction and simulation of neocortical microcircuitry, Cell, 163 (2015) no. 2, 456-492). Since traditional graph-theoretical methods may not be sufficient to understand the immense complexity of such a biological network, we explored whether methods from algebraic topology could provide a new perspective on its structural and functional organization. Structural topological analysis revealed that directed graphs representing connectivi","authors_text":"Eilif Muller, Henry Markram, Katharine Turner, Kathryn Hess, Martina Scolamiero, Max Nolte, Michael Reimann, Pawe Dotko, Ran Levi","cross_cats":["math.AT"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.NC","submitted_at":"2016-01-07T16:02:05Z","title":"Topological analysis of the connectome of digital reconstructions of neural microcircuits"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1601.01580","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:9a7e844d0204bdb25f1df4ad530538329a50c06f630ff2bbfee81cb86931c933","target":"record","created_at":"2026-05-18T00:42:35Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"989f860b9ef69a3bb4f83487651b55884df54d267ec7dc7c18b5faf509e4217a","cross_cats_sorted":["math.AT"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.NC","submitted_at":"2016-01-07T16:02:05Z","title_canon_sha256":"dbb37740eb391b0c16ccbaf94869f1f4b1a468ea30c6ee8e2b260489f7c3f733"},"schema_version":"1.0","source":{"id":"1601.01580","kind":"arxiv","version":1}},"canonical_sha256":"a78e75423fe8d8a3892bc1aef568ae08abb0a21cfb65ca8a3080e9ddbfc0c651","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"a78e75423fe8d8a3892bc1aef568ae08abb0a21cfb65ca8a3080e9ddbfc0c651","first_computed_at":"2026-05-18T00:42:35.319253Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T00:42:35.319253Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"K7vVKqkiC9Qxgx9VI8jdcD0KrGBpApn+3NOoELHSFTQLgU1DxeuNqWX8Foe/zPLrxrxYKaCVTa+TfJ5Rj9BdDQ==","signature_status":"signed_v1","signed_at":"2026-05-18T00:42:35.319935Z","signed_message":"canonical_sha256_bytes"},"source_id":"1601.01580","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:9a7e844d0204bdb25f1df4ad530538329a50c06f630ff2bbfee81cb86931c933","sha256:f41786ed165e57d840e1714c84f3b4b2c035e0388d22ee6b134020c6d9772a15"],"state_sha256":"76b333e32f4b5cfb864b36487fe57137ef65e046c8cda30574f4c33ba13b7736"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"WrznDYWfwRaFL45l0cMiIwKIUfZhpQKiVx6emz0SB6//1yfiZxsm9K8ncOtLvsqwnhiZb5VvFRr6iaSdyah/AA==","signed_message":"bundle_sha256_bytes","signed_at":"2026-05-25T05:08:56.960355Z","bundle_sha256":"ae913a9cf6a0cc0a103f2f5d85d367d86940c5e820aa27e75de43681ff6278d1"}}