{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2016:UGOOI7EIHWGI6PF2G77PGURZPY","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"3569a0f4daeed2417dabe233bf0cf4cd0033378f0dc96fb8fdcac1ee7f37a1ab","cross_cats_sorted":["cond-mat.soft"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.CB","submitted_at":"2016-01-08T16:15:40Z","title_canon_sha256":"d38a615f6e20abf5e58f0ee1639de00b24152235c42bf83e34c731f64a17a275"},"schema_version":"1.0","source":{"id":"1601.01927","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1601.01927","created_at":"2026-05-18T01:23:11Z"},{"alias_kind":"arxiv_version","alias_value":"1601.01927v1","created_at":"2026-05-18T01:23:11Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1601.01927","created_at":"2026-05-18T01:23:11Z"},{"alias_kind":"pith_short_12","alias_value":"UGOOI7EIHWGI","created_at":"2026-05-18T12:30:46Z"},{"alias_kind":"pith_short_16","alias_value":"UGOOI7EIHWGI6PF2","created_at":"2026-05-18T12:30:46Z"},{"alias_kind":"pith_short_8","alias_value":"UGOOI7EI","created_at":"2026-05-18T12:30:46Z"}],"graph_snapshots":[{"event_id":"sha256:0d06f5cd0bd55d9d7dd22e265534fdb9dd9cb5fd173540f8c41b987d326fe7e3","target":"graph","created_at":"2026-05-18T01:23:11Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"The ability of detecting and separating CTCs can play a key role in early cancer detection and treatment. In recent years, there has been growing interest in using deformability-based CTC separation microfilters due to their simplicity and low cost. Most of previous studies in this area are mainly based on experimental work. Although experimental research provides useful insights in designing CTC separation devices, there is still a lack of design guidelines based on fundamental understandings of the cell separation process in the filers. While experimental efforts face challenges especially m","authors_text":"Jie Xu, Mohammad Aghaamoo, Xiaolin Chen, Zhifeng Zhang","cross_cats":["cond-mat.soft"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.CB","submitted_at":"2016-01-08T16:15:40Z","title":"Deformability-based circulating tumor cell separation with conical-shaped microfilters: concept, optimization and design criteria"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1601.01927","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:18685fa8fc62614cc3374410426af64fb35b869bdec4e309f65dab396302f6b8","target":"record","created_at":"2026-05-18T01:23:11Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"3569a0f4daeed2417dabe233bf0cf4cd0033378f0dc96fb8fdcac1ee7f37a1ab","cross_cats_sorted":["cond-mat.soft"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.CB","submitted_at":"2016-01-08T16:15:40Z","title_canon_sha256":"d38a615f6e20abf5e58f0ee1639de00b24152235c42bf83e34c731f64a17a275"},"schema_version":"1.0","source":{"id":"1601.01927","kind":"arxiv","version":1}},"canonical_sha256":"a19ce47c883d8c8f3cba37fef352397e0d1342f500174949987ec8382185bfbf","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"a19ce47c883d8c8f3cba37fef352397e0d1342f500174949987ec8382185bfbf","first_computed_at":"2026-05-18T01:23:11.047908Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T01:23:11.047908Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"TZwg2FF1NBj9EZ//YJyqAVJV/cMPr6JsmY2ZKHNXU0fpIWB7zQ1fS2SjXPffwGdhvRkxCHQg0gan6mhp/WMcCA==","signature_status":"signed_v1","signed_at":"2026-05-18T01:23:11.048349Z","signed_message":"canonical_sha256_bytes"},"source_id":"1601.01927","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:18685fa8fc62614cc3374410426af64fb35b869bdec4e309f65dab396302f6b8","sha256:0d06f5cd0bd55d9d7dd22e265534fdb9dd9cb5fd173540f8c41b987d326fe7e3"],"state_sha256":"87825b87cd8bb7ad840c6b329947291cf6181c3be498eb20c017f1b90ca33a22"}