{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2012:URHU76F232BZT37LBYITPSB2LC","short_pith_number":"pith:URHU76F2","canonical_record":{"source":{"id":"1206.1098","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.MN","submitted_at":"2012-06-06T00:35:33Z","cross_cats_sorted":["cond-mat.stat-mech","physics.bio-ph","q-bio.QM"],"title_canon_sha256":"a285f74e94705667d30c245cec90de1363a80c686205ff329f2213d55dcfb2c7","abstract_canon_sha256":"7aa8a2d6d48b0d858fccdda11bb7f3b11e5bd7ae931929fa426715be7afce280"},"schema_version":"1.0"},"canonical_sha256":"a44f4ff8bade8399efeb0e1137c83a588c39d9b2e8cb97e96a80e96df69fa7a1","source":{"kind":"arxiv","id":"1206.1098","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1206.1098","created_at":"2026-05-18T01:57:07Z"},{"alias_kind":"arxiv_version","alias_value":"1206.1098v1","created_at":"2026-05-18T01:57:07Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1206.1098","created_at":"2026-05-18T01:57:07Z"},{"alias_kind":"pith_short_12","alias_value":"URHU76F232BZ","created_at":"2026-05-18T12:27:23Z"},{"alias_kind":"pith_short_16","alias_value":"URHU76F232BZT37L","created_at":"2026-05-18T12:27:23Z"},{"alias_kind":"pith_short_8","alias_value":"URHU76F2","created_at":"2026-05-18T12:27:23Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2012:URHU76F232BZT37LBYITPSB2LC","target":"record","payload":{"canonical_record":{"source":{"id":"1206.1098","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.MN","submitted_at":"2012-06-06T00:35:33Z","cross_cats_sorted":["cond-mat.stat-mech","physics.bio-ph","q-bio.QM"],"title_canon_sha256":"a285f74e94705667d30c245cec90de1363a80c686205ff329f2213d55dcfb2c7","abstract_canon_sha256":"7aa8a2d6d48b0d858fccdda11bb7f3b11e5bd7ae931929fa426715be7afce280"},"schema_version":"1.0"},"canonical_sha256":"a44f4ff8bade8399efeb0e1137c83a588c39d9b2e8cb97e96a80e96df69fa7a1","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T01:57:07.325151Z","signature_b64":"M1iLERh3MIl8ZCWzspWN0gl3DbTDCYvPB+GkCgNdFy+fUmYdWaQkL62gTlY5ylauZYHRHY/fLeo1bVvT6/nWCA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"a44f4ff8bade8399efeb0e1137c83a588c39d9b2e8cb97e96a80e96df69fa7a1","last_reissued_at":"2026-05-18T01:57:07.324723Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T01:57:07.324723Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1206.1098","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T01:57:07Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"YLc6Yumg/tGckEIW5Kjcx23mBm6LDy5+3VXqduB0kKp3Q4RiNwUjKpbEU7Xh1xUqldVJ7LAPHiESyXO8r98hCA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-28T09:38:27.380160Z"},"content_sha256":"e2be16943a3501891005bdd1a341dc3aab14c5827a856ce47c08a280637bdf0f","schema_version":"1.0","event_id":"sha256:e2be16943a3501891005bdd1a341dc3aab14c5827a856ce47c08a280637bdf0f"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2012:URHU76F232BZT37LBYITPSB2LC","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"The interplay of intrinsic and extrinsic bounded noises in genetic networks","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["cond-mat.stat-mech","physics.bio-ph","q-bio.QM"],"primary_cat":"q-bio.MN","authors_text":"Alberto d'Onofrio, Giancarlo Mauri, Giulio Caravagna","submitted_at":"2012-06-06T00:35:33Z","abstract_excerpt":"After being considered as a nuisance to be filtered out, it became recently clear that biochemical noise plays a complex role, often fully functional, for a genetic network. The influence of intrinsic and extrinsic noises on genetic networks has intensively been investigated in last ten years, though contributions on the co-presence of both are sparse. Extrinsic noise is usually modeled as an unbounded white or colored gaussian stochastic process, even though realistic stochastic perturbations are clearly bounded. In this paper we consider Gillespie-like stochastic models of nonlinear networks"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1206.1098","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T01:57:07Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"kVS94pVxzj2oJ/U1jV21AXbjb63rPdCYWd+17WDH5l0vUepBPP0KriIE5zJkLishMZAdDgPOj8IIghvN0mgnDQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-28T09:38:27.380526Z"},"content_sha256":"edfcc58c8321c205b8bca80d092b7a16b5d13262ebe239acaa8e6e5437fcfadd","schema_version":"1.0","event_id":"sha256:edfcc58c8321c205b8bca80d092b7a16b5d13262ebe239acaa8e6e5437fcfadd"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/URHU76F232BZT37LBYITPSB2LC/bundle.json","state_url":"https://pith.science/pith/URHU76F232BZT37LBYITPSB2LC/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/URHU76F232BZT37LBYITPSB2LC/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-05-28T09:38:27Z","links":{"resolver":"https://pith.science/pith/URHU76F232BZT37LBYITPSB2LC","bundle":"https://pith.science/pith/URHU76F232BZT37LBYITPSB2LC/bundle.json","state":"https://pith.science/pith/URHU76F232BZT37LBYITPSB2LC/state.json","well_known_bundle":"https://pith.science/.well-known/pith/URHU76F232BZT37LBYITPSB2LC/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2012:URHU76F232BZT37LBYITPSB2LC","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"7aa8a2d6d48b0d858fccdda11bb7f3b11e5bd7ae931929fa426715be7afce280","cross_cats_sorted":["cond-mat.stat-mech","physics.bio-ph","q-bio.QM"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.MN","submitted_at":"2012-06-06T00:35:33Z","title_canon_sha256":"a285f74e94705667d30c245cec90de1363a80c686205ff329f2213d55dcfb2c7"},"schema_version":"1.0","source":{"id":"1206.1098","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1206.1098","created_at":"2026-05-18T01:57:07Z"},{"alias_kind":"arxiv_version","alias_value":"1206.1098v1","created_at":"2026-05-18T01:57:07Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1206.1098","created_at":"2026-05-18T01:57:07Z"},{"alias_kind":"pith_short_12","alias_value":"URHU76F232BZ","created_at":"2026-05-18T12:27:23Z"},{"alias_kind":"pith_short_16","alias_value":"URHU76F232BZT37L","created_at":"2026-05-18T12:27:23Z"},{"alias_kind":"pith_short_8","alias_value":"URHU76F2","created_at":"2026-05-18T12:27:23Z"}],"graph_snapshots":[{"event_id":"sha256:edfcc58c8321c205b8bca80d092b7a16b5d13262ebe239acaa8e6e5437fcfadd","target":"graph","created_at":"2026-05-18T01:57:07Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"After being considered as a nuisance to be filtered out, it became recently clear that biochemical noise plays a complex role, often fully functional, for a genetic network. The influence of intrinsic and extrinsic noises on genetic networks has intensively been investigated in last ten years, though contributions on the co-presence of both are sparse. Extrinsic noise is usually modeled as an unbounded white or colored gaussian stochastic process, even though realistic stochastic perturbations are clearly bounded. In this paper we consider Gillespie-like stochastic models of nonlinear networks","authors_text":"Alberto d'Onofrio, Giancarlo Mauri, Giulio Caravagna","cross_cats":["cond-mat.stat-mech","physics.bio-ph","q-bio.QM"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.MN","submitted_at":"2012-06-06T00:35:33Z","title":"The interplay of intrinsic and extrinsic bounded noises in genetic networks"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1206.1098","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:e2be16943a3501891005bdd1a341dc3aab14c5827a856ce47c08a280637bdf0f","target":"record","created_at":"2026-05-18T01:57:07Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"7aa8a2d6d48b0d858fccdda11bb7f3b11e5bd7ae931929fa426715be7afce280","cross_cats_sorted":["cond-mat.stat-mech","physics.bio-ph","q-bio.QM"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.MN","submitted_at":"2012-06-06T00:35:33Z","title_canon_sha256":"a285f74e94705667d30c245cec90de1363a80c686205ff329f2213d55dcfb2c7"},"schema_version":"1.0","source":{"id":"1206.1098","kind":"arxiv","version":1}},"canonical_sha256":"a44f4ff8bade8399efeb0e1137c83a588c39d9b2e8cb97e96a80e96df69fa7a1","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"a44f4ff8bade8399efeb0e1137c83a588c39d9b2e8cb97e96a80e96df69fa7a1","first_computed_at":"2026-05-18T01:57:07.324723Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T01:57:07.324723Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"M1iLERh3MIl8ZCWzspWN0gl3DbTDCYvPB+GkCgNdFy+fUmYdWaQkL62gTlY5ylauZYHRHY/fLeo1bVvT6/nWCA==","signature_status":"signed_v1","signed_at":"2026-05-18T01:57:07.325151Z","signed_message":"canonical_sha256_bytes"},"source_id":"1206.1098","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:e2be16943a3501891005bdd1a341dc3aab14c5827a856ce47c08a280637bdf0f","sha256:edfcc58c8321c205b8bca80d092b7a16b5d13262ebe239acaa8e6e5437fcfadd"],"state_sha256":"2ff8512ba41457b74ae83250fb7fa7b8a22ff88646db9232269e727d6a1e9908"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"szYz9DRYgUU+ZaVkYAeQ9GY+nd+qYdvCU6iShFtSTm8YaZW72nRt9A9y16xJ91jJPPK0DnIMcZ/vrlUKc6rcDw==","signed_message":"bundle_sha256_bytes","signed_at":"2026-05-28T09:38:27.382507Z","bundle_sha256":"9ba4e6ebae6ee01754d8417a55d88891ca0b51e0b9379684d774452d758b8264"}}